anti-Lipoprotein Lipase (LPL) Antibodies

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. Additionally we are shipping Lipoprotein Lipase Kits (61) and Lipoprotein Lipase Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LPL 4023 P06858
LPL 16956 P11152
LPL 24539 Q06000
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Top anti-Lipoprotein Lipase Antibodies at antibodies-online.com

Showing 10 out of 140 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cat Mouse Un-conjugated ELISA, FACS, IF, InhA, WB 0.1 mL Log in to see 7 to 8 Days
$455.84
Details
Cow Mouse Un-conjugated EIA, Func, IHC (fro), WB   50 μg Log in to see 6 to 8 Days
$346.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-LPL AntibodyTitration: 1.0 µg/mL  Positive Control: RPMI-8226 Whole Cell  LPL is supported by BioGPS gene expression data to be expressed in RPMI 8226 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using LPL mouse mAb against Hela cell lysate (1) . 100 μL Log in to see 2 to 3 Days
$393.80
Details
Cow Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Cow Rabbit Un-conjugated WB Western blot with LPL Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB LPL Antibody (Center) (ABIN658091) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the LPL antibody detected the LPL protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-LPL mouse monoclonal antibody (ABIN2455254) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LPL (RC203766). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LPL. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LPL. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC203766 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-LPL antibody (ABIN2455197), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-LPL. 100 μL Log in to see 2 to 3 Days
$423.50
Details

LPL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lipoprotein Lipase Antibodies

  1. Cat (Feline) Monoclonal Lipoprotein Lipase Primary Antibody for ELISA, FACS - ABIN1042621 : Peterson, Ayyobi, Ma, Henderson, Reina, Deeb, Santamarina-Fojo, Hayden, Brunzell: Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene. in Journal of lipid research 2002 (PubMed)
    Show all 4 references for 1042621

  2. Human Monoclonal Lipoprotein Lipase Primary Antibody for ELISA, WB - ABIN969262 : Berk, Johnson, Lee, Zhang, Boozer, Pi-Sunyer, Fried, Albu: Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal women. in Obesity (Silver Spring, Md.) 2008 (PubMed)
    Show all 2 references for 969262

  3. Cow (Bovine) Polyclonal Lipoprotein Lipase Primary Antibody for WB - ABIN3043618 : Yu, Dai, Chen, Zang, Deng, Liu, Ying: Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats. in Carbohydrate polymers 2013 (PubMed)
    Show all 2 references for 3043618

  4. Cow (Bovine) Monoclonal Lipoprotein Lipase Primary Antibody for EIA, Func - ABIN125994 : Voyta, Via, Kinnunen, Sparrow, Gotto, Smith: Monoclonal antibodies against bovine milk lipoprotein lipase. Characterization of an antibody specific for the apolipoprotein C-II binding site. in The Journal of biological chemistry 1985 (PubMed)

More Antibodies against Lipoprotein Lipase Interaction Partners

Human Lipoprotein Lipase (LPL) interaction partners

  1. novel mutations cause type 1 hyperlipoproteinemia by inducing a loss or reduction in LPL (show LCP1 Antibodies) secretion accompanied by a loss of LPL (show LCP1 Antibodies) enzymatic activity

  2. LPL (show LCP1 Antibodies) HindIII polymorphism was significantly associated with the risk of coronary artery disease (CAD (show CAD Antibodies)); for Ser447X polymorphism, it was found that only XX genotype was significantly associated with CAD (show CAD Antibodies) risk; PvuII polymorphism had no significant association with CAD (show CAD Antibodies) risk; LPL (show LCP1 Antibodies) HindIII polymorphism might serve as a potential biomarker for CAD (show CAD Antibodies) risk

  3. Rare variants in LPL (show LCP1 Antibodies) and a common variant in APOA5 (show APOA5 Antibodies) were more commonly found in Thai subjects with severe hypertriglyceridemia

