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Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.. Additionally we are shipping Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 Proteins (23) and Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 Kits (7) and many more products for this protein.
Showing 10 out of 94 products:
Human Polyclonal LRPAP1 Primary Antibody for EIA, WB - ABIN453733
Lisi, Botta, Pinchera, Di Cosmo, Perri, De Marco, Menconi, Marinò: Sequencing of the entire coding region of the receptor associated protein (RAP) in patients with primary hypothyroidism of unknown origin. in Journal of endocrinological investigation 2007
Show all 2 references for ABIN453733
Chicken Polyclonal LRPAP1 Primary Antibody for IHC, WB - ABIN2782171
Wu, Migliorini, Walsh, Yu, Strickland, Wang: NMR structural studies of domain 1 of receptor-associated protein. in Journal of biomolecular NMR 2004
Human Monoclonal LRPAP1 Primary Antibody for IHC (fro), IF - ABIN112189
Kounnas, Argraves, Strickland: The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330. in The Journal of biological chemistry 1992
The clinical and biometric features we describe in this report characterize LRPAP1-related high myopia and should raise suspicion for mutations in the gene.
The inhibition caused by reagents that prevented the activation of Rap was reversed by mobilizing intracellular calcium pharmacologically, whereas that caused by acrosome reaction inhibitors that impeded Rab3 (show RAB3A Antibodies)'s binding to GTP (show AK3 Antibodies) was not.
The LRPAP1 I allelic variant may be considered a candidate gene for PD, predominantly in patients having the APOE (show APOE Antibodies) epsilon4 allelic variant.
RAP inhibited light chain (LC)endocytosis by approximately 88% and ameliorated LC-induced cytokine responses and epithelial-to-mesenchymal transformation in human proximal tubular cells.
Mutations in LRPAP1 are associated with severe myopia in humans.
Data indicate that the region of complement-type repeats 2-5 in LDLR (show LDLR Antibodies) was identified as the binding site for FVIII (show F8 Antibodies) and for alpha-2-macroglobulin receptor-associated protein (RAP).
LRP1 (show LRP1 Antibodies)-C/T, A2M (show A2M Antibodies)-Ile/Val and APOE (show APOE Antibodies)-epsilon 2/epsilon 3/epsilon 4 polymorphisms are associated with AD.
Findings reveal that RAP is a novel Abeta (show APP Antibodies)-binding protein that promotes cellular internalization of Abeta (show APP Antibodies).
Adenoviral-mediated expression of human receptor-asociated protein RAP in a murine model of von Willebrand disease results in a continuous rise in FVIII (show F8 Antibodies) over 6 days.
Allosteric modulation of ligand binding to low density lipoprotein receptor (show LDLR Antibodies)-related protein (show LRP1 Antibodies) by the receptor-associated protein (show BCAP31 Antibodies) requires critical lysine residues within its carboxyl-terminal domain
RAP deficiency attenuated atherosclerosis without influencing abdominal aortic aneurysms in hypercholesterolemic mice infused with angiotensin II.
In RAP-deficient mice megalin expression was strongly reduced and restricted to a subapical localization and NaP(i)-IIa protein distribution and abundance in the kidney was not altered.
the His-sRAP (show SRA1 Antibodies)-induced acceleration of megalin (show LRP2 Antibodies)-mediated endocytosis causes phosphaturia via altered subcellular distribution of NaPi-II [39-kD receptor-associated protein (RAP)]
Results suggest that receptor-associated protein (show BCAP31 Antibodies) is required for the establishment of thyroglobulin (show TG Antibodies) reservoirs, but its absence does not affect hormone secretion.
RAP binds to LPL (show LPL Antibodies) with high affinity both in purified systems and cell extracts and RAP-deficient adipocytes secrete poorly assembled LPL (show LPL Antibodies)
RAP is expressed by thyrocytes in a TSH-dependent manner, both in cultured thyroid cells and in vivo
Disruption of the RAP gene determines not only thyroid abnormalities, but also a severe defect of megalin (show LRP2 Antibodies) expression and function in the kidney.
Receptor-associated protein (RAP) plays a central role in modulating Abeta (show APP Antibodies) deposition in APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies) transgenic mice
Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
alpha-2-macroglobulin receptor-associated protein
, low density lipoprotein receptor-related protein associated protein 1
, alpha-2-macroglobulin receptor-associated protein 1
, lipoprotein receptor associated protein
, low density lipoprotein receptor-related protein-associated protein 1
, low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
, receptor-associated protein
, gp330-binding 45 kDa protein
, Alpha-2-macroglobulin receptor-associated protein precursor (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) (Heparin binding protein-44) (HBP-44)
, heparin-binding protein 44
, low density lipoprotein receptor related protein, associated protein 1