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anti-Lymphocyte Transmembrane Adaptor 1 (LAX1) Antibodies

Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells (By similarity). Additionally we are shipping LAX1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAX1 54900 Q8IWV1
LAX1 240754 Q8BHB3
LAX1 498232 Q5FVQ5
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Top anti-LAX1 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-LAX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LAX1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-LAX1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  LAX1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB LAX1 Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LAX1 antibody detected the LAX1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB LAX1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

LAX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
, ,

, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-LAX1 Antibodies

  1. Cow (Bovine) Polyclonal LAX1 Primary Antibody for WB - ABIN2782914 : Zhu, Granillo, Wen, Yang, Dai, Wang, Zhang: Negative regulation of lymphocyte activation by the adaptor protein LAX. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

More Antibodies against LAX1 Interaction Partners

Human Lymphocyte Transmembrane Adaptor 1 (LAX1) interaction partners

  1. TRIM (show TRAT1 Antibodies) required LAX for binding to Rab8 (show RAB8A Antibodies) in a complex, a novel CTLA-4 (show CTLA4 Antibodies)/TRIM (show TRAT1 Antibodies)/LAX/Rab8 (show RAB8A Antibodies) effector complex in the transport of CTLA-4 (show CTLA4 Antibodies) to the surfaces of T cells

  2. We identified the transmembrane domain of LAX as a first motif targeting transmembrane protein constructs to detergent-resistant heavy rafts, a novel type of membrane microdomains containing a number of physiologically important proteins.

  3. Overexpression of LAX in Jurkat cells specifically inhibits T cell receptor-mediated p38 MAPK (show MAPK14 Antibodies) activation and NFAT (show NFATC1 Antibodies)/AP-1 (show FOSB Antibodies) transcriptional activation.

  4. inhibition of signaling events involved in T cell activation by LAX occurs through mechanisms both dependent on and independent of its tyrosine phosphorylation.

Mouse (Murine) Lymphocyte Transmembrane Adaptor 1 (LAX1) interaction partners

  1. SIT and LAX are important negative regulators of immune responses that functionally cooperate.

  2. Upon T or B cell activation (show BLNK Antibodies), the LAX protein is up-regulated dramatically. This in vivo study of LAX-deficient mice demonstrates that LAX functions as a negative regulator in lymphocyte signaling.

  3. LAX negatively regulates mast cell function

LAX1 Antigen Profile

Protein Summary

Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells (By similarity).

Gene names and symbols associated with LAX1

  • lymphocyte transmembrane adaptor 1 (LAX1) antibody
  • lymphocyte transmembrane adaptor 1 (LOC100359066) antibody
  • lymphocyte transmembrane adaptor 1 (Lax1) antibody
  • A530029E09 antibody
  • E430019B13Rik antibody
  • LAX antibody

Protein level used designations for LAX1

lymphocyte transmembrane adaptor 1 , lymphocyte transmembrane adapter 1-like , LAT-like membrane associated protein , linker for activation of x cells , lymphocyte transmembrane adapter 1 , membrane-associated adapter protein LAX , membrane associated adaptor protein LAX , linker for activation of X cells

GENE ID SPECIES
702011 Macaca mulatta
741370 Pan troglodytes
100359066 Oryctolagus cuniculus
100397361 Callithrix jacchus
100437319 Pongo abelii
100589202 Nomascus leucogenys
54900 Homo sapiens
540424 Bos taurus
240754 Mus musculus
498232 Rattus norvegicus
Selected quality suppliers for anti-LAX1 (LAX1) Antibodies
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