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anti-Low Density Lipoprotein Receptor (LDLR) Antibodies

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Additionally we are shipping LDLR Kits (45) and LDLR Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LDLR 3949 P01130
LDLR 16835 P35951
LDLR 300438 P35952
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Top anti-LDLR Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of LDLR Antibody (Center) (ABIN652907) in mouse ... LDLR Antibody (Center) (ABIN652907) FC analysis of MCF-7 cells (bottom... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of LDLR expression in Jurkat cell (Lane 1) and 3... 100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Chicken Un-conjugated EIA, IHC (p), WB Immunohistochemistry of LDL-R in human liver tissue with this product ... Western blot analysis of LDL-R in human liver tissue lysate with this ... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled An... Human colon lysates probed with Anti LDL Receptor Polyclonal Antibody,... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Cow Mouse Un-conjugated FACS, IF, WB   50 μg Log in to see 6 to 8 Days
$357.50
Details
Cow Mouse Biotin FACS, IHC (fro), WB   1 mL Log in to see 6 to 8 Days
$467.50
Details
Human Rabbit FITC FACS Profile of anti-Human LDLR reactivity on HepG2 cells analyzed by flow ... 50 Tests Log in to see 16 Days
$198.00
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated FACS, IHC (fro), WB   0.25 mL Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LDLR is approximately 0.3ng... Western Blot analysis of LDLR expression in transfected 293T cell line... 100 μg Log in to see 9 Days
$430.00
Details

LDLR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-LDLR Antibodies

  1. Cow (Bovine) Polyclonal LDLR Primary Antibody for WB - ABIN223504 : Dong, Wu, Li, Kraemer, Adeli, Seidah, Park, Liu: Strong induction of PCSK9 gene expression through HNF1{alpha} and SREBP2: Mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. in Journal of lipid research 2010 (PubMed)
    Show all 7 references for ABIN223504

  2. Cow (Bovine) Monoclonal LDLR Primary Antibody for FACS, IHC (fro) - ABIN112188 : Beisiegel, Schneider, Brown, Goldstein: Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia. in The Journal of biological chemistry 1982 (PubMed)
    Show all 4 references for ABIN112188

  3. Cow (Bovine) Monoclonal LDLR Primary Antibody for FACS, IF - ABIN112187 : Beisiegel, Schneider, Goldstein, Anderson, Brown: Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia. in The Journal of biological chemistry 1982 (PubMed)
    Show all 4 references for ABIN112187

  4. Human Polyclonal LDLR Primary Antibody for IF (p), IHC (p) - ABIN672111 : Wu, He, Wang, Xue, Ning, Zou, Ye, Li, Wang, Pang: The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. in Phytomedicine : international journal of phytotherapy and phytopharmacology 2014 (PubMed)
    Show all 2 references for ABIN672111

  5. Human Polyclonal LDLR Primary Antibody for FACS, IHC (fro) - ABIN113461 : Eden, Patel, Sun, Burden, Themis, Edwards, Lee, Neuwirth, Naoumova, Soutar: Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1. in The Journal of clinical investigation 2002 (PubMed)
    Show all 2 references for ABIN113461

  6. Human Monoclonal LDLR Primary Antibody for ELISA - ABIN1996141 : Pinson, Brennan, Monkley, Avery, Skarnes: An LDL-receptor-related protein mediates Wnt signalling in mice. in Nature 2000 (PubMed)

  7. Human Polyclonal LDLR Primary Antibody for EIA, IHC (p) - ABIN500146 : Li, Cam, Bu: Low-density lipoprotein receptor family: endocytosis and signal transduction. in Molecular neurobiology 2001 (PubMed)

  8. Human Polyclonal LDLR Primary Antibody for FACS, WB - ABIN652907 : Brown, Goldstein: Receptor-mediated endocytosis: insights from the lipoprotein receptor system. in Proceedings of the National Academy of Sciences of the United States of America 1979 (PubMed)

  9. Human Monoclonal LDLR Primary Antibody for ELISA, WB - ABIN561655 : Ueno, Wu, Nakagawa, Nagai, Onodera, Huang, Kusaka, Kanenishi, Sakamoto: The expression of LDL receptor in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model. in Histochemistry and cell biology 2010 (PubMed)

More Antibodies against LDLR Interaction Partners

Human Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Three polymorphisms in the 3' UTR (show UTS2R Antibodies) region of LDLR, c.*52G>A, c.*504G>A, and c.*773A>G, and two at the 5' UTR (show UTS2R Antibodies) region of PCSK9 (show PCSK9 Antibodies), c.-3383C>G and c.-2063A>G, were associated with response to Armolipid Plus

  2. in well characterized FCHL (show USF1 Antibodies) individuals, variants in LDLR and LPL (show LCP1 Antibodies) provide a small contribution to dyslipidemia

  3. MicroRNA-27a has a role in decreasing the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis

  4. Data suggest inducible expression of IDOL (show MYLIP Antibodies) is subject to robust, rapid regulation by process that is sensitive to deubiquitinase inhibition in human/mouse cell lines and primary human cells; transcriptional induction of IDOL (show MYLIP Antibodies) leads to degradation of LDLR.

