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anti-Lysine (K)-Specific Demethylase 5B (KDM5B) Antibodies

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Additionally we are shipping KDM5B Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KDM5B 10765 Q9UGL1
KDM5B 75605 Q80Y84
KDM5B 304809  
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Top anti-KDM5B Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB JARID1B Antibody (N-term) (ABIN658397) western blot analysis in mouse testis tissue lysates (35 µg/lane). This demonstrates the JARID1B antibody detected the JARID1B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB JARID1B monoclonal antibody (M02), clone 1G10. Western Blot analysis of JARID1B expression in Hela NE on formalin-fixed paraffin-embedded human colon (antibody concentration 1 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB KDM5B monoclonal antibody (M02A), clone 1G10. Western Blot analysis of KDM5B expression in Hela NE . (170kD,OMIM,http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605393) KDM5B monoclonal antibody (M02A), clone 1G10. Western Blot analysis of KDM5B expression in NIH/3T3 200 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to KDM5B on formalin-fixed paraffin-embedded human colon. [antibody concentration 1 ug/ml] KDM5B monoclonal antibody (M02), clone 1G10. Western Blot analysis of KDM5B expression in Hela NE . (170kD,OMIM,http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605393) 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.9 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 2 to 3 Days
$220.50
Details
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 3 to 4 Days
$601.76
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-KDM5B/PLU1/Jarid1B Polyclonal Antibody, Unconjugated (ABIN762986) at 1:200 followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in Microplate Reader by 450nm 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Mouse Un-conjugated IF, ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details

KDM5B Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-KDM5B Antibodies

  1. Human Monoclonal KDM5B Primary Antibody for WB - ABIN395143 : Roesch, Fukunaga-Kalabis, Schmidt, Zabierowski, Brafford, Vultur, Basu, Gimotty, Vogt, Herlyn: A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. in Cell 2010 (PubMed)
    Show all 7 references for ABIN395143

  2. Mouse (Murine) Polyclonal KDM5B Primary Antibody for WB - ABIN658397 : Kim, Shin, Subramaniam, Bruinsma, Kim, Hawse, Spelsberg, Janknecht: Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN658397

  3. Human Monoclonal KDM5B Primary Antibody for IF, IHC (p) - ABIN1327126 : Xiang, Zhu, Han, Ye, Xu, Peng, Ma, Yu, Lin, Chen, Chen: JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 3 references for ABIN1327126

  4. Human Monoclonal KDM5B Primary Antibody for ELISA, WB - ABIN524186 : Hayami, Yoshimatsu, Veerakumarasivam, Unoki, Iwai, Tsunoda, Field, Kelly, Neal, Yamaue, Ponder, Nakamura, Hamamoto: Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway. in Molecular cancer 2010 (PubMed)

More Antibodies against KDM5B Interaction Partners

Human Lysine (K)-Specific Demethylase 5B (KDM5B) interaction partners

  1. KDM5B, a histone demethylase (show MBD2 Antibodies) known to be involved in breast cancer tumorigenesis, as a target of miR (show MLXIP Antibodies)-137.

  2. Data show that KDM5B is frequently up-regulated in hepatocellular carcinoma tissues and cell lines and correlated with poor prognosis. Its depletion leads to highly impaired clonogenesis and cell cycle arrest through up-regulation of p15 (show CDKN2B Antibodies) and p27 (show PAK2 Antibodies).

  3. the presented data suggest a mechanism through which Ikaros (show IKZF1 Antibodies) and HDAC1 (show HDAC1 Antibodies) regulate the epigenetic signature in leukemia: via regulation of JARID1B transcription.

  4. Characterization of a Linked Jumonji (show JARID2 Antibodies) Domain of the KDM5/JARID1 Family of Histone H3 (show HIST3H3 Antibodies) Lysine 4 Demethylases.

  5. The data demonstrated that protein expression of p16 (show CDKN2A Antibodies) and JARID1B/KDM5B is negatively correlated in invasive ductal carcinoma of the breast.

  6. provided evidence that JARID1B via modulation of stemness-related signaling is a putative novel therapeutic target for treating malignant NB

  7. Our results, for the first time, portray a pivotal role of JARID1B in stimulating metastatic behaviors of hepatocellular carcinoma cells

  8. Our results collectively suggested that JARID1B expressed in lung cancer played a role in lung cancer cells proliferation and invasion, which may be partly associated with the p53 (show TP53 Antibodies) expression

  9. PLU-1/JARID1B represents a candidate proliferation biomarker for HNSCC diagnosis and treatment.

  10. This study revealed hyper JARID1B expression and hypo histone H3 (show HIST3H3 Antibodies) lysine 4 tri (show VANGL2 Antibodies)-methylation in mantle cell lymphoma

Mouse (Murine) Lysine (K)-Specific Demethylase 5B (KDM5B) interaction partners

  1. data suggest Kdm5b negatively regulates neurogenesis and represses reelin (show RELN Antibodies) in neural stem cells from the adult subventricular zone.

