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anti-Low Density Lipoprotein Receptor (LDLR) Antibodies

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Additionally we are shipping LDLR Kits (39) and LDLR Proteins (32) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDLR 3949 P01130
LDLR 16835 P35951
LDLR 300438 P35952
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Top anti-LDLR Antibodies at antibodies-online.com

Showing 10 out of 246 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of LDLR Antibody (Center) (ABIN652907) in mouse lung tissue lysates (35 µg/lane). LDLR (arrow) was detected using the purified polyclonal antibody. LDLR Antibody (Center) (ABIN652907) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Chicken Un-conjugated EIA, IHC (p), WB Immunohistochemistry of LDL-R in human liver tissue with this product at 2.5 μg/ml. Western blot analysis of LDL-R in human liver tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of LDLR expression in Jurkat cell (Lane 1) and 3T3 (Lane 2) cell lysates. 100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, SimWes, WB Simple Western: LDL R Antibody [NBP1-06709] - Simple Western lane view shows a specific band for LDL R in 0.05 mg/ml of HepG2 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Log in to see 5 to 7 Days
$473.81
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled Anti-LDL receptor Polyclonal Antibody, Unconjugated (ABIN672111) at 1:200, followed by conjugation to the secondary antibody and DAB staining Human colon lysates probed with Anti LDL Receptor Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse PE FACS Detection of LDL R in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human LDL R PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$387.19
Details
Human Mouse Allophycocyanin FACS Detection of LDL R in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human LDL R APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$446.25
Details
Mouse Rat Un-conjugated FACS, WB Detection of LDL R in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse LDL R Monoclonal Antibody. Detection of mouse LDL R by Western Blot. Western blot shows lysates of mouse liver tissue. PVDF membrane was probed with 2 ug/mL of Rat Anti-Mouse LDL R Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 6 to 7 Days
$334.69
Details
Human Mouse Un-conjugated ELISA (Capture), FACS, IP, WB Detection of LDL R in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human LDL R Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$367.50
Details
Cow Mouse Un-conjugated ELISA, EM, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, in vitro, RIA, WB Immunohistochemistry: LDL R Antibody (C7) [NBP1-78159] - IHC analysis of a formalin fixed paraffin embedded tissue section of human liver using LDL Receptor antibody (clone C7) with HRP-DAB based detection and hematoxylin counterstaining. Immunocytochemistry/Immunofluorescence: LDL R Antibody (C7) [NBP1-78159] - Antibody was tested in HepG2 cells with FITC (green). Nuclei were counterstained with Dapi (blue). 0.1 mL Log in to see 5 to 7 Days
$408.19
Details

LDLR Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-LDLR Antibodies

  1. Cow (Bovine) Monoclonal LDLR Primary Antibody for ELISA, EM - ABIN4330573 : Jørgensen, Jensen, Holst, Hansen, Corydon, Bross, Bolund, Gregersen: Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum. in The Journal of biological chemistry 2000 (PubMed)
    Show all 16 references for ABIN4330573

  2. Cow (Bovine) Polyclonal LDLR Primary Antibody for WB - ABIN223504 : Dong, Wu, Li, Kraemer, Adeli, Seidah, Park, Liu: Strong induction of PCSK9 gene expression through HNF1{alpha} and SREBP2: Mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. in Journal of lipid research 2010 (PubMed)
    Show all 7 references for ABIN223504

  3. Human Polyclonal LDLR Primary Antibody for IF (p), IHC (p) - ABIN672111 : Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. in Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 (PubMed)
    Show all 4 references for ABIN672111

  4. Human Monoclonal LDLR Primary Antibody for ELISA (Capture), FACS - ABIN4899696 : Boucrot, Ferreira, Almeida-Souza, Debard, Vallis, Howard, Bertot, Sauvonnet, McMahon: Endophilin marks and controls a clathrin-independent endocytic pathway. in Nature 2015 (PubMed)
    Show all 3 references for ABIN4899696

  5. Human Polyclonal LDLR Primary Antibody for ICC, IF - ABIN438622 : Wang, Gao, Liao, Qi, Du, Wang, Li, Liu, Yang: Adipose tissue deficiency results in severe hyperlipidemia and atherosclerosis in the low-density lipoprotein receptor knockout mice. in Biochimica et biophysica acta 2016 (PubMed)
    Show all 3 references for ABIN438622

  6. Human Monoclonal LDLR Primary Antibody for FACS - ABIN4896539 : Le, Blanchet, Seidah, Labonté: Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9. in The Journal of biological chemistry 2015 (PubMed)
    Show all 3 references for ABIN4896539

  7. Human Monoclonal LDLR Primary Antibody for FACS - ABIN4896543 : Ramanathan, Gusarova, Stahl, Gurnett-Bander, Kyratsous: Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes. in PLoS ONE 2016 (PubMed)
    Show all 3 references for ABIN4896543

  8. Human Polyclonal LDLR Primary Antibody for EIA, IHC (p) - ABIN500146 : Li, Cam, Bu: Low-density lipoprotein receptor family: endocytosis and signal transduction. in Molecular neurobiology 2001 (PubMed)

  9. Mouse (Murine) Monoclonal LDLR Primary Antibody for FACS, WB - ABIN4899699 : Rousselet, Marcinkiewicz, Kriz, Zhou, Hatten, Prat, Seidah: PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke. in Journal of lipid research 2011 (PubMed)

  10. Human Polyclonal LDLR Primary Antibody for FACS, WB - ABIN652907 : Brown, Goldstein: Receptor-mediated endocytosis: insights from the lipoprotein receptor system. in Proceedings of the National Academy of Sciences of the United States of America 1979 (PubMed)

More Antibodies against LDLR Interaction Partners

Human Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Multiple novel LDLR and ApoB (show APOB Antibodies) mutations have been identified in a-United Kingdom-based cohort with familial hypercholesterolemia.

