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Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.. Additionally we are shipping LBH Proteins (6) and many more products for this protein.
LBH normally induces NPC (show NPC1 ELISA Kits) cell cycle arrest at the G1/S transition, and LBH can suppress the growth of transplanted NPC (show NPC1 ELISA Kits) tumors in vivo by downregulating LMP1 (show PDLIM7 ELISA Kits)-mediated NF-kappaB (show NFKB1 ELISA Kits) transcriptional activity.
LBH is a candidate gene for synovial pathology in rheumatoid arthritis. It is regulated by growth factors and modulates cell growth in primary fibroblast-like synoviocytes.
results showed that the interaction of LBH and alphaB-crystallin (show CRYAB ELISA Kits) may inhibit synergistically the transcriptional regulation of p53 (show TP53 ELISA Kits) and p21 (show CDKN1A ELISA Kits)
LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1 (show WNT1 ELISA Kits)-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) hyperactivation.
LBH is implicated as a candidate gene for congenital heart disease associated with partial trisomy 2p syndrome
These results suggest that hLBH proteins may act as a transcriptional activator in mitogen-activated protein kinase (show MAPK1 ELISA Kits) signaling pathway to mediate cellular functions.
The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage.
during endochondral bone formation, Lbh may negatively regulate vascular invasion and formation of the early ossification center at least in part by interfering with Runx2 and/or VEGF expression
Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.
, limb bud and heart development homolog
, protein LBH
, cleavage 2 protein
, limb bud and heart-expressed protein