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Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. Additionally we are shipping LCP1 Kits (8) and LCP1 Proteins (6) and many more products for this protein.
Showing 10 out of 82 products:
Chicken Polyclonal LCP1 Primary Antibody for WB - ABIN2785830
Klemke, Rafael, Wabnitz, Weschenfelder, Konstandin, Garbi, Autschbach, Hartschuh, Samstag: Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells. in International journal of cancer. Journal international du cancer 2007
Cytomegalovirus (CMV) Polyclonal LCP1 Primary Antibody for IHC, ELISA - ABIN1586192
Flinsenberg, Compeer, Koning, Klein, Amelung, van Baarle, Boelens, Boes: Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells. in Blood 2012
L-plastin modulates both T- and B-cell function during the germinal center reaction and the production of T-cell-dependent antibody responses.
L-plastin may participate in signaling that enables lymphocyte transmigration
LPL-dependent actin bundling facilitates the formation of lamellipodia and normal immunological synapses and thereby enables T cell activation.
Regulation of sealing ring formation by L-plastin and cortactin (show CTTN Antibodies) in osteoclasts.
We thus identify L-plastin as a molecule critical for CCR7 (show CCR7 Antibodies)-mediated t-cell motility but dispensable for early CCR7 (show CCR7 Antibodies) signaling.
Enhanced nitroxidative stress may results in LPL S-glutathionylation leading to impaired chemotaxis, polarization, and bactericidal activity of human neutrophils.
association of SNPs in LCP1 and CTIF (show KIAA0427 Antibodies) with hearing
An NKX3.1 (show NKX3-1 Antibodies) binding site polymorphism in the l-plastin promoter leads to differential gene expression in human prostate cancer
The proteins (HSP90b (show HSP90AB1 Antibodies), TSM1 and L-plastin) in the current study may hold potential in differentiating between melanoma and benign nevi in diagnostically challenging cases.
Data suggest that several single-nucleotide polymorphisms (SNPs) of the plastin genes PLS3 (show PLS3 Antibodies) and LCP1 could serve as gender- and/or stage-specific molecular predictors of tumor recurrence in stage II/III colorectal cancer as well as therapeutic targets.
L-plastin plays an important role in the clustering of NKG2D (show KLRK1 Antibodies) into lipid rafts, and it participates in NKG2D (show KLRK1 Antibodies)-mediated inhibition of NK cell chemotaxis.
expression of L-plastin promotes tumor metastasis and, importantly, that this effect depends on an additionally required phosphorylation of L-plastin
L-plastin is indispensable for podosome formation and function in macrophages.
LCP1 is functionally relevant to CXCL12 (show CXCL12 Antibodies) induced B-cell migration.
High serum LCP1 is associated with kidney cancer.
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
, leucocyte-specific plastin 1
, 65 kDa macrophage protein
, L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65)
, plastin 2, L
, L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)
, Lymphocyte cytosolic protein-1 (plasmin)
, bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin))
, plastin 2
, epidermal Langerhans cell protein LCP1