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anti-Lysine (K)-Specific Demethylase 6A (KDM6A) Antibodies

KDM6A is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. Additionally we are shipping KDM6A Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KDM6A 7403 O15550
KDM6A 22289 O70546
KDM6A 100310845  
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Top anti-KDM6A Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-UTX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-UTX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate WB Suggested Anti-UTX  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IF, ELISA, WB KDM6A monoclonal antibody (M05), clone 4E7. Western Blot analysis of KDM6A expression in HepG2. Detection limit for recombinant GST tagged KDM6A is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB Western Blot showing Utx antibody used at a concentration of 1.0 ug/ml against Mouse Intestine Lysate 50 μg Log in to see 7 to 9 Days
$510.36
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB   50 μg Log in to see 8 to 9 Days
$210.22
Details

KDM6A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
,
,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-KDM6A Antibodies

  1. Dog (Canine) Polyclonal KDM6A Primary Antibody for WB - ABIN2781142 : Hong, Cho, Yu, Yu, Veenstra, Ge: Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against KDM6A Interaction Partners

Human Lysine (K)-Specific Demethylase 6A (KDM6A) interaction partners

  1. UTX positively regulates E-cadherin (show CDH1 Antibodies) expression in colon cancer cells.

  2. UTX is a prominent tumour suppressor that functions as a negative regulator of EMT (show ITK Antibodies)-induced Cancer Stem Cell-like properties by epigenetically repressing epithelial-mesenchymal transition -TFs.

  3. Kabuki syndrome may be caused by mutations in one of two histone methyltransferase genes: KMT2D (show MLL2 Antibodies) and KDM6A.

  4. Our results provide further support for the similar roles of KMT2D (show MLL2 Antibodies) and KDM6A in the etiology of KS by using a vertebrate model organism to provide direct evidence of their roles in the development of organs and tissues affected in KS patients.

  5. Turner Syndrome subjects, who are predisposed to chronic ear infections, had reduced UTX expression in immune cells and decreased circulating CD4(+) CXCR5(+) T cell frequency.

  6. A report of novel KDM6A mutations in patients with Kabuki syndrome.

  7. The KDM6A gene is a histone demethylase (show MBD2 Antibodies) specific for histone H3 (show HIST3H3 Antibodies) Lysin 27 and regulates gene transcription [35]. In approximately 24% of urothelial carcinoma, KDM6A is altered.

  8. This study is the first to identify frequent BAP1 (show RNF2 Antibodies) and BRCA pathway alterations in bladder cancer, show TERT (show TERT Antibodies) promoter alterations are independent of other bladder cancer gene alterations, and show KDM6A loss is a driver of the bladder cancer phenotype.

  9. One girl had a novel splice-site mutation in KDM6A.

  10. Mutations in KMT2D (show MLL2 Antibodies) gene were identified in 10/16 (62%) of the patients, whereas none of the patients had KDM6A mutations.

Mouse (Murine) Lysine (K)-Specific Demethylase 6A (KDM6A) interaction partners

  1. a critical role for the enzymatic activity of UTX in activating muscle-specific (show EIF3K Antibodies) gene expression during myofiber regeneration and have revealed a physiological role for active H3K27 demethylation in vivo.

  2. Results propose that Utx plays important roles in osteoblast differentiation by controlling the expressions of Runx2 (show RUNX2 Antibodies) and Osterix (show SP7 Antibodies).

  3. Utx is required for T-cell development.

  4. Genome-wide association between Six4 (show SIX4 Antibodies), MyoD (show MYOD1 Antibodies), and the histone demethylase Utx during myogenesis.

  5. Mice with a T-cell-specific UTX deletion had fewer Tfh cells, reduced germinal center responses, no virus-specific IgG, inability to resolve chronic LCMV infections, and decreased expression of IL-6-receptor-alpha (show IL6R Antibodies) and other Tfh cell-related genes.

  6. UTX may play a potential role in regulation of brown adipocyte gene expression

  7. Utx and Jmjd3 (show Kdm6b Antibodies) mutant mouse embryonic fibroblasts (MEFs) demonstrate dramatic loss of H3K27me3 from promoters of several Hox (show MSH2 Antibodies) genes and transcription factors.

  8. Inhibition of histone demethylases UTX and JMJD3 (show Kdm6b Antibodies) inhibits HSV-1 reactivation from sensory neurons.

  9. H3K27me3 demethylase (show MBD2 Antibodies) UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

  10. JMJD3 (show Kdm6b Antibodies) is essential for the initiation and maintenance of T-ALL, as it controls important oncogenic gene targets by modulating H