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Lipin 3 Proteins (LPIN3)

Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Additionally we are shipping LPIN3 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LPIN3 64900 Q9BQK8
LPIN3 64899 Q99PI4
Rat LPIN3 LPIN3 362261  
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Top LPIN3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

LPIN3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Lipin 3 (LPIN3) Interaction Partners

Pig (Porcine) Lipin 3 (LPIN3) interaction partners

  1. Association analysis showed that different genotypes of LPIN2 (show LPIN2 Proteins) were associated with back-fat thickness between the 6th and 7th ribs (P < 0.01).

Human Lipin 3 (LPIN3) interaction partners

  1. a newly identified novel cell-penetrating sequence (LPIN; RRKRRRRRK) from the nuclear localization sequence (NLS (show ALDH1A2 Proteins)) of human nuclear phosphatase, LPIN3.

  2. LPIN1 (show LPIN1 Proteins)-related myolysis constitutes a major cause of early-onset rhabdomyolysis and occasionally in adults. Heterozygous LPIN1 (show LPIN1 Proteins) mutations may cause mild muscular symptoms. No major defects of LPIN2 (show LPIN2 Proteins) or LPIN3 genes were associated with muscle manifestations.

  3. Data revealed that lipin 1 (show LPIN1 Proteins) formed stable homo-oligomers with itself and hetero-oligomers with lipin 2 (show LPIN2 Proteins)/3.

Mouse (Murine) Lipin 3 (LPIN3) interaction partners

  1. Lipin-3 exhibits phosphatidate phosphatase type-1 (PAP1) activity, which has a key role in glycerolipid synthesis.

LPIN3 Protein Profile

Protein Summary

Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.\; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively.

Gene names and symbols associated with Lipin 3 Proteins (LPIN3)

  • lipin 3 (lpin3)
  • lipin 3 (LPIN3)
  • lipin 3 (LOAG_08747)
  • lipin 3 (LOC100348186)
  • lipin 3 (Lpin3)
  • 9130206L11Rik protein
  • AA438110 protein
  • AV236139 protein
  • dJ450M14.2 protein
  • dJ450M14.3 protein
  • dJ620E11.2 protein
  • DKFZp469D075 protein
  • LIPN3L protein
  • LPIN3 protein
  • MGC82840 protein
  • mKIAA4023 protein
  • SMP2 protein

Protein level used designations for Lipin 3 Proteins (LPIN3)

lipin 3 , phosphatidate phosphatase LPIN3 , phosphatidate phosphatase LPIN3-like , lipin-3

GENE ID SPECIES
444361 Xenopus laevis
485876 Canis lupus familiaris
521637 Bos taurus
9946175 Loa loa
100170771 Sus scrofa
100171775 Pongo abelii
100348186 Oryctolagus cuniculus
100480077 Ailuropoda melanoleuca
100559740 Anolis carolinensis
100585975 Nomascus leucogenys
64900 Homo sapiens
64899 Mus musculus
362261 Rattus norvegicus
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