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anti-Low Density Lipoprotein Receptor (LDLR) Antibodies

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Additionally we are shipping LDLR Kits (45) and LDLR Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDLR 3949 P01130
LDLR 16835 P35951
LDLR 300438 P35952
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Top anti-LDLR Antibodies at antibodies-online.com

Showing 10 out of 228 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of LDLR Antibody (Center) (ABIN652907) in mouse lung tissue lysates (35 µg/lane). LDLR (arrow) was detected using the purified polyclonal antibody. LDLR Antibody (Center) (ABIN652907) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of LDLR expression in Jurkat cell (Lane 1) and 3T3 (Lane 2) cell lysates. 100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Chicken Un-conjugated EIA, IHC (p), WB Immunohistochemistry of LDL-R in human liver tissue with this product at 2.5 μg/ml. Western blot analysis of LDL-R in human liver tissue lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled Anti-LDL receptor Polyclonal Antibody, Unconjugated (ABIN672111) at 1:200, followed by conjugation to the secondary antibody and DAB staining Human colon lysates probed with Anti LDL Receptor Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Cow Mouse Un-conjugated FACS, IF, WB   50 μg Log in to see 6 to 8 Days
$357.50
Details
Cow Mouse Biotin FACS, IHC (fro), WB   1 mL Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit Un-conjugated FACS, IHC (fro), WB   0.25 mL Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LDLR is approximately 0.3ng/ml as a capture antibody. Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR monoclonal antibody (M01), clone 5E7.Lane 1: LDLR transfected lysate(94.6 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Biotin FACS   0.25 mL Log in to see 6 to 8 Days
$489.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, SimWes, WB 0.025 mL Log in to see 5 to 7 Days
$203.44
Details

LDLR Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-LDLR Antibodies

  1. Cow (Bovine) Polyclonal LDLR Primary Antibody for WB - ABIN223504 : Dong, Wu, Li, Kraemer, Adeli, Seidah, Park, Liu: Strong induction of PCSK9 gene expression through HNF1{alpha} and SREBP2: Mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. in Journal of lipid research 2010 (PubMed)
    Show all 7 references for ABIN223504

  2. Cow (Bovine) Monoclonal LDLR Primary Antibody for FACS, IHC (fro) - ABIN112188 : Beisiegel, Schneider, Brown, Goldstein: Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia. in The Journal of biological chemistry 1982 (PubMed)
    Show all 4 references for ABIN112188

  3. Cow (Bovine) Monoclonal LDLR Primary Antibody for FACS, IF - ABIN112187 : Beisiegel, Schneider, Goldstein, Anderson, Brown: Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia. in The Journal of biological chemistry 1982 (PubMed)
    Show all 4 references for ABIN112187

  4. Human Polyclonal LDLR Primary Antibody for IF (p), IHC (p) - ABIN672111 : Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. in Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 (PubMed)
    Show all 2 references for ABIN672111

  5. Human Polyclonal LDLR Primary Antibody for FACS, IHC (fro) - ABIN113461 : Eden, Patel, Sun, Burden, Themis, Edwards, Lee, Neuwirth, Naoumova, Soutar: Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1. in The Journal of clinical investigation 2002 (PubMed)
    Show all 2 references for ABIN113461

  6. Human Monoclonal LDLR Primary Antibody for ELISA - ABIN1996141 : Pinson, Brennan, Monkley, Avery, Skarnes: An LDL-receptor-related protein mediates Wnt signalling in mice. in Nature 2000 (PubMed)

  7. Human Polyclonal LDLR Primary Antibody for FACS - ABIN113462 : Akazawa, Date, Morikawa, Murayama, Miyamoto, Kaga, Barth, Baumert, Dubuisson, Wakita: CD81 expression is important for the permissiveness of Huh7 cell clones for heterogeneous hepatitis C virus infection. in Journal of virology 2007 (PubMed)

  8. Human Monoclonal LDLR Primary Antibody for ELISA, WB - ABIN561655 : Ueno, Wu, Nakagawa, Nagai, Onodera, Huang, Kusaka, Kanenishi, Sakamoto: The expression of LDL receptor in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model. in Histochemistry and cell biology 2010 (PubMed)

  9. Human Polyclonal LDLR Primary Antibody for FACS, WB - ABIN652907 : Brown, Goldstein: Receptor-mediated endocytosis: insights from the lipoprotein receptor system. in Proceedings of the National Academy of Sciences of the United States of America 1979 (PubMed)

  10. Human Polyclonal LDLR Primary Antibody for EIA, IHC (p) - ABIN500146 : Li, Cam, Bu: Low-density lipoprotein receptor family: endocytosis and signal transduction. in Molecular neurobiology 2001 (PubMed)

More Antibodies against LDLR Interaction Partners

Human Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Specifically, loss of IDOL (show MYLIP Antibodies) increases LDLR distribution in the hepatic cell, and subsequently reduces serum LDL-C levels in dyslipidemic patients.

  2. de novo mutation of the LDL receptor gene as the cause of familial hypercholesterolemia

  3. A recurrent frameshift mutation in LDLR gene causing familial hypercholesterolemia was identified in 9 probands and their relatives.

