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anti-Ly6/neurotoxin 1 (LYNX1) Antibodies

LYNX1 encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characterist. Additionally we are shipping Ly6/neurotoxin 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LYNX1 66004 Q9BZG9
LYNX1 23936 Q9WVC2
Anti-Rat LYNX1 LYNX1 300018  
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Top anti-Ly6/neurotoxin 1 Antibodies at

Showing 3 out of 3 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: LYNX1 Antibody [NBP1-80739] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Western Blot: LYNX1 Antibody [NBP1-80739] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY411399) 0.1 mL Log in to see 8 to 11 Days

LYNX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Mouse (Murine)

More Antibodies against Ly6/neurotoxin 1 Interaction Partners

Human Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. These findings provide new insights into the acetylcholine receptor (show CHRNA1 Antibodies)-mediated regulatory mechanism of SLURP-2 expression in keratinocytes.

  2. These studies suggest that lynx1 is a potential target both for development of drugs that may limit lung cancer growth as well as for drugs that may be effective for asthma or COPD (show ARCN1 Antibodies) treatment.

  3. This epigenome-wide DNA methylation (show HELLS Antibodies) analysis in postmortem hippocampus and prefrontal cortex specimens confirmed LYNX1 DNA methylation (show HELLS Antibodies) profiles in major depression.

  4. SLURP-2 downregulated TNFalpha (show TNF Antibodies) and IFNgamma R in T-cells and reduced IL-6 (show IL6 Antibodies) production by macrophage

  5. Micromolar affinities and fast washout rates measured for ws-LYNX1 and its mutants are in contrast to nanomolar affinities and irreversibility of binding for alpha-bungarotoxin and similar snake alpha-neurotoxins also targeting alpha7 nAChR (show CHRNA7 Antibodies).

  6. Computer modeling, based on ws-LYNX1 NMR structure and AChBP x-ray structure, revealed a possible mode of ws-LYNX1 binding.

  7. These results indicated that SLURP-2 competes with acetylcholine predominantly at the alpha3 nAChR (show CHRNA4 Antibodies), and that receptor ligation with SLURP-2 delays keratinocyte differentiation and prevents apoptosis.

  8. LY-6K (show Ly6k Antibodies),a novel member protein of the Ly-6/uPAR (show PLAUR Antibodies) superfamily, is a significant new molecular marker for diagnosis and gene therapy in patients with breast cancer.

  9. anti-tumorigenic activities of SLURP-1 (show SLURP1 Antibodies) and -2 were demonstrated both in vitro and in vivo.

  10. decreased Lynx1 is associated with squamous cell lung carcinoma

Mouse (Murine) Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. tPA (show PLAT Antibodies) activity in V1 can be unmasked following 4 d of monocular deprivation when mice older than 2 months are raised in standard cages by the genetic removal of Lynx1, a negative regulator of adult plasticity.

  2. lynx1 KO animals over 1 year of age have clear ultrastructural differences in the striatum.

  3. Lynx1 has a role in shifting alpha4beta2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum

  4. study identified an increase in expression of Lynx1 protein that prevented plasticity in the primary visual cortex late in life; Lynx1 expression maintains stability of mature cortical networks in the presence of cholinergic innervation

  5. Results show that lynx1 colocalizes with nAChRs on CNS neurons and physically associates with nAChRs and enhances receptor desensitization, resulting in a novel type of functional modulation

Rhesus Monkey Ly6/neurotoxin 1 (LYNX1) interaction partners

  1. Lynx1 appears to act as a negative modulator of alpha7 nAChR (show CHRNA7 Antibodies)-induced events by inhibiting Src (show SRC Antibodies) activation.

Ly6/neurotoxin 1 (LYNX1) Antigen Profile

Protein Summary

This gene encodes a member of the Ly-6/neurotoxin gene family, a group of lymphocyte antigens that attach to the cell surface by a glycosylphosphatidylinositol anchor and have a unique structure showing conserved 8-10 cysteine residues with a characteristic spacing pattern. Functional analysis indicates that this protein is not a ligand or neurotransmitter but has the capacity to enhance nicotinic acetylcholine receptor function in the presence of acetylcholine. This gene may also play a role in the pathogenesis of psoriasis vulgaris. Alternatively spliced variants encoding different isoforms have been identified.

Gene names and symbols associated with LYNX1

  • Ly6/neurotoxin 1 (LYNX1) antibody
  • Ly6/neurotoxin 1 (Lynx1) antibody
  • RIKEN cDNA 2300005B03 gene (2300005B03Rik) antibody
  • AI838844 antibody
  • SLURP-2 antibody
  • Slurp2 antibody

Protein level used designations for LYNX1

Ly-6 neurotoxin-like protein 1 , SLURP-2 , ly-6/neurotoxin-like protein 1 , secreted Ly-6/uPAR domain-containing protein 2 , secreted Ly-6/uPAR-related protein 2 , secreted Ly6/uPAR related protein 2 , GC26 , secreted Ly6/uPAR related protein-2

66004 Homo sapiens
23936 Mus musculus
300018 Rattus norvegicus
516158 Bos taurus
574359 Macaca mulatta
464434 Pan troglodytes
69462 Mus musculus
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