  4. apoC-I (show APOC1 Antibodies) inhibited in situ LPL (show LCP1 Antibodies) activity in adipocytes in both a concentration- and time-dependent manner. There was no change in postprandial WAT apoC-I (show APOC1 Antibodies) secretion. WAT apoC-I (show APOC1 Antibodies) secretion may inhibit WAT LPL (show LCP1 Antibodies) activity and promote delayed chylomicron clearance in overweight and obese subjects

  5. isothermal titration calorimetry (ITC) can be used for quantitative measurements of LPL (show LCP1 Antibodies) activity and interactions under in vivo-like conditions, for comparisons of the properties of plasma samples from patients and control subjects as substrates for LPL (show LCP1 Antibodies), as well as for testing of drug candidates developed with the aim to affect the LPL (show LCP1 Antibodies) system.

  6. mAbs RE3 and RG3 bound with reduced affinity to a mutant GPIHBP1 (show GPIHBP1 Antibodies) containing an Ly6 domain mutation (W109S) that abolishes LPL (show LCP1 Antibodies) binding. Immunohistochemistry studies with the GPIHBP1 (show GPIHBP1 Antibodies) mAbs revealed that human GPIHBP1 (show GPIHBP1 Antibodies) is expressed only in capillary endothelial cells. Finally, we created an ELISA that detects GPIHBP1 (show GPIHBP1 Antibodies) in human plasma.

  7. Iotansulin decreased LPL (show LCP1 Antibodies) mRNA levels in HepG2 cells and this was associated with phosphorylation of AKT (show AKT1 Antibodies) and nuclear export of FOXA2 (show FOXA2 Antibodies).

  8. The binding of both antibody 88B8 and GPIHBP1 (show GPIHBP1 Antibodies) to LPL (show LCP1 Antibodies) depends on large segments of LPL's carboxyl-terminal domain.

  9. Loss of Lipoprotein Lipase is associated with Pancreatitis.

  10. In this study, most of the LPL (show LCP1 Antibodies) gene variants were not significantly different in adolescents with normal and elevated triglceryide levels

Cow (Bovine) Lipoprotein Lipase (LPL) interaction partners

  1. isothermal titration calorimetry (ITC) can be used for quantitative measurements of LPL activity and interactions under in vivo-like conditions, for comparisons of the properties of plasma samples from patients and control subjects as substrates for LPL, as well as for testing of drug candidates developed with the aim to affect the LPL system.

  2. miR (show MYLIP Antibodies)-29b targets LPL and TDG (show TDG Antibodies) genes and regulates apoptosis and triglyceride production in mammary epithelial cells.

  3. apoC-I (show APOC1 Antibodies) and apoC-III (show APOC3 Antibodies) inhibit lipolysis by displacing LPL from lipid emulsion particles. We also propose a role for these apolipoproteins in the irreversible inactivation of LPL by factors such as angptl4 (show ANGPTL4 Antibodies).

  4. ANGPTL4 (show ANGPTL4 Antibodies) is more accurately described as a reversible, noncompetitive inhibitor of LPL.

  5. Our findings confirmed that three novel SNPs we identified in the LPL gene can affect fatty acid composition and carcass traits. Therefore, selection for AA and GA genotypes should be recommended to genetically improve beef quality and flavor.

  6. Single nucleotide polymorphisms of the LPL gene might be useful genetic markers for growth traits in the bovine reproduction and breeding.

  7. Results describe the functional role of the secondary structure in the lipoprotein lipase-binding portion of apolipoprotein CII (show APOC2 Antibodies).

  8. regions that are responsive to activation by apoC-II (show APOC2 Antibodies)

  9. domain (192-238) is absolutely necessary for apolipoprotein AV (show APOA5 Antibodies) in lipid binding and lipoprotein lipase activation

Mouse (Murine) Lipoprotein Lipase (LPL) interaction partners

  1. Using in vitro ketosis model by glucose starvation, studied inhibition of ketosis by momilactone B. Found momilactone B could regulate the angiopoietin-like-3 (ANGPTL3 (show ANGPTL3 Antibodies))-lipoprotein lipase (LPL)pathway, and suppressed the expression of HMGCS2 (show HMGCS2 Antibodies) through the increased expression of STAT5b (show STAT5B Antibodies).

