Limb-Bud and Heart Proteins (LBH)

Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.. Additionally we are shipping LBH Antibodies (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LBH 81606 Q53QV2
LBH 77889 Q9CX60
LBH    
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Top LBH Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,181.67
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,181.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 60 to 71 Days
$2,190.83
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,190.83
Details
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
$2,194.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 2 to 3 Days
$388.93
Details

LBH Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Chicken

More Proteins for Limb-Bud and Heart (LBH) Interaction Partners

Human Limb-Bud and Heart (LBH) interaction partners

  1. Low LBH level, caused by a rheumatoid arthritis risk allele, is a risk factor for aggressive fibroblast-like synoviocyte behavior.

  2. The expression levels of LBH mRNA in patients with SLE were significantly decreased compared with those in normal controls (P < 0.001). No significant differences were found between LBH mRNA expression levels and SLE disease activity scores, SNP rs7579944 and rs906868.

  3. LBH normally induces NPC (show NPC1 Proteins) cell cycle arrest at the G1/S transition, and LBH can suppress the growth of transplanted NPC (show NPC1 Proteins) tumors in vivo by downregulating LMP1 (show PDLIM7 Proteins)-mediated NF-kappaB (show NFKB1 Proteins) transcriptional activity.

  4. LBH is a candidate gene for synovial pathology in rheumatoid arthritis. It is regulated by growth factors and modulates cell growth in primary fibroblast-like synoviocytes.

  5. results showed that the interaction of LBH and alphaB-crystallin (show CRYAB Proteins) may inhibit synergistically the transcriptional regulation of p53 (show TP53 Proteins) and p21 (show CDKN1A Proteins)

  6. LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1 (show WNT1 Proteins)-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) hyperactivation.

  7. LBH is implicated as a candidate gene for congenital heart disease associated with partial trisomy 2p syndrome

  8. These results suggest that hLBH proteins may act as a transcriptional activator in mitogen-activated protein kinase (show MAPK1 Proteins) signaling pathway to mediate cellular functions.

Mouse (Murine) Limb-Bud and Heart (LBH) interaction partners

  1. These studies indicate that LBH deficiency induces S-phase arrest that, in turn, exacerbates inflammation. Because LBH gene variants are associated with type I diabetes mellitus, systemic lupus erythematosus, RA, and celiac disease, these results suggest a general mechanism that could contribute to immune-mediated diseases.

  2. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage.

  3. LBH is aberrantly overexpressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1 (show WNT1 Proteins)-transgenic mice and in aggressive basal subtype human breast cancers that display Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) hyperactivation.

  4. during endochondral bone formation, Lbh may negatively regulate vascular invasion and formation of the early ossification center at least in part by interfering with Runx2 and/or VEGF expression

LBH Protein Profile

Protein Summary

Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway.

Gene names and symbols associated with Limb-Bud and Heart Proteins (LBH)

  • limb bud and heart development (LBH)
  • limb bud and heart development homolog (mouse) (LBH)
  • limb-bud and heart (Lbh)
  • limb bud and heart development (lbh)
  • 1810009F10Rik protein
  • 6720416L16Rik protein
  • cl2 protein

Protein level used designations for Limb-Bud and Heart Proteins (LBH)

hLBH , limb bud and heart development homolog , protein LBH , limb bud and heart-expressed protein , XLCL2 , cleavage 2 protein

GENE ID SPECIES
81606 Homo sapiens
421301 Gallus gallus
616148 Bos taurus
100172052 Pongo abelii
77889 Mus musculus
397879 Xenopus laevis
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