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The protein encoded by LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Additionally we are shipping LIPG Antibodies (201) and LIPG Kits (64) and many more products for this protein.
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Human LIPG Protein expressed in HEK-293 Cells - ABIN2181479
Hutter, Austin, Farin, Viernes, Edwards, Leonetti, McNeely, Fujimoto: Association of endothelial lipase gene (LIPG) haplotypes with high-density lipoprotein cholesterol subfractions and apolipoprotein AI plasma levels in Japanese Americans. in Atherosclerosis 2006
Show all 3 references for ABIN2181479
FoxA1 (show FOXA1 Proteins), FoxA2 (show FOXA2 Proteins), and LIPG control the uptake of extracellular lipids for breast cancer growth.
results suggested that the SNP -384A/C in the LIPG gene may be associated with risk for coronary artery disease(CAD)and the LIPG gene may play a role in CAD in the Han Chinese
Studied if a specific variant of the endothelial lipase gene was more specifically linked to the severity of diabetic retinopathy.
EL-384A/C polymorphism was significantly associated with the ACS and lipids profile in an elderly Uygur population in Xinjiang.
Results showed that the protein levels of endothelial lipase (EL), NF-kappaB (show NFKB1 Proteins) p65 (show GORASP1 Proteins), MAPK p38 (show MAPK1 Proteins) protein (show RNF19A Proteins) levels, in addition to the proliferation of umbilical vein endothelial cells (HUVECs), were increased by angiotensin II (AngII).
Genetic studies of patients with early onset of coronary artery disease (CAD) in the Chinese Han population show that the EL 584C/T variant is not always involved in the pathogenesis of early-onset CAD.
The results of the present meta-analysis suggest that the carriers of EL 584 T allele have a higher HDL (show HSD11B1 Proteins)-C level in Caucasian populations. Whereas, it might not be a protective factor for CHD (show CHDH Proteins).
Results indicate the spatial consensus catalytic triad "Ser (show SIGLEC1 Proteins)-Asp (show ASIP Proteins)-His", a characteristic motif in lipoprotein lipase (show LPL Proteins), hepatic lipase (show LIPC Proteins), and endothelial lipase.
EL activity was higher in metabolic syndrome and in obesity. It was negatively associated with high-density lipoprotein-cholesterol and apolipoprotein A-I (show APOA1 Proteins) in control and metabolic syndrome, respectively.
T allele of LIPG -584C/T polymorphism might play a potential role in the susceptibility to atherogenesis in the Turkish population.
Brain capillary endothelial cells synthesize and secrete endothelial lipase (EL); EL can generate fatty acids at blood-brain barrier for transport to deeper regions of the brain as building blocks for membrane phospholipids.
inhibitory activity of AOE on pancreatic lipase (show PNLIP Proteins) enzyme was evaluated at concentrations from 60 to 1000 mug/mL. The AOE inhibited the pancreatic lipase (show PNLIP Proteins) with an IC50 = 588.5 mug/mL
Hepatic lipase (show LIPC Proteins) and endothelial lipase influence molecular species of several classes of plasma lipids.
Furin (show FURIN Proteins) has a role as the primary in vivo convertase of ANGPTL3 (show ANGPTL3 Proteins) and endothelial lipase in hepatocytes
The role of EL in HDL (show HSD11B1 Proteins)-associated S1P (show S1PR1 Proteins) effects provides new insights into EL action, the responses seen through EL and HDL (show HSD11B1 Proteins) interaction, and S1P (show S1PR1 Proteins) signaling.
Endothelial lipase may act as an alternative candidate to provide fatty acids to the heart and regulate cardiac function.
Hepatic lipase (show LIPC Proteins)- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT (show FOXE3 Proteins) and HDL (show HSD11B1 Proteins) antioxidant properties.
Endothelial lipase supplies cells with free fatty acids and HDL (show HSD11B1 Proteins)-derived lysophosphatidylcholine and lysophosphatidylethanolamine species resulting in increased cellular triglycerides and phosphatidylcholine (show SGMS2 Proteins) (PC) content and decreased PC synthesis.
EL expression modulates vascular remodeling as well as plasma HDL (show HSD11B1 Proteins)-C levels
Starvation regulates endothelial lipase expression via SREBP-2 (show SREBF2 Proteins).
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.
, lipase, endothelial
, endothelial lipase-like
, Endothelial lipase
, endothelial cell-derived lipase
, lipoprotein lipase H
, lipose, endothelial
, endothelial-derived lipase
, lipase G