  4. LDL receptor gene polymorphisms play a role in the treatment response of hepatitis C and the modulation of disease progression in Egyptians infected with chronic HCV.

  5. This study aimed to perform a systematic review of LDLR mutations in China.

  6. miR (show MLXIP Antibodies)-185 controls cholesterol homeostasis as a key posttranscriptional LDLR modulator in hepatic cells, providing novel insight into the regulatory mechanism for LDLR expression and the anti-atherosclerosis effect of miR (show MLXIP Antibodies)-185-inhibitor.

  7. Three polymorphisms in the 3' UTR (show UTS2R Antibodies) region of LDLR, c.*52G>A, c.*504G>A, and c.*773A>G, and two at the 5' UTR (show UTS2R Antibodies) region of PCSK9 (show PCSK9 Antibodies), c.-3383C>G and c.-2063A>G, were associated with response to Armolipid Plus

  8. in well characterized FCHL (show USF1 Antibodies) individuals, variants in LDLR and LPL (show LCP1 Antibodies) provide a small contribution to dyslipidemia

  9. MicroRNA-27a has a role in decreasing the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis

  10. Data suggest inducible expression of IDOL (show MYLIP Antibodies) is subject to robust, rapid regulation by process that is sensitive to deubiquitinase inhibition in human/mouse cell lines and primary human cells; transcriptional induction of IDOL (show MYLIP Antibodies) leads to degradation of LDLR.

Cow (Bovine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE (show APOE Antibodies), MTP (show MTTP Antibodies), and LDLR, thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

Mouse (Murine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Neurometabolic roles of ApoE (show APOE Antibodies) and Ldl-R in mouse brain.

  2. Absence of Elovl6 (show ELOVL6 Antibodies) attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(-/-) mouse model.

  3. Suggest Idol (show MYLIP Antibodies) as a gatekeeper of LDLR-dependent ApoE (show APOE Antibodies) and Abeta (show APP Antibodies) clearance in the brain and a potential enzyme target for therapeutic intervention in Alzheimer disease.

  4. binding of PCSK9 (show PCSK9 Antibodies) to GRP94 (show HSP90B1 Antibodies) protects LDLR from degradation likely by preventing early binding of PCSK9 (show PCSK9 Antibodies) to LDLR

  5. Short-term modulation of miR (show MLXIP Antibodies)-27b expression in wild-type mice regulates hepatic LDLR and ABCA1 (show ABCA1 Antibodies) expression but does not influence plasma and hepatic lipid levels.

  6. miR (show MLXIP Antibodies)-185 controls cholesterol homeostasis as a key posttranscriptional LDLR modulator in hepatic cells, providing novel insight into the regulatory mechanism for LDLR expression and the anti-atherosclerosis effect of miR (show MLXIP Antibodies)-185-inhibitor.

  7. The absence of PCSK9 (show PCSK9 Antibodies) results in a sex- and tissue-specific subcellular distribution of the LDLR and VLDLR (show VLDLR Antibodies), which is determined by estradiol levels.

  8. In the present study, we examined the effects of H2 on atherosclerotic plaque stability and the underlying mechanisms in low-density lipoprotein receptor-knockout (LDLR-/-) mice and macrophage-derived foam cell models.

  9. Targeted deletion of ChREBP (show MLXIPL Antibodies) in bone marrow cells resulted in accelerated atherosclerosis progression in Ldlr-/- mice with increased monocytosis, lesional macrophage accumulation, and plaque necrosis.

  10. Blockade of Tim-1 (show HAVCR1 Antibodies) and Tim-4 (show TIMD4 Antibodies) enhances atherosclerosis in LDL receptor knockout mice.

Pig (Porcine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. The LDLR gene should be a candidate causative gene for LDL-cholesterol and total cholesterol in pigs, but heterogeneity exists in different populations.

  2. KLF13 (show KLF13 Antibodies) and SREBP-Sp1 (show SP1 Antibodies) activation interact to regulate low density lipoprotein receptor promoter function

  3. found association between genotypes for LDLR and APOB (show APOB Antibodies) polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

LDLR Antigen Profile

Protein Summary

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with LDLR

  • low density lipoprotein receptor (ldlr) antibody
  • low density lipoprotein receptor (LDLR) antibody
  • low density lipoprotein receptor (Ldlr) antibody
  • low density protein receptor (LOC443535) antibody
  • FH antibody
  • FHC antibody
  • Hlb301 antibody
  • LDLA antibody
  • LDLCQ2 antibody
  • LDLRA antibody

Protein level used designations for LDLR

low-density lipoprotein receptor , LDL receptor , low-density lipoprotein receptor class A domain-containing protein 3 , low density lipoprotein receptor (familial hypercholesterolemia)

GENE ID SPECIES
387529 Danio rerio
3949 Homo sapiens
281276 Bos taurus
100009086 Oryctolagus cuniculus
16835 Mus musculus
300438 Rattus norvegicus
100724238 Cavia porcellus
396801 Sus scrofa
100683160 Canis lupus familiaris
395103 Gallus gallus
100689399 Cricetulus griseus
443535 Ovis aries
Selected quality suppliers for anti-LDLR (LDLR) Antibodies
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