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Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Additionally we are shipping Lymphocyte Antigen 75 Proteins (4) and Lymphocyte Antigen 75 Kits (3) and many more products for this protein.
Showing 10 out of 225 products:
Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS, IHC (fro) - ABIN111868
Breel, Mebius, Kraal: Dendritic cells of the mouse recognized by two monoclonal antibodies. in European journal of immunology 1988
Show all 7 references for ABIN111868
Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS, IF - ABIN2657026
Shrimpton, Butler, Morel, Eren, Hue, Ritter: CD205 (DEC-205): a recognition receptor for apoptotic and necrotic self. in Molecular immunology 2009
Show all 7 references for ABIN2657026
Mouse (Murine) Monoclonal LY75 Primary Antibody for ICFC - ABIN2660825
Small, Kraal: In vitro evidence for participation of DEC-205 expressed by thymic cortical epithelial cells in clearance of apoptotic thymocytes. in International immunology 2003
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Mouse (Murine) Monoclonal LY75 Primary Antibody for BR, FACS - ABIN2657157
Witmer-Pack, Swiggard, Mirza, Inaba, Steinman: Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. II. Expression in situ in lymphoid and nonlymphoid tissues. in Cellular immunology 1995
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Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS, IHC (fro) - ABIN111870
Inaba, Swiggard, Inaba, Meltzer, Mirza, Sasagawa, Nussenzweig, Steinman: Tissue distribution of the DEC-205 protein that is detected by the monoclonal antibody NLDC-145. I. Expression on dendritic cells and other subsets of mouse leukocytes. in Cellular immunology 1995
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Human Monoclonal LY75 Primary Antibody for IHC (fro), FACS - ABIN781804
Gurer, Strowig, Brilot, Pack, Trumpfheller, Arrey, Park, Steinman, Münz: Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. in Blood 2008
Show all 4 references for ABIN781804
Mouse (Murine) Monoclonal LY75 Primary Antibody for FACS, IHC (fro) - ABIN111869
Kraal, Breel, Janse, Bruin: Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody. in The Journal of experimental medicine 1986
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Human Monoclonal LY75 Primary Antibody for FACS, IHC (fro) - ABIN119792
Guo, Gong, Maric, Misulovin, Pack, Mahnke, Nussenzweig, Steinman: A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells. in Human immunology 2000
DNA vaccines encoding DEC205-targeted antigens induce peripheral tolerance rather than immunity
The DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8 (show CD8A Antibodies) T cells independently of PD-1 (show PDCD1 Antibodies) and PD-L1 (show CD274 Antibodies).
Through analysis of both polyclonal and monoclonal transgenic TCR T-cell development in the context of CD205 deficiency, we demonstrate that CD205 does not play an overt role in T cell development or selection.
Introduction of a labile dipeptide linker at the N terminus of a T-cell epitope improves proteasome-dependent class I MHC-restricted peptide cross-presentation when delivered by alphaDEC205 in vitro and in vivo.
Data indicate that the interaction between the PE-Cy5.5 conjugates and the cells expressing mDEC205 appears distinctive, since none of the PE-Cy5.5 conjugates bind to the cells that express human DEC205 on surface.
CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo
Langerin (show CD207 Antibodies)-positive dendritic cells appear to be the predominant, though not exclusive, population responsible for in vivo transport of anti-DEC-205 antibodies from the skin to the draining lymph nodes in steady state and inflammation.
For production of cytotoxic T cells, DEC-205 and Clec9A (show CLEC9A Antibodies), but not Clec12A (show CLEC12A Antibodies), are effective targets for antibody-mediated delivery of antigens for vaccination, although only in the presence of adjuvants.
Comparable T helper 1 (Th1 (show HAND1 Antibodies)) and CD8 (show CD8A Antibodies) T-cell immunity by targeting HIV gag p24 to CD8 (show CD8A Antibodies) dendritic cells within antibodies to Langerin (show CD207 Antibodies), DEC205, and Clec9A (show CLEC9A Antibodies).
show that Flt3L (show FLT3LG Antibodies) DC efficiently crosspresent HIV gag via the DEC-205 receptor, about 100 times more effective than non-targeted gag.
results suggest that DEC205 is an immune receptor that recognizes apoptotic and necrotic cells specifically through a pH-dependent mechanism
Variants in LY75 were associated with a Crohn's disease phenotype involving erythema nodosum.
DEC-205 is a cell surface receptor for CpG olligonucleotides.
The most significantly associated SNPs to type 2 diabetes mellitus in this study are expression SNPs to the lymphocyte antigen 75 gene, the ubiquitin-specific peptidase 36 (show USP36 Antibodies) gene, and the phosphatidylinositol transfer protein (show PITPNA Antibodies), cytoplasmic 1 gene.
Upregulation of LY75 is associated with ovarian tumor.
observed that TLR-mediated signaling increases DEC-205 expression levels without affecting receptor internalization
Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor (show CLEC4D Antibodies) DCL-1 (show CD302 Antibodies)
DCs and DEC-205 can cross-present several different peptides from a single protein. Data supports testing of alphaDEC-205 fusion mAb as a protein-based vaccine.
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
lymphocyte antigen 75
, DEC-205/CD205 protein
, CD205 protein
, DEC-205 protein
, Lymphocyte antigen 75
, lymphocyte antigen 75-like
, C-type lectin domain family 13 member B