  5. patients with a null LDLR mutation had: higher baseline LDL-C, higher LDL-C after drug therapy--{REVIEW}

  6. analysis of LDLR mutations in familial hypercholesterolemia patients in the Saudi population

  7. LDLR gene synonymous mutation c.1813C>T results in mRNA splicing variation in a kindred with familial hypercholesterolaemia

  8. Mutation p.L799R in the LDLR should be considered a member of a separate class of Familial Hypercholesterolemia-causing mutations that affects the insertion of the LDLR in the cell membrane.

  9. LDLR gene is a new susceptibility gene associated with the development of thrombosis in antiphospholipid antibodies carriers.

  10. Identify USP2 (show USP2 Antibodies) as a novel regulator of lipoprotein clearance owing to its ability to control ubiquitylation-dependent degradation of the LDLR by IDOL (show MYLIP Antibodies).

Cow (Bovine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. Nonesterified fatty acids significantly inhibit the expression of ApoB100 (show APOB Antibodies), ApoE (show APOE Antibodies), MTP (show MTTP Antibodies), and LDLR, thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.

Mouse (Murine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. In the present study, we examined the effects of H2 on atherosclerotic plaque stability and the underlying mechanisms in low-density lipoprotein receptor-knockout (LDLR-/-) mice and macrophage-derived foam cell models.

  2. Targeted deletion of ChREBP (show MLXIPL Antibodies) in bone marrow cells resulted in accelerated atherosclerosis progression in Ldlr-/- mice with increased monocytosis, lesional macrophage accumulation, and plaque necrosis.

  3. Blockade of Tim-1 (show HAVCR1 Antibodies) and Tim-4 (show TIMD4 Antibodies) enhances atherosclerosis in LDL receptor knockout mice.

  4. Reveal a previously unappreciated strong link between adipose tissue and LDLR in plasma cholesterol metabolism in LDLR knockout mice.

  5. The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB (show APOB Antibodies)(tm25gy) LDLr(tm1Her) mice, expressing only ApoB100 (show APOB Antibodies) and deficient in the low density lipoprotein receptor.

  6. The Liver Clock Controls Cholesterol Homeostasis through Trib1 (show TRIB1 Antibodies) Protein-mediated Regulation of PCSK9 (show PCSK9 Antibodies)/Low Density Lipoprotein Receptor (LDLR) Axis.

  7. SAA1 (show SAA1 Antibodies)/2 produced by macrophages promotes early lesion formation in the ascending aorta in LDLR knockout mice.

  8. to examine potential mechanisms by which murine norovirus influences the atherosclerosis disease process, we fed Ldlr(-/-) mice an atherogenic diet

  9. Fibronectin (show FN1 Antibodies) extra domain A stabilises atherosclerotic plaques in apolipoprotein E (show APOE Antibodies) and in LDL-receptor-deficient mice.

  10. Porphyromonas gingivalis infection in the oral cavity can lead to significant TLR2 (show TLR2 Antibodies)-CD36 (show CD36 Antibodies)/SR-B2 dependent IL1ss release.

Pig (Porcine) Low Density Lipoprotein Receptor (LDLR) interaction partners

  1. The LDLR gene should be a candidate causative gene for LDL-cholesterol and total cholesterol in pigs, but heterogeneity exists in different populations.

  2. KLF13 (show KLF13 Antibodies) and SREBP-Sp1 (show SP1 Antibodies) activation interact to regulate low density lipoprotein receptor promoter function

  3. found association between genotypes for LDLR and APOB (show APOB Antibodies) polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms

LDLR Antigen Profile

Protein Summary

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with LDLR

  • low density lipoprotein receptor (ldlr) antibody
  • low density lipoprotein receptor (LDLR) antibody
  • low density lipoprotein receptor (Ldlr) antibody
  • low density protein receptor (LOC443535) antibody
  • FH antibody
  • FHC antibody
  • Hlb301 antibody
  • LDLA antibody
  • LDLCQ2 antibody
  • LDLRA antibody

Protein level used designations for LDLR

low-density lipoprotein receptor , LDL receptor , low-density lipoprotein receptor class A domain-containing protein 3 , low density lipoprotein receptor (familial hypercholesterolemia)

GENE ID SPECIES
387529 Danio rerio
3949 Homo sapiens
281276 Bos taurus
100009086 Oryctolagus cuniculus
16835 Mus musculus
300438 Rattus norvegicus
100724238 Cavia porcellus
396801 Sus scrofa
100683160 Canis lupus familiaris
395103 Gallus gallus
100689399 Cricetulus griseus
443535 Ovis aries
Selected quality suppliers for anti-LDLR (LDLR) Antibodies
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