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The protein encode dby LRMP is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. Additionally we are shipping LRMP Proteins (5) and many more products for this protein.
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Lrmp's maternally inherited products are essential for nucleus-centrosome attachment and pronuclear congression during fertilization. Subcellular localization of lrmp products also suggests spatiotemporal regulation of their function in the early embryo.
The Lrmp protein is associated with type III IP3 receptor (IP3R3 (show ITPR3 Antibodies)) via its coiled-coil domain in the heterologous expression system.
Lrmp is a condidate for the type I diabetes susceptility locus Idd6.
Lrmp is part of the complex multigenic Pas1 locus, with a functional role for its intragenic polymorphisms and AA changes in lung tumor susceptibility.It may be a tumor suppressor.
We hypothesize that the observed decrease in expression of the Lrmp gene in NOD mice may constitute a T1D susceptibility factor in the Idd6 region.
The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum.
lymphoid-restricted membrane protein
, futile cycle
, Lymphoid-restricted membrane protein-like
, protein Jaw1