  2. physiological changes in adipose tissue ANGPTL4 (show ANGPTL4 Antibodies) expression during fasting and cold resulted in inverse changes in the amount of mature-glycosylated LPL in wild-type mice, but not Angptl4 (show ANGPTL4 Antibodies)(-/-) mice. We conclude that ANGPTL4 (show ANGPTL4 Antibodies) promotes loss of intracellular LPL by stimulating LPL degradation after LPL processing in the endoplasmic reticulum (ER).

  3. LPL moved quickly from heparan sulfate proteoglycans (HSPGs) on adipocytes to GPIHBP1 (show GPIHBP1 Antibodies)-coated beads, thereby depleting LPL stores on the surface of adipocytes. We conclude that HSPG (show SDC2 Antibodies)-bound LPL in the interstitial spaces of tissues is mobile, allowing the LPL to move to GPIHBP1 (show GPIHBP1 Antibodies) on endothelial cells

  4. our study reveals that hepatic LPL is involved in the regulation of plasma LPL activity and lipid homeostasis.

  5. The induction of LPL activity by fasting in core transgenic mice activated PPARalpha (show PPARA Antibodies) downstream target genes that are involved in fatty acid beta-oxidation.

  6. This study shows that TNF-alpha (show TNF Antibodies), by a Foxo1 (show FOXO1 Antibodies) dependent pathway, increases the transcription of ANGPTL4 (show ANGPTL4 Antibodies) which is secreted by the cells and causes inactivation of LPL.

  7. Our findings suggest that neuronal LPL is involved in the regulation of body weight and composition in response to either the change in quantity (HF feeding) or quality (n-3 PUFA-enriched) of dietary fat

  8. An LPL structural model suggests that the LPL S447X truncation exposes residues implicated in LPL binding to lipoprotein binding uptake receptors, such as GPIHBP1 (show GPIHBP1 Antibodies).

  9. feeding induces lipasin, activating the lipasin-Angptl3 (show ANGPTL3 Antibodies) pathway, which inhibits LPL in cardiac and skeletal muscles to direct circulating TAG to WAT for storage

  10. MiR (show MLXIP Antibodies)-590 agomir down-regulates LPL mRNA and protein expression in a mouse model of atherosclerosis.

Lipoprotein Lipase (LPL) Antigen Profile

Protein Summary

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

Gene names and symbols associated with LPL

  • lipoprotein lipase (lpl) antibody
  • lipoprotein lipase (LPL) antibody
  • lipoprotein lipase (LOC100223817) antibody
  • lipoprotein lipase (Lpl) antibody
  • Lipoprotein lipase-like (LOC100340171) antibody
  • fb62e04 antibody
  • fc49b03 antibody
  • HDLCQ11 antibody
  • LIPD antibody
  • LOC100223817 antibody
  • lpl antibody
  • wu:fb62e04 antibody
  • wu:fc49b03 antibody

Protein level used designations for LPL

lipoprotein lipase , O 1-4-5 , adipose lipoprotein lipase , triacylglycerol lipase

GENE ID SPECIES
30354 Danio rerio
464031 Pan troglodytes
100126663 Papio anubis
100127862 Xenopus (Silurana) tropicalis
100136622 Oncorhynchus mykiss
100223817 Taeniopygia guttata
712887 Macaca mulatta
100534504 Oreochromis niloticus
4023 Homo sapiens
280843 Bos taurus
16956 Mus musculus
24539 Rattus norvegicus
396219 Gallus gallus
403626 Canis lupus familiaris
100055358 Equus caballus
397537 Sus scrofa
727696 Felis catus
100135570 Cavia porcellus
443408 Ovis aries
100860750 Capra hircus
100340171 Oryctolagus cuniculus
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