  2. Mutations in LDLR is associated with coronary artery disease.

  3. LDLR A(+)A(+) genotype, ApoB (show APOB Antibodies) X(+) allele and ApoE (show APOE Antibodies) E4 allele increased the risk of premature coronary artery disease by 1.8, 2.1 and 12.1 respectively.

  4. The TT genotype of rs688 in the LDLR gene was not found to be associated with elevated levels of total cholesterol or LDL-C

  5. Report increased intestinal cholesterol absorption and elevated serum cholesterol in families with primary hypercholesterolemia without mutations in LDLR.

  6. genetic confirmation of ADH (show AVP Antibodies) may be important to identify patient's risk of CHD (show CHDH Antibodies), especially for female LDLR mutation carriers

  7. Specifically, loss of IDOL (show MYLIP Antibodies) increases LDLR distribution in the hepatic cell, and subsequently reduces serum LDL-C levels in dyslipidemic patients.

  8. de novo mutation of the LDL receptor gene as the cause of familial hypercholesterolemia

  9. A recurrent frameshift mutation in LDLR gene causing familial hypercholesterolemia was identified in 9 probands and their relatives.

  10. LDL receptor gene polymorphisms play a role in the treatment response of hepatitis C and the modulation of disease progression in Egyptians infected with chronic HCV.

Cow (Bovine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE (show APOE Antibodies), MTP (show MTTP Antibodies), and LDLR, thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

Mouse (Murine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor and expressing only ApoB100 (show APOB Antibodies) molecule (ApoB (show APOB Antibodies)-LDLr) where the development of atherosclerosis is known to closely mimic human atherosclerosis

  2. Atherosclerosis is accelerated in LDL receptor-deficient mice fed a high-fat diet.

  3. Myeloid cell IFNGR2 (show IFNGR2 Antibodies) deficiency does not affect atherosclerosis development in LDLR knockout mice.

  4. HDL (show HSD11B1 Antibodies) is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile

  5. Neurometabolic roles of ApoE (show APOE Antibodies) and Ldl-R in mouse brain.

  6. Absence of Elovl6 (show ELOVL6 Antibodies) attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.

  7. Suggest Idol (show MYLIP Antibodies) as a gatekeeper of LDLR-dependent ApoE (show APOE Antibodies) and Abeta (show APP Antibodies) clearance in the brain and a potential enzyme target for therapeutic intervention in Alzheimer disease.

  8. binding of PCSK9 (show PCSK9 Antibodies) to GRP94 (show HSP90B1 Antibodies) protects LDLR from degradation likely by preventing early binding of PCSK9 (show PCSK9 Antibodies) to LDLR

  9. Short-term modulation of miR (show MLXIP Antibodies)-27b expression in wild-type mice regulates hepatic LDLR and ABCA1 (show ABCA1 Antibodies) expression but does not influence plasma and hepatic lipid levels.

  10. miR (show MLXIP Antibodies)-185 controls cholesterol homeostasis as a key posttranscriptional LDLR modulator in hepatic cells, providing novel insight into the regulatory mechanism for LDLR expression and the anti-atherosclerosis effect of miR (show MLXIP Antibodies)-185-inhibitor.

Pig (Porcine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. The LDLR gene should be a candidate causative gene for LDL-cholesterol and total cholesterol in pigs, but heterogeneity exists in different populations.

  2. KLF13 (show KLF13 Antibodies) and SREBP-Sp1 (show SP1 Antibodies) activation interact to regulate low density lipoprotein receptor promoter function

  3. found association between genotypes for LDLR and APOB (show APOB Antibodies) polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

LDLR Antigen Profile

Protein Summary

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with LDLR

  • low density lipoprotein receptor (ldlr) antibody
  • low density lipoprotein receptor (LDLR) antibody
  • low density lipoprotein receptor (Ldlr) antibody
  • low density protein receptor (LOC443535) antibody
  • FH antibody
  • FHC antibody
  • Hlb301 antibody
  • LDLA antibody
  • LDLCQ2 antibody
  • LDLRA antibody

Protein level used designations for LDLR

low-density lipoprotein receptor , LDL receptor , low-density lipoprotein receptor class A domain-containing protein 3 , low density lipoprotein receptor (familial hypercholesterolemia)

GENE ID SPECIES
387529 Danio rerio
3949 Homo sapiens
281276 Bos taurus
100009086 Oryctolagus cuniculus
16835 Mus musculus
300438 Rattus norvegicus
100724238 Cavia porcellus
396801 Sus scrofa
100683160 Canis lupus familiaris
395103 Gallus gallus
100689399 Cricetulus griseus
443535 Ovis aries
Selected quality suppliers for anti-LDLR (LDLR) Antibodies
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