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Lipin 2 Proteins (LPIN2)

Mouse studies suggest that LPIN2 functions during normal adipose tissue development and may play a role in human triglyceride metabolism. Additionally we are shipping Lipin 2 Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LPIN2 9663 Q92539
LPIN2 64898 Q99PI5
Rat LPIN2 LPIN2 316737  
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Top Lipin 2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LPIN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Lipin 2 (LPIN2) Interaction Partners

Human Lipin 2 (LPIN2) interaction partners

  1. Structural variants unique to the malignant cell line inactivated: LPIN2, a phosphatidic acid phosphatase and a co-factor of PGC1a that is important for lipid metabolism and for suppressing autoinflammation.

  2. We describe two brothers with Majeed syndrome, homozygous novel 2-base pair deletion in LPIN2 (c.1312_1313delCT; p.Leu438fs+16X)

  3. LPIN1 (show LPIN1 Proteins)-related myolysis constitutes a major cause of early-onset rhabdomyolysis and occasionally in adults. Heterozygous LPIN1 (show LPIN1 Proteins) mutations may cause mild muscular symptoms. No major defects of LPIN2 or LPIN3 (show LPIN3 Proteins) genes were associated with muscle manifestations.

  4. role of lipin-2 in the proinflammatory action of saturated fatty acids in murine and human macrophages

  5. Data revealed that lipin 1 (show LPIN1 Proteins) formed stable homo-oligomers with itself and hetero-oligomers with lipin 2/3.

  6. LPIN2 gene was excluded as a candidate for myopia 2 (MYP2), but the SNPs detected in this study will aid in future mapping and association studies involving this gene.

  7. We conclude that homozygous mutations in LPIN2 result in Majeed syndrome. Understanding the aberrant immune response in this condition will shed light on the aetiology of other inflammatory disorders of multifactorial aetiology

  8. A single nucleotide polymorphism of the LPIN2 gene is associated with type 2 diabetes and fat distribution.

  9. distinct and non-redundant functions of lipin 1 (show LPIN1 Proteins) and 2 regulate lipid production during the cell cycle and adipocyte differentiation

  10. lipin 2 plays an important role as a hepatic PAP-1 enzyme.

Pig (Porcine) Lipin 2 (LPIN2) interaction partners

  1. Association analysis showed that different genotypes of LPIN2 were associated with back-fat thickness between the 6th and 7th ribs (P < 0.01).

Mouse (Murine) Lipin 2 (LPIN2) interaction partners

  1. Lipin 2 binds phosphatidic acid by the electrostatic hydrogen bond but the phosphorylation of lipin 2 is not induced by insulin (show INS Proteins) signaling.

  2. in addition to their roles during early adipogenesis, lipin1 (show LPIN1 Proteins) and lipin2 also have a role in lipid droplet biogenesis.

  3. Mouse lipin-1 (show LPIN1 Proteins) and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum.

  4. role of lipin-2 in the proinflammatory action of saturated fatty acids in murine and human macrophages

  5. Data show that in the high-Chol diet apoE (show APOE Proteins)-KO mice, the mRNA and protein expression of lipin-1 (show LPIN1 Proteins) and lipin-2 was markedly decreased.

  6. The results demonstrate that ER stress-induced LIPIN2 would contribute to the perturbation of hepatic insulin (show INS Proteins) signaling via a DAG-protein kinase C epsilon (show PRKCE Proteins)-dependent manner in DIO mice.

  7. Lipin-2 exhibits phosphatidate phosphatase type-1 (PAP1) activity, which has a key role in glycerolipid synthesis.

  8. distinct and non-redundant functions of lipin 1 (show LPIN1 Proteins) and 2 regulate lipid production during the cell cycle and adipocyte differentiation

  9. lipin 2 plays an important role as a hepatic PAP-1 enzyme.

  10. A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 (show LPIN1 Proteins) and lipin-2.

Lipin 2 (LPIN2) Protein Profile

Protein Summary

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.

Gene names and symbols associated with Lipin 2 Proteins (LPIN2)

  • lipin 2 (lpin2)
  • lipin 2 (LPIN2)
  • lipin 2 (lipin2)
  • lipin 2 (LOC100230735)
  • lipin 2 (LOC100348321)
  • lipin 2 (Lpin2)
  • 2610511G02Rik protein
  • AI481352 protein
  • AW742896 protein
  • LOC100230735 protein
  • LPIN2 protein
  • MGC68631 protein
  • MGC146375 protein
  • si:dkey-216e9.8 protein

Protein level used designations for Lipin 2 Proteins (LPIN2)

lipin 2 , phosphatidate phosphatase LPIN2 , phosphatidate phosphatase LPIN2-like , lipin-2

GENE ID SPECIES
398816 Xenopus laevis
421059 Gallus gallus
455317 Pan troglodytes
514448 Bos taurus
558422 Danio rerio
607640 Canis lupus familiaris
695641 Macaca mulatta
779972 Xenopus (Silurana) tropicalis
100230735 Taeniopygia guttata
100348321 Oryctolagus cuniculus
100414205 Callithrix jacchus
100451550 Pongo abelii
100466187 Ailuropoda melanoleuca
100012110 Monodelphis domestica
100051300 Equus caballus
100566027 Anolis carolinensis
9663 Homo sapiens
100187579 Sus scrofa
64898 Mus musculus
316737 Rattus norvegicus
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