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LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008].. Additionally we are shipping Lcor Antibodies (49) and Lcor Kits (2) and many more products for this protein.
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These findings suggest that transactivation activities of Mlr1 and Mlr2 are differentially regulated by splicing variants of NOL4, which are expressed in a tissue-selective manner.
identification and characterization of Mlr2 a homolog of Mblk-1, a transcription factor from the honeybee brain; expressed in various tissues other than testis
LCoR recruitment by KLF6 (show KLF6 Proteins) regulates expression of the cyclin-dependent kinase (show CDK1 Proteins) inhibitor CDKN1A gene.
Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.
These results showed that the presence of miR (show MLXIP Proteins)-615-3p repressed the expression of LCoR, a derepressor of peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG Proteins)).
Data show that LCoR (ligand-dependent nuclear receptor corepressor) represents a class of corepressor that attenuates agonist-activated nuclear receptor signaling by multiple mechanisms [Ligand-dependent nuclear receptor corepressor].
HDAC6 (show HDAC6 Proteins) can function as a cofactor of LCoR but they can act to enhance expression of specific estrogen-regulated genes
role for LCoR and CtBP1 (show CTBP1 Proteins) as attenuators of progesterone-regulated transcription, but LCoR and CtBP1 (show CTBP1 Proteins) can act to enhance transcription of some genes
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003
ligand dependent nuclear receptor corepressor
, ligand-dependent corepressor
, Mblk1-related protein-2
, mblk1-related protein 2
, transcription factor MLR2