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anti-Lymphocyte-Activation Gene 3 (LAG3) Antibodies

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. Additionally we are shipping Lymphocyte-Activation Gene 3 Proteins (26) and Lymphocyte-Activation Gene 3 Kits (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LAG3 16768 Q61790
LAG3 3902 P18627
LAG3 297596 Q5BK54
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Top anti-Lymphocyte-Activation Gene 3 Antibodies at antibodies-online.com

Showing 10 out of 212 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat PE FACS Staining of CD223 transfected cells with RAT ANTI MOUSE CD223:RPE(ABIN120325) 100 Tests Log in to see 6 to 8 Days
$253.00
Details
Mouse Rat Un-conjugated FACS Staining of CD223 transfected cells with RAT ANTI MOUSE CD223 (ABIN120324) 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated FACS, IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-LAG-3/CD223 Polyclonal Antibody, Unconjugated (ABIN748508) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (fro), IP, WB Flow Cytometry: LAG-3 Antibody (17B4) [NBP1-97657] - Analysis using the FITC conjugate of NBP1-97657. Staining of LAG-3 on CD4+ and CD8+ subpopulations of tumour infiltrating lymphocytes (TILs) detected with LAG-3 (human), mAb (17B4) (FITC). Method: TILs from a dissociated renal cell carcinoma sample, stain Flow Cytometry: LAG-3 Antibody (17B4) [NBP1-97657] - Analysis using the FITC conjugate of NBP1-97657. Tumor infiltrating lymphocytes (TILs) express LAG-3 (detected using LAG-3 (human), mAb (17B4). Method: Freshly dissociated single cell suspensions of renal cell carcinoma TILs are incubated with LAG-3 (huma 0.05 mg Log in to see 6 to 9 Days
$447.56
Details
Human Mouse Alexa Fluor 700 FACS Detection of LAG-3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 1 ug/mL PHA for 5 days were stained with Mouse Anti-Human LAG-3 Alexa Fluor 700-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$465.94
Details
Human Mouse FITC FACS Flow Cytometry: LAG-3 Antibody (17B4) [FITC] [NBP1-97665] - Specific inhibition of 17B4 staining.Method: LAG-3 (human), mAb (17B4) (FITC) (10ug/ml) (is preincubated with a specific peptide epitope (208b) or a control tetanus toxoid (TT) peptide at different molarities prior to staining of TILs. Stained cells are then analyzed by FC. Flow Cytometry: LAG-3 Antibody (17B4) [FITC] [NBP1-97665] - LAG-3 staining in resting and PHA activated lymphocytes. Image from verified customer review. 0.05 mg Log in to see 5 to 7 Days
$500.06
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-LAG3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart WB Suggested Anti-LAG3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat PE FACS Detection of LAG-3 in Human PBMCs by Flow Cytometry. CD3+ PHA-treated peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$446.25
Details
Human Goat Biotin FACS, WB Detection of LAG-3 in CD3+ Human PBMCs by Flow Cytometry. CD3+ Human peripheral blood mononuclear cells (PBMCs) treated with 5 ug/mL PHA for 5 days were stained with Mouse Anti-Human CD3 epsilon PE-conjugated Monoclonal Antibody. 50 μg Log in to see 6 to 7 Days
$505.31
Details
Mouse Rat Un-conjugated Func, FACS   0.5 mg Log in to see 6 to 8 Days
$632.50
Details

LAG3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Lymphocyte-Activation Gene 3 Antibodies

  1. Human Monoclonal LAG3 Primary Antibody for Func, ICC - ABIN1169105 : Hannier, Tournier, Bismuth, Triebel: CD3/TCR complex-associated lymphocyte activation gene-3 molecules inhibit CD3/TCR signaling. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 8 references for ABIN1169105

  2. Human Polyclonal LAG3 Primary Antibody for FACS - ABIN4896615 : Melve, Ersvaer, Akkök, Ahmed, Kristoffersen, Hervig, Bruserud: Immunomodulation Induced by Stem Cell Mobilization and Harvesting in Healthy Donors: Increased Systemic Osteopontin Levels after Treatment with Granulocyte Colony-Stimulating Factor. in International journal of molecular sciences 2016 (PubMed)
    Show all 5 references for ABIN4896615

  3. Mouse (Murine) Monoclonal LAG3 Primary Antibody for Func, FACS - ABIN120322 : Workman, Rice, Dugger, Kurschner, Vignali: Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). in European journal of immunology 2002 (PubMed)
    Show all 2 references for ABIN120322

  4. Mouse (Murine) Monoclonal LAG3 Primary Antibody for FACS - ABIN120325 : Workman, Vignali: Negative regulation of T cell homeostasis by lymphocyte activation gene-3 (CD223). in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)
    Show all 2 references for ABIN120325

  5. Human Polyclonal LAG3 Primary Antibody for FACS, IF (cc) - ABIN748508 : Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes. in Cancer immunology, immunotherapy : CII 2013 (PubMed)

  6. Human Polyclonal LAG3 Primary Antibody for FACS, WB - ABIN4899755 : Illingworth, Butler, Roetynck, Mwacharo, Pierce, Bejon, Crompton, Marsh, Ndungu: Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion. in Journal of immunology (Baltimore, Md. : 1950) 2013 (PubMed)

  7. Human Monoclonal LAG3 Primary Antibody for FACS - ABIN4896610 : Kong, Zhang, Claxton, Ehmann, Rybka, Zhu, Zeng, Schell, Zheng: PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation. in Blood cancer journal 2015 (PubMed)

More Antibodies against Lymphocyte-Activation Gene 3 Interaction Partners

Cow (Bovine) Lymphocyte-Activation Gene 3 (LAG3) interaction partners

Rhesus Monkey Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. We show that the expression of LAG3 is highly induced in the lungs and particularly in the granulomatous lesions of macaques experimentally infected with mycobacterium tuberculosis.

