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Lysine (K)-Specific Demethylase 4D Proteins (KDM4D)

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Additionally we are shipping Lysine (K)-Specific Demethylase 4D Antibodies (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KDM4D 55693 Q6B0I6
KDM4D 244694 Q3U2K5
KDM4D 689582 A1A5Q5
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Top Lysine (K)-Specific Demethylase 4D Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,448.50
Details
HOST_Baculovirus Human DYKDDDDK Tag JMJD2D / KDM4D activity assay. Recombinant JMJD2D / KDM4D activity measured using a demethylation assay. MALDI-TOF was used for detection. Recombinant JMJD2D / KDM4D activity using AlphaLISA. JMJD2D / KDM4D was used in an AlphaLISA assay to determine enzyme titration. An IC50 dose response assessment of reference compounds 2,4-PDCA and N-OG is shown. This data was generated and kindly provided courtesy of ChemPartner. 20 μg Log in to see 1 to 2 Days
$460.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

KDM4D Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Lysine (K)-Specific Demethylase 4D (KDM4D) Interaction Partners

Human Lysine (K)-Specific Demethylase 4D (KDM4D) interaction partners

  1. KDM4D-RNA interaction is required for KDM4D accumulation at DNA breakage sites

  2. PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.

  3. The molecular basis for JMJD2 (show KDM4A Proteins) site specificity revealed by X-ray crystallography.

  4. Results demonstrate that JMJD2D can stimulate cell proliferation and survival, suggesting that its inhibition may be helpful in the fight against cancer

  5. identified two related histone demethylases, JMJD2A (show KDM4A Proteins) and JMJD2D

Mouse (Murine) Lysine (K)-Specific Demethylase 4D (KDM4D) interaction partners

  1. These results suggest that demethylation of H3K9 in round spermatids is dispensable for spermatogenesis but that possible defects in Kdm4d-null elongating spermatids could be rescued by functional redundancy of the KDM4B demethylase.

Lysine (K)-Specific Demethylase 4D (KDM4D) Protein Profile

Protein Summary

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).

Gene names and symbols associated with KDM4D

  • jumonji domain containing 2D (JMJD2D)
  • lysine (K)-specific demethylase 4D (KDM4D)
  • lysine (K)-specific demethylase 4D (Kdm4d)
  • 4932416A15 protein
  • Jmjd2d protein
  • KDM4D protein

Protein level used designations for KDM4D

jumonji domain containing 2D , lysine (K)-specific demethylase 4D , lysine-specific demethylase 4D-like , lysine-specific demethylase 4D , jmjC domain-containing histone demethylation protein 3D , jumonji domain-containing protein 2D

GENE ID SPECIES
524768 Bos taurus
451494 Pan troglodytes
466754 Pan troglodytes
466755 Pan troglodytes
617971 Bos taurus
100067461 Equus caballus
698455 Macaca mulatta
100408074 Callithrix jacchus
100449542 Pongo abelii
100475904 Ailuropoda melanoleuca
100514356 Sus scrofa
100597675 Nomascus leucogenys
55693 Homo sapiens
244694 Mus musculus
689582 Rattus norvegicus
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