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anti-Lysine (K)-Specific Demethylase 4C (KDM4C) Antibodies

KDM4C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. Additionally we are shipping KDM4C Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KDM4C 23081 Q9H3R0
KDM4C 76804 Q8VCD7
KDM4C 298144  
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Top anti-KDM4C Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: JMJD2CAntibody Dilution: 1.0ug/mlSample Tissue: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, WB JMJD2C Antibody (C-term) (ABIN655391) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of K562 cells usinb JMJD2C Antibody (C-term) Cat.-No AP52272PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of JMJD2C Antibody (C-term) in K562 cell line lysates (35ug/lane). This demonstrates the JMJD2C antibody detected the JMJD2C protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 2 to 3 Days
$220.50
Details
Human Mouse Un-conjugated FACS, IF, IHC Immunohistochemical staining of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2453191, Dilution 1:50) Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2453191, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2452519, Dilution 1:50) Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2452519, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, IHC, WB Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2452629, Dilution 1:50) Immunohistochemical staining of paraffin-embedded colon tissue using anti-KDM4C mouse monoclonal antibody. (ABIN2452629, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details

KDM4C Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


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Rat (Rattus)


Top referenced anti-KDM4C Antibodies

  1. Human Polyclonal KDM4C Primary Antibody for EIA, FACS - ABIN952976 : Suikki, Kujala, Tammela, van Weerden, Vessella, Visakorpi: Genetic alterations and changes in expression of histone demethylases in prostate cancer. in The Prostate 2010 (PubMed)
    Show all 2 references for ABIN952976

  2. Human Polyclonal KDM4C Primary Antibody for EIA, WB - ABIN493083 : Yi, Hao, Yang, Wang, Xing, Xu: cDNA cloning, bioinformatic and tissue-specific expression analysis of porcine JARID1C gene. in Journal of genetics and genomics = Yi chuan xue bao 2007 (PubMed)
    Show all 2 references for ABIN493083

  3. Human Polyclonal KDM4C Primary Antibody for FACS, WB - ABIN655391 : Liu, Bollig-Fischer, Kreike, van de Vijver, Abrams, Ethier, Yang: Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer. in Oncogene 2009 (PubMed)
    Show all 2 references for ABIN655391

  4. Human Polyclonal KDM4C Primary Antibody for WB - ABIN2777688 : Lu, Ward, Kapoor, Rohle, Turcan, Abdel-Wahab, Edwards, Khanin, Figueroa, Melnick, Wellen, ORourke, Berger, Chan, Levine, Mellinghoff, Thompson: IDH mutation impairs histone demethylation and results in a block to cell differentiation. in Nature 2012 (PubMed)

More Antibodies against KDM4C Interaction Partners

Cow (Bovine) Lysine (K)-Specific Demethylase 4C (KDM4C) interaction partners

  1. Histone demethylases KDM3A (show KDM3A Antibodies), KDM4A (show KDM4A Antibodies), and KDM4C were expressed before and after embryonic genome activation, whereas KDM5B (show KDM5B Antibodies) was mainly expressed during the blastocyst period.

Human Lysine (K)-Specific Demethylase 4C (KDM4C) interaction partners

  1. KDM4C recognition of H3K4me3 stimulates demethylation of H3K9me3 in cis (show CISH Antibodies) on peptide and mononucleosome substrates.

  2. Pharmacological inhibition of KDM4C/PRMT1 (show PRMT1 Antibodies) suppresses transcription and transformation ability of MLL (show MLL Antibodies) fusions

  3. JMJD2B (show KDM4B Antibodies) and JMJD2C play an important role in the pathology of osteosarcoma via the up-regulation of FGF2 (show FGF2 Antibodies).

  4. Data suggest that D396N polymorphism of JmjC domain-containing histone demethylase (show MBD2 Antibodies) JMJD2C affects the prognosis of breast cancer by altering caspase-3 (show CASP3 Antibodies) cleavage and the ability of double strand DNA break repair which may contribute to therapy resistance.

  5. GASC1 expression is higher in adenocarcinoma than squamous cell carcinoma. Smoking decreases GASC1 expression in tumor cells, indicating that tobacco smoke may influence the methylation of histone 3 lysine residues in lung cancer.

  6. KDM4C promotes transcriptional activation by removing the repressive histone mark, H3K9me3, from its target genes. Variation in its expression leads to differences in the growth of normal and some cancer cells.