Mouse (Murine) Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. Study suggests that expression of the inhibitory receptors PD-1 (show PDCD1 Antibodies) and LAG-3 on CD4 (show CD4 Antibodies)(+) T cells and their reduced IL-2 (show IL2 Antibodies) production are common characteristic features of Plasmodium infection.

  2. An IL-27 (show IL27 Antibodies)/Lag3 axis enhances Foxp3 (show FOXP3 Antibodies)+ regulatory T cell-suppressive function and therapeutic efficacy.

  3. LAG3 and PD1 (show PDCD1 Antibodies) co-inhibitory molecules have roles in collaborating to limit CD8 (show CD8A Antibodies)+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

  4. Poxvirus-Based Active Immunotherapy with PD-1 (show PDCD1 Antibodies) and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.

  5. Lymphatic endothelial cells (LECs) serve as an antigen reservoir for CD4 (show CD4 Antibodies) T-cell tolerance, and MHC-II molecules on LECs are used to induce CD8 (show CD8A Antibodies) T-cell tolerance via LAG-3.

  6. LAG-3 expression on Tconv cells makes them more susceptible to Treg based suppression, and also regulates the development of a TH1 (show HAND1 Antibodies) T-cell response.

  7. LAG-3 exerts an important regulatory effect on autoimmunity.

  8. Lag-3 is an important regulatory molecule involved in alloreactive T cell proliferation and activation after bone marrow transplantation.

  9. these results define a strong synergy between the PD-1 (show PDCD1 Antibodies) and LAG-3 inhibitory pathways in tolerance to both self and tumor antigens.

  10. We conclude that LAG-3 is necessary for regulating CD4 (show CD4 Antibodies)(+) and CD8 (show CD8A Antibodies)(+) T cell function during autoimmune diabetes

Human Lymphocyte-Activation Gene 3 (LAG3) interaction partners

  1. An IL-27 (show IL27 Antibodies)/Lag3 axis enhances Foxp3 (show FOXP3 Antibodies)+ regulatory T cell-suppressive function and therapeutic efficacy.

  2. LAG-3 is highly expressed in peripheral blood CD8 (show CD8A Antibodies)+ T cells in chronic HBV-infected patients.

  3. Data indicate that in recurrent spontaneous abortion patients, the expression levels of CD49b (show ITGA2 Antibodies) and LAG-3 (CD223) on CD14 (show NDUFA2 Antibodies)(+) mononuclear cells and the plasma level of transforming growth factor beta (TGF-beta) decreased obviously compared with normal females.

  4. iNKT cytokine production is profoundly altered by both HIV infection and treatment, and LAG-3, but not PD-1 (show PDCD1 Antibodies), expression is associated with a reduction in iNKT IFNgamma production.

  5. NFKB1 (show NFKB1 Antibodies), CD27 (show CD27 Antibodies), LAG3 and IKZF3 (show IKZF3 Antibodies) are new susceptibility genes for psoriasis.

  6. The elevated expression of LAG-3 at the genital tract suggests it may regulate T-cell activation, and identify cells susceptible to HIV infection. The enrichment of LAG-3 on double negative T cells suggests LAG-3 may contribute to the immunoregulatory activity of these cells.

  7. the LAG-3/MHC class II (show HLA-DPA1 Antibodies) pathway may synergize with PD-1 (show PDCD1 Antibodies)/PD ligand to enhance T cell-mediated immune responses.

  8. LAG-3 trafficking from lysosomal compartments to the cell surface is dependent on the cytoplasmic domain through protein kinase C (show PKC Antibodies) signaling in activated T cells.

  9. These results suggest that LAG-3-mediated activation of plasmacytoid dendritic cells takes place in vivo at tumor sites, and it is in part responsible for directing an immune-suppressive environment.

  10. Expression of LAG-3 is coincident with the impaired effector function of HBV-specific CD8 (show CD8A Antibodies)(+) T cell in HCC (show FAM126A Antibodies) patients.

Lymphocyte-Activation Gene 3 (LAG3) Antigen Profile

Protein Summary

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

Gene names and symbols associated with LAG3

  • lymphocyte-activation gene 3 (LAG3) antibody
  • lymphocyte-activation gene 3 (Lag3) antibody
  • CD223 antibody
  • LAG-3 antibody
  • Ly66 antibody

Protein level used designations for LAG3

lymphocyte-activation gene 3 , lymphocyte-activation protein 3 , lymphocyte-activation protein 3-like , lymphocyte activation gene 3 protein-like , lymphocyte activation gene 3 protein , LAG-3 , lymphocyte activation gene 3

GENE ID SPECIES
418287 Gallus gallus
451794 Pan troglodytes
515155 Bos taurus
713737 Macaca mulatta
100059998 Equus caballus
100415501 Callithrix jacchus
100452007 Pongo abelii
16768 Mus musculus
3902 Homo sapiens
297596 Rattus norvegicus
100125962 Sus scrofa
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