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LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. Additionally we are shipping Luteinizing Hormone/choriogonadotropin Receptor Kits (8) and Luteinizing Hormone/choriogonadotropin Receptor Proteins (8) and many more products for this protein.
Showing 10 out of 100 products:
Human Polyclonal LHCGR Primary Antibody for IF (p), IHC (p) - ABIN873328
Yang, Dou, Zhang, Gu, Lv, DU, Ba, Mu, Lu: Increased 3β-hydroxysteroid dehydrogenase 2 and 17α-hydroxylase activities in a virilized adolescent female with adrenal adenoma: A case report. in Experimental and therapeutic medicine 2016
Human Polyclonal LHCGR Primary Antibody for IHC (p) - ABIN122503
Sand, Bergvall, Ekblad, DAmato, Ohlsson: Expression and distribution of GnRH, LH, and FSH and their receptors in gastrointestinal tract of man and rat. in Regulatory peptides 2013
Rat (Rattus) Polyclonal LHCGR Primary Antibody for WB - ABIN336206
Berndt, Perrier dHauterive, Blacher, Péqueux, Lorquet, Munaut, Applanat, Hervé, Lamandé, Corvol, van den Brûle, Frankenne, Poutanen, Huhtaniemi, Geenen, Noël, Foidart: Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006
Human Polyclonal LHCGR Primary Antibody for ELISA, WB - ABIN190901
Bukovsky, Indrapichate, Fujiwara, Cekanova, Ayala, Dominguez, Caudle, Wimalsena, Elder, Copas, Foster, Fernando, Henley, Upadhyaya et al.: Multiple luteinizing hormone receptor (LHR) protein variants, interspecies reactivity of anti-LHR mAb clone 3B5, subcellular localization of LHR in human placenta, pelvic floor and brain, and ... in Reproductive biology and endocrinology : RB&E 2004
Data show that double mutation of follicle-stimulating hormone receptor (fshr (show FSHR Antibodies)) and luteinizing hormone receptor (lhcgr) resulted in infertile males
Data show for the first time in a vertebrate species that Leydig cells as well as Sertoli cells express the mRNAs for both fshr (show FSHR Antibodies) and lhcgr.
The ALDH1 (show ALDH1A1 Antibodies) activity and sphere forming ability of CD44 (show CD44 Antibodies)(high) /ALDH1 (show ALDH1A1 Antibodies)(high) cells was significantly inhibited by GSK3beta (show GSK3b Antibodies) knockdown. On the other hand, CD44 (show CD44 Antibodies)(high) /ALDH1 (show ALDH1A1 Antibodies)(low) cells exhibited high epidermal growth factor receptor (EGFR (show EGFR Antibodies)) expression and increased cell growth.
Analysis of KRAS mutation combined with immunohistochemical expression of CD44 (show CD44 Antibodies) and CD166 (show ALCAM Antibodies) identified subgroups of patients with colon adenocarcinoma at higher risk of lymph node involvement by the tumor and development of liver and lung metastasis.
Mutation in the LHCGR gene is associated with Testotoxicosis.
Study shows that CD44 (show CD44 Antibodies) is an important regulator of glucose metabolism in small cell neuroendocrine carcinoma.
the authors investigated the ability of two hyaluronan-based nanoparticles targeting CD44 (show CD44 Antibodies) receptors to home in on lung cancer cells in an in-vivo orthotropic model. The preferential uptake of smaller sized nanoparticles via intravenous route has further enhanced the existing knowledge of future drug designs.
The luteinizing hormone/human chorionic gonadotrophin receptor (LHCGR) variant N312S and the follicle-stimulating hormone receptor (FSHR (show FSHR Antibodies)) variant N680S can be utilized for the prediction of pregnancy chances in women undergoing IVF (show SCN5A Antibodies).
Although LCN2 (show LCN2 Antibodies) increased intracellular iron concentrations, LCN2 (show LCN2 Antibodies)-induced GSH may catalyze and override oxidative stress via CD44 (show CD44 Antibodies) and xCT (show SLC7A11 Antibodies), and subsequently enhance the survival of clear cell carcinoma tumor cells in oxidative stress-rich environment.
loss of the CD44 (show CD44 Antibodies) expression plays role in lymphovascular permeation and metastasis and it can be hypothesized that its reexpression at metastatic site may play a role in homing of tumor cells
CD44 and CD133 might participate in early-stage endometrial cancer carcinogenesis
Data indicate two patients with peripheral precocious puberty and an activating mutation in the luteinizing hormone (LH))/choriogonadotropin receptor (LHCGR) gene.
