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anti-Lysine (K)-Specific Demethylase 4B (KDM4B) Antibodies

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KDM4B 23030 O94953
KDM4B 193796 Q91VY5
KDM4B    
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Top anti-KDM4B Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-JMJD2B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human kidney WB Suggested Anti-JMJD2B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-JMJD2B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB JMJD2B Antibody (N-term) (ABIN655890) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the JMJD2B antibody detected the JMJD2B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of JMJD2B Antibody (N-term) (ABIN653341) in K562 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Phospho-JMJD2B-pT305 (ABIN653576) in MDA-MB435 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. Western blot analysis of Phospho-JMJD2B-pT305 (ABIN653576) in NIH-3T3 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of JMJD2B Antibody (N-term) in A375 cell line lysates (35ug/lane). This demonstrates the JMJD2B antibody detected the JMJD2B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Phospho-JMJD2B-pT305 in MDA-MB435 cell line lysates (35ug/lane). JMJD2B (arrow) was detected using the purified Pab. Western blot analysis of Phospho-JMJD2B-pT305 in NIH-3T3 cell line lysates (35ug/lane). JMJD2B (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of K562 cells using JMJD2B Antibody (N-term) Cat.-No AP52269PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$401.50
Details

KDM4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-KDM4B Antibodies

  1. Human Polyclonal KDM4B Primary Antibody for EIA, FACS - ABIN952973 : Beyer, Kristensen, Jensen, Johansen, Staller: The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. in The Journal of biological chemistry 2008 (PubMed)
    Show all 5 references for ABIN952973

  2. Human Polyclonal KDM4B Primary Antibody for EIA, WB - ABIN952974 : Pollard, Loenarz, Mole, McDonough, Gleadle, Schofield, Ratcliffe: Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. in The Biochemical journal 2008 (PubMed)
    Show all 3 references for ABIN952974

  3. Human Polyclonal KDM4B Primary Antibody for EIA, WB - ABIN952972 : Yang, Jubb, Pike, Buffa, Turley, Baban, Leek, Gatter, Ragoussis, Harris: The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. in Cancer research 2010 (PubMed)
    Show all 3 references for ABIN952972

  4. Human Polyclonal KDM4B Primary Antibody for FACS, IHC (p) - ABIN653341 : Gray, Iglesias, Lizcano, Villanueva, Camelo, Jingu, Teh, Koibuchi, Chin, Kokkotou, Dangond: Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN653341

  5. Human Polyclonal KDM4B Primary Antibody for EIA, WB - ABIN500082 : Katoh, Katoh: Identification and characterization of JMJD2 family genes in silico. in International journal of oncology 2004 (PubMed)

  6. Dog (Canine) Polyclonal KDM4B Primary Antibody for WB - ABIN2787663 : Katoh, Katoh: Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells. in International journal of molecular medicine 2007 (PubMed)

More Antibodies against KDM4B Interaction Partners

Human Lysine (K)-Specific Demethylase 4B (KDM4B) interaction partners

  1. High KDM4B expression is associated with endometrial cancer progression.

  2. JMJD2B and JMJD2C (show KDM4C Antibodies) play an important role in the pathology of osteosarcoma via the up-regulation of FGF2 (show FGF2 Antibodies).

  3. results reveal that JMJD2B is dramatically upregulated in hepatocellular carcinoma, making it a potential diagnostic marker for the further development of HCC (show FAM126A Antibodies) treatment therapies

  4. Functional studies demonstrated that KDM4B regulates the Myc (show MYC Antibodies) pathway. N-Myc (show MYCN Antibodies) was found to physically interact with and recruit KDM4B. KDM4B was found to regulate neuroblastoma (show ARHGEF16 Antibodies) cell proliferation and differentiation in vitro and xenograft growth in vivo.

  5. Data indicate that miR (show MLXIP Antibodies)-491-5p plays a tumor suppressor role in the development and progression of breast cancer via direct targeting the 3'UTR (show UTS2R Antibodies) of JMJD2B mRNA.

  6. Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.

  7. KDM4B was upregulated in colon and rectal adenocarcinomas and required for efficient growth and clonogenic activity of human HT-29 colon cancer cells.

  8. A novel function of JMJD2B in promoting epithelial-mesenchymal transition and gastric cancer invasion and metastasis.

  9. Results suggest that by regulating JMJD2b and SUV39H1 (show SUV39H1 Antibodies) expression, p53 (show TP53 Antibodies) not only controls transcription but also promotes HC relaxation to accelerate a rate-limiting step in the repair of complex genomes.

  10. Jumonji domain-containing protein 2B has an essential role in cancer cell survival and tumor growth via DNA damage response mediation, which STAT3 (show STAT3 Antibodies) partially regulates.

Mouse (Murine) Lysine (K)-Specific Demethylase 4B (KDM4B) interaction partners

  1. KDM4B histone demethylase (show MBD2 Antibodies) regulates expression of myogenic regulators such as MyoD (show MYOD1 Antibodies) and thereby controls myogenic differentiation of C2C12 myoblast cells.

  2. Jmjd2b unique, Jmjd2c (show KDM4C Antibodies) unique, and Jmjd2b-Jmjd2c (show KDM4C Antibodies) common target sites belong to functionally separable Core, Polycomb (show CBX2 Antibodies) repressive complex (PRC (show PPRC1 Antibodies)), and Myc (show MYC Antibodies) regulatory modules, respectively.

  3. This study establishes novel Jmjd2b targets that potentiate a biological rationale involving Jmjd2b in NSC inflammation.

  4. The promoter of Kdm4b is bound and activated by C/EBPbeta (show CEBPB Antibodies)

  5. Induction of Jmjd2b in the embryonic stem cells decreased total levels of histone-3 lysine-9 trimethylation (H3K9me3) by 63%.

  6. Data indicate that Myst4 (show KAT6B Antibodies), Jmjd2b, Aof1 (show KDM1B Antibodies) genes are regulated by H3K9me under hyperinsulinemia/hyperglycemia.

  7. A subgroup of murine Jmjd2 (show KDM4A Antibodies) proteins antagonize H3K9me3 at pericentric heterochromatin.

KDM4B Antigen Profile

Protein Summary

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Gene names and symbols associated with KDM4B

  • lysine (K)-specific demethylase 4B (KDM4B) antibody
  • lysine (K)-specific demethylase 4B (kdm4b) antibody
  • lysine (K)-specific demethylase 4B (Kdm4b) antibody
  • 4732474L06Rik antibody
  • Jmjd2b antibody
  • KDM4B antibody
  • mKIAA0876 antibody
  • si:ch211-124a3.4 antibody
  • TDRD14B antibody

Protein level used designations for KDM4B

lysine (K)-specific demethylase 4B , jumonji domain containing 2B , lysine-specific demethylase 4B , lysine-specific demethylase 4B-like , jmjC domain-containing histone demethylation protein 3B , jumonji domain-containing protein 2B , tudor domain containing 14B

GENE ID SPECIES
455614 Pan troglodytes
556504 Danio rerio
100023921 Monodelphis domestica
100511181 Sus scrofa
100541123 Meleagris gallopavo
100563051 Anolis carolinensis
100582140 Nomascus leucogenys
23030 Homo sapiens
193796 Mus musculus
476741 Canis lupus familiaris
508141 Bos taurus
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