  2. These results suggest that KDM5B acts to repress type I IFN and other innate cytokines to promote an altered immune response following Respiratory syncytial virus infection that contributes to development of chronic disease.

  3. findings demonstrate that dissociation of the GAPDH/Siah1 pro-apoptotic complex can block high glucose-induced pericyte apoptosis, widely considered a hallmark feature of DR

  4. Deletion of Jarid1b compromises hematopoietic stem cell (HSC (show FUT1 Antibodies)) self-renewal capacity; Jarid1b is a positive regulator of HSC (show FUT1 Antibodies) potential.

  5. Mechanistically, JARID1B was required for GATA3 (show GATA3 Antibodies) recruitment to the Foxa1 (show FOXA1 Antibodies) promoter to activate Foxa1 (show FOXA1 Antibodies) expression.

  6. KDM5B is a barrier to the reprogramming process as evidenced by the accelerated reprogramming of differentiated cells in the absence of Kdm5b.

  7. these studies identified Jarid1b as a negative regulator of hematopoietic stem cell (HSC (show FUT1 Antibodies)) activity and Jhdmlf as a positive regulator of HSC (show FUT1 Antibodies) activity.

  8. Results suggest a role for Jarid1b in Rb-mediated repression of cell cycle genes during senescence.

  9. results delineate an essential role for Jarid1b-mediated transcriptional control during embryonic stem cell differentiation

  10. The present study demonstrated a functional contribution of PLU1 overexpression with concomitant epigenetic dysregulation in cancer progression.

Pig (Porcine) Lysine (K)-Specific Demethylase 5B (KDM5B) interaction partners

  1. KDM5B is required for porcine embryo development through regulating the balance of bivalent H3K4me3-H3K27me3 modifications.

Cow (Bovine) Lysine (K)-Specific Demethylase 5B (KDM5B) interaction partners

  1. Histone demethylases KDM3A (show KDM3A Antibodies), KDM4A (show KDM4A Antibodies), and KDM4C (show KDM4C Antibodies) were expressed before and after embryonic genome activation, whereas KDM5B was mainly expressed during the blastocyst period.

KDM5B Antigen Profile

Protein Summary

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor (By similarity).

Gene names and symbols associated with KDM5B

  • lysine (K)-specific demethylase 5Ba (kdm5ba) antibody
  • lysine (K)-specific demethylase 5Bb (kdm5bb) antibody
  • lysine (K)-specific demethylase 5B (KDM5B) antibody
  • lysine (K)-specific demethylase 5B (Kdm5b) antibody
  • 2010009J12Rik antibody
  • 2210016I17Rik antibody
  • AW556288 antibody
  • cb264 antibody
  • CT31 antibody
  • D1Ertd202e antibody
  • id:ibd5050 antibody
  • Jarid1b antibody
  • jarid1ba antibody
  • jarid1bb antibody
  • mKIAA4034 antibody
  • PLU-1 antibody
  • Plu1 antibody
  • PUT1 antibody
  • Rb-Bp2 antibody
  • RBBP2H1A antibody
  • RGD1565602 antibody
  • wu:fc44h11 antibody
  • wu:fd15c05 antibody
  • zgc:85741 antibody

Protein level used designations for KDM5B

jumonji, AT rich interactive domain 1B (Rbp2 like) , jumonji, AT rich interactive domain 1Ba (Rbp2 like) , histone demethylase JARID1B-B , jumonji/ARID domain-containing protein 1B-B , lysine-specific demethylase 5B-B , putative DNA/chromatin binding motif , lysine (K)-specific demethylase 5B , Jumonji, AT rich interactive domain 1B (RBP2-like) , jumonji, AT rich interactive domain 1B , lysine-specific demethylase 5B-like , RBP2-H1 , cancer/testis antigen 31 , histone demethylase JARID1B , jumonji/ARID domain-containing protein 1B , lysine-specific demethylase 5B , retinoblastoma-binding protein 2 homolog 1 , retinoblastoma-binding protein 2, homolog 1A , putative DNA/chromatin binding motif 1

GENE ID SPECIES
327168 Danio rerio
415256 Danio rerio
457630 Pan troglodytes
100011885 Monodelphis domestica
100064707 Equus caballus
100077577 Ornithorhynchus anatinus
100356218 Oryctolagus cuniculus
100483283 Ailuropoda melanoleuca
10765 Homo sapiens
75605 Mus musculus
421168 Gallus gallus
479999 Canis lupus familiaris
100625438 Sus scrofa
540633 Bos taurus
304809 Rattus norvegicus
100723111 Cavia porcellus
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