Data suggest that persistent cAMP signals from internalized luteinizing hormone receptor (LH receptors) contribute to transmitting LH effects inside follicle cells and ultimately to the oocyte.
Demonstrate the presence of LH receptors. Activation resulted in a dose-dependent increase in glucose-induced release of insulin (show INS Antibodies).
LHCGR signaling in regulating the Ahr (show AHR Antibodies) message involves protein kinase A pathway and is attributable to decreased transcription rate.
Data from mutant mouse strain (gain-of-function mutation in LHR, D578G; most common mutation found in familial male-limited precocious puberty) confirm that LHR is critical for male steroidogenesis, gametogenesis, and Leydig cell development.
LH/hCG (show CGA Antibodies) tightly up-regulates MKP-3 (show DUSP6 Antibodies) which in turn, dephosphorylates ERK1/2 (show MAPK1/3 Antibodies) and drives p21 (show D4S234E Antibodies) expression.
Data suggest that Lhcgr in endometrium and luteinizing hormone in blastocyst are involved in embryo/blastocyst implantation; expression of Lhcgr is up-regulated in endometrial epithelium in estrus cycle at time of implantation readiness (estrus).
Through the LHR, LH/hCG (show CGA Antibodies) tightly regulates MKP-2 (show DUSP4 Antibodies) expression, which modulates the induction of CYP11A1 (show CYP11A1 Antibodies) by 8Br-cAMP.
Expression of LH receptor in nonpregnant mouse endometrium.
Testicular CYP1B1 (show CYP1B1 Antibodies) expression is regulated by LH through a PRKA (show Akap6 Antibodies)-mediated pathway.
Role of RXFP2 (show RXFP2 Antibodies) in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice.
The outcomes of the present study support a dynamic multi-facetted regulation of LHR during pre-translation.
expression of LHR mRNA in bovine granulosa cells is established after follicle deviation, and the lower abundance of LRBP (show MVK Antibodies) mRNA after the expected time of deviation may contribute to greater expression of LHR in the bovine dominant follicle
These results suggested an acute regulation of INSL3 (show INSL3 Antibodies) by luteinizing hormone (LH) because INSL3 (show INSL3 Antibodies) concentrations increased immediately after endogenous and exogenous LH stimulation.
INVESTIGATION OF STAT5A (show STAT5A Antibodies), FSHR (show FSHR Antibodies) AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS
These findings strongly support the concept that IGF-1 (show IGF1 Antibodies) upregulates LHR expression in granulosa cells and that IGF-1 (show IGF1 Antibodies) is required for determining which follicle becomes dominant and acquires ovulatory capacity.
LHCGR mRNA expression in granulosa cells was significantly higher in large antral follicles than in cysts, and not detected in granulosa cells of small and medium antral follicles.
The luteinizing hormone receptor [LHR] splicing pattern is complex in bovine Leydig cells, and expression of full-length LHR and isoforms A and B changes when induced with LH.
The LHCGR gene is a potential marker for superovulation response and can be used to predict the most appropriate dose of FSH (show BRD2 Antibodies) for superovulation in Chinese Holstein cows.
Dominant follicles experience a reduction in FSH (show BRD2 Antibodies) dependence (diminished expression of FSHR (show FSHR Antibodies)), but acquire increased LH dependence (enhanced expression of LHCGR) as they grow during the low FSH (show BRD2 Antibodies) milieu of follicular waves.
Three single nucleotide polymorphisms in LHCGR were significantly associated with variations in cattle fertility and production traits.
In porcine ovaries, MAb found 6 distinct LHR bands migrating at approximately 92, 80, 68, 59, 52 & 48 kDa. There is a possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders & Alzheimer's disease.
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
luteinizing hormone receptor
, lutropin-choriogonadotropic hormone receptor
, luteinizing hormone/choriogonadotropin receptor
, lutropin-choriogonadotropic hormone receptor-like
, Lutropin-choriogonadotropic hormone receptor
, CD44 antigen
, GP90 lymphocyte homing/adhesion receptor
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, extracellular matrix receptor III
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, hyaluronate receptor
, phagocytic glycoprotein 1
, hypergonadotropic hypogonadism
, lutropin/choriogonadotropin receptor
, LH receptor
, luteinizing hormone receptor 2 protein
, luteinizing hormone receptor precursor variant 1
, luteinizing hormone receptor precursor variant 2
, lutropin-choriogonadotropin receptor