  7. KDM4C maintains the sphere-forming capacity in CRCs by mediating the beta-catenin (show CTNNB1 Antibodies)-dependent transcription of JAG1 (show JAG1 Antibodies) in a feed-forward manner.

  8. analysis of the nickel-induced inhibition of truncated constructs of JMJD2A (show KDM4A Antibodies) and JMJD2C histone demethylases using X-ray absorption spectroscopy

  9. Patients with GASC1 positive tumors have better breast cancer specific survival and respond better to radiotherapy and hormonal treatment

  10. JMJD2C decreases trimethylation of histone H3 (show HIST3H3 Antibodies) at lysine 9, and enhances HIF-1 (show HIF1A Antibodies) binding to hypoxia response elements, thereby activating transcription of proteins that are required for metabolic reprogramming and for lung metastasis.

Mouse (Murine) Lysine (K)-Specific Demethylase 4C (KDM4C) interaction partners

  1. GASC1 has an oncogenic role in mouse skin carcinogenesis.

  2. These findings together demonstrate the essential role of KDM4A (show KDM4A Antibodies) and KDM4C in orchestrating mESC differentiation to endothelial cells through the activation of Flk1 (show KDR Antibodies) and VE-cadherin (show CDH5 Antibodies) promoters, respectively

  3. Pharmacological inhibition of KDM4C/PRMT1 (show PRMT1 Antibodies) suppresses transcription and transformation ability of MLL (show MLL Antibodies) fusions

  4. Jmjd2C increases MyoD (show MYOD1 Antibodies) transcriptional activity to facilitate skeletal muscle differentiation by increasing MyoD (show MYOD1 Antibodies) stability through inhibiting G9a (show EHMT2 Antibodies)-dependent MyoD (show MYOD1 Antibodies) degradation.

  5. Jmjd2b (show KDM4B Antibodies) unique, Jmjd2c unique, and Jmjd2b (show KDM4B Antibodies)-Jmjd2c common target sites belong to functionally separable Core, Polycomb (show CBX2 Antibodies) repressive complex (PRC (show PPRC1 Antibodies)), and Myc (show MYC Antibodies) regulatory modules, respectively.

  6. Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation.

  7. stage-specifically expressed during preimplantation development (show MTA2 Antibodies), with the highest activity being observed from the two-cell to the eight-cell stage

  8. Jmjd2c acts as a positive regulator for Nanog, which encodes for a key transcription factor for self-renewal in ES cells.

  9. These results indicate that Mdm2 (show MDM2 Antibodies) oncogene (show RAB1A Antibodies) is a downstream target of Jmjd2c and may play an important role in Jmjd2c-mediated oncogenesis.

KDM4C Antigen Profile

Protein Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KDM4C

  • lysine (K)-specific demethylase 4C (KDM4C) antibody
  • jumonji domain containing 2c (Jmjd2c) antibody
  • lysine (K)-specific demethylase 4C (kdm4c) antibody
  • lysine (K)-specific demethylase 4C (Kdm4c) antibody
  • 2410141F18Rik antibody
  • AA517467 antibody
  • bA146B14.1 antibody
  • Gasc1 antibody
  • JHDM3C antibody
  • Jmjd2c antibody
  • TDRD14C antibody

Protein level used designations for KDM4C

jumonji domain containing 2C , lysine (K)-specific demethylase 4C , jumonji domain containing 2c , lysine-specific demethylase 4C , lysine-specific demethylase 4C-like , GASC-1 protein , JmjC domain-containing histone demethylation protein 3C , gene amplified in squamous cell carcinoma 1 protein , jumonji domain-containing protein 2C , tudor domain containing 14C , gene amplified in squamous cell carcinoma 1 , jmjC domain-containing histone demethylation protein 3C

GENE ID SPECIES
427231 Gallus gallus
464989 Pan troglodytes
474704 Canis lupus familiaris
100060699 Equus caballus
100329036 Saccoglossus kowalevskii
535671 Bos taurus
715273 Macaca mulatta
100343440 Oryctolagus cuniculus
100391630 Callithrix jacchus
100475996 Ailuropoda melanoleuca
100551717 Anolis carolinensis
100592056 Nomascus leucogenys
23081 Homo sapiens
76804 Mus musculus
298144 Rattus norvegicus
Selected quality suppliers for anti-KDM4C (KDM4C) Antibodies
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