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anti-Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) Antibodies

LRP8 encodes a member of the low density lipoprotein receptor (LDLR) family. Additionally we are shipping LRP8 Proteins (10) and LRP8 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LRP8 7804 Q14114
LRP8 16975  
LRP8 362558  
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Top anti-LRP8 Antibodies at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-LRP8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-LRP8 Pab (ABIN390101) is used in Western blot to detect LRP8 in placenta cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged LRP8 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (35.42 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded chicken lung labeled with Anti ApoER2 Polyclonal Antibody, Unconjugated (ABIN719426) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-ApoER2 Polyclonal Antibody, Unconjugated (ABIN719426) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details

LRP8 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-LRP8 Antibodies

  1. Human Polyclonal LRP8 Primary Antibody for EIA, IHC (p) - ABIN358640 : Li, Kypreos, Zanni, Zannis: Domains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brain. in Biochemistry 2003 (PubMed)
    Show all 4 references for ABIN358640

  2. Chicken Polyclonal LRP8 Primary Antibody for IHC, WB - ABIN2781990 : Hoe, Minami, Makarova, Lee, Hyman, Matsuoka, Rebeck: Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing. in The Journal of biological chemistry 2008 (PubMed)

  3. Human Polyclonal LRP8 Primary Antibody for ELISA, WB - ABIN1452111 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)

  4. Human Monoclonal LRP8 Primary Antibody for ELISA, WB - ABIN563474 : Liu, Wu, Baysarowich, Kavana, Addona, Bierilo, Mudgett, Pavlovic, Sitlani, Renger, Hubbard, Fisher, Zerbinatti: PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain. in Journal of lipid research 2010 (PubMed)

More Antibodies against LRP8 Interaction Partners

Human Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) interaction partners

  1. ApoER2 contributes cooperatively with endothelial cell protein C receptor (show PROCR Antibodies) and protease activated receptor 1 (show F2R Antibodies) to APC (show APC Antibodies)-initiated endothelial antiapoptotic and barrier protective signaling.

  2. two SNPs (rs3737984 and rs2297660) in ApoER2 gene had significant association with dyslipidemia in Thai ethnic

  3. A novel TACGC risk haplotype in the LRP8 gene that is present in patients with CAD (show CAD Antibodies) and MI but not in normal controls.

  4. results of this study demonstrated the presence of reelin (show RELN Antibodies), its receptors VLDLR (show VLDLR Antibodies) and ApoER2 as well as Dab1 (show DAB1 Antibodies) in the ENS and might indicate a novel role of the reelin (show RELN Antibodies) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.

  5. Data suggest that PS1 (show PSEN1 Antibodies)/gamma-secretase-dependent processing of the reelin (show RELN Antibodies) receptor ApoER2 inhibits reelin (show RELN Antibodies) expression and may regulate its signaling.

  6. ectopic expression of HIC1 (show HIC1 Antibodies) in U2OS and MDA-MB-231 cell lines decreases expression of the ApoER2 and VLDLR (show VLDLR Antibodies) genes, encoding two canonical tyrosine kinase (show TXK Antibodies) receptors for Reelin (show RELN Antibodies).

  7. By incorporating the information from bioinformatics and RNA expression analyses, we identified at least two of the most promising risk genes for alcohol dependence: APOER2 and UBAP2 (show UBAP2 Antibodies)

  8. TCCGC haplotype at the 3'-terminal block of the LRP8 gene confers a protective role in the development of familial and early-onset coronary artery disease and/or myocardial infarction.

  9. In a Chinese unrelated Han population, variants within the LRP8 gene do not convey the risk of developing Parkinson's disease.

  10. results identify LRP8 as a novel positive factor of canonical Wnt signa (show WNT2 Antibodies)ling pathway

Mouse (Murine) Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) interaction partners

  1. reveals a novel function for Reelin (show RELN Antibodies)/ApoER2 in peripheral nervous system, inducing cell migration of Schwann cells, a process relevant for peripheral nervous system development and regeneration

  2. total levels of ApoER2 and surface levels of ApoER2 are increased by active Fyn (show FYN Antibodies)

  3. This study demonstrated that ApoER2 is expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.

  4. This study demonistrated that LRP8-Reelin (show RELN Antibodies)-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation in mice.

  5. Apoer2 lacking exon 16, the O-linked sugar domain, altered the proteolytic processing and abundance of Apoer2 in cells and synapse number and function in mice, hippocampal spine density, LTP (show SCP2 Antibodies), and cued fear learning.

  6. genetic variants of apoE (show APOE Antibodies) and ApoER2 impact cardiovascular health by differentially modulating endothelial function.

  7. Study shows that the levels of hippocampal ApoE (show APOE Antibodies) receptors Lrp1 (show LRP1 Antibodies) and Apoer2 in vivo are affected isoform specifically by ApoE4 and that the type of receptor affected is context dependent

  8. Tandem Sepp1 (show SEPP1 Antibodies)-apoER2 interactions supply selenium for maintenance of brain neurons both at the blood-brain barrier and within the brain. Sepp1 (show SEPP1 Antibodies) inside the blood-brain barrier is taken up by neurons via apoER2, concentrating brain selenium in them.

  9. data demonstrate that several multivalent ligands for ApoER2 induce clustering in transfected cells and primary neurons and that these complexes included other synaptic molecules, such as APP (show APP Antibodies) and PSD-95 (show DLG4 Antibodies)

  10. Apolipoprotein E receptor-2 deficiency enhances macrophage susceptibility to lipid accumulation and cell death to augment atherosclerotic plaque progression and necrosis.

Cow (Bovine) Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) interaction partners

  1. genetic variants of apoE (show APOE Antibodies) and ApoER2 impact cardiovascular health by differentially modulating endothelial function.[ApoER2]

  2. the differential expression patterns of LRP8 mRNA during final follicular growth and ovulation

LRP8 Antigen Profile

Protein Summary

This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with LRP8

  • low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (LRP8) antibody
  • low density lipoprotein receptor-related protein 8 (LOC100219357) antibody
  • low density lipoprotein receptor-related protein 8 (LOC100345692) antibody
  • low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (Lrp8) antibody
  • 4932703M08Rik antibody
  • AA921429 antibody
  • AI848122 antibody
  • ApoER2 antibody
  • HSZ75190 antibody
  • LR8B antibody
  • LRP-8 antibody
  • LRP8 antibody
  • MCI1 antibody

Protein level used designations for LRP8

low density lipoprotein receptor-related protein 8, apolipoprotein e receptor , low density lipoprotein receptor-related protein 8 , low-density lipoprotein receptor-related protein 8-like , ApoE receptor 2 , low-density lipoprotein receptor-related protein 8 , apolipoprotein E receptor 2 , low density lipoprotein receptor relative, 8 ligand binding repeats, brain , LRP-8

GENE ID SPECIES
456865 Pan troglodytes
100060928 Equus caballus
100219357 Taeniopygia guttata
100345692 Oryctolagus cuniculus
100470074 Ailuropoda melanoleuca
100604448 Nomascus leucogenys
7804 Homo sapiens
16975 Mus musculus
396102 Gallus gallus
489584 Canis lupus familiaris
407179 Bos taurus
362558 Rattus norvegicus
100187577 Sus scrofa
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