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Limb Bud and Heart Development (LBH) ELISA Kits

Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.. Additionally we are shipping LBH Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LBH LBH 81606 Q53QV2
Anti-Mouse LBH LBH 77889 Q9CX60
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More ELISA Kits for LBH Interaction Partners

Human Limb Bud and Heart Development (LBH) interaction partners

  1. LBH normally induces NPC (show NPC1 ELISA Kits) cell cycle arrest at the G1/S transition, and LBH can suppress the growth of transplanted NPC (show NPC1 ELISA Kits) tumors in vivo by downregulating LMP1 (show PDLIM7 ELISA Kits)-mediated NF-kappaB (show NFKB1 ELISA Kits) transcriptional activity.

  2. LBH is a candidate gene for synovial pathology in rheumatoid arthritis. It is regulated by growth factors and modulates cell growth in primary fibroblast-like synoviocytes.

  3. results showed that the interaction of LBH and alphaB-crystallin (show CRYAB ELISA Kits) may inhibit synergistically the transcriptional regulation of p53 (show TP53 ELISA Kits) and p21 (show CDKN1A ELISA Kits)

  4. LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1 (show WNT1 ELISA Kits)-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) hyperactivation.

  5. LBH is implicated as a candidate gene for congenital heart disease associated with partial trisomy 2p syndrome

  6. These results suggest that hLBH proteins may act as a transcriptional activator in mitogen-activated protein kinase (show MAPK1 ELISA Kits) signaling pathway to mediate cellular functions.

Mouse (Murine) Limb Bud and Heart Development (LBH) interaction partners

  1. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage.

  2. LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1 (show WNT1 ELISA Kits)-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) hyperactivation.

  3. during endochondral bone formation, Lbh may negatively regulate vascular invasion and formation of the early ossification center at least in part by interfering with Runx2 and/or VEGF expression

LBH Antigen Profile

Antigen Summary

Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.

Gene names and symbols associated with LBH

  • limb bud and heart development (LBH) antibody
  • limb bud and heart development (lbh) antibody
  • limb bud and heart development homolog (mouse) (LBH) antibody
  • limb-bud and heart (Lbh) antibody
  • 1810009F10Rik antibody
  • 6720416L16Rik antibody
  • cl2 antibody

Protein level used designations for LBH

hLBH , limb bud and heart development homolog , protein LBH , XLCL2 , cleavage 2 protein , limb bud and heart-expressed protein

GENE ID SPECIES
81606 Homo sapiens
397879 Xenopus laevis
616148 Bos taurus
421301 Gallus gallus
100172052 Pongo abelii
77889 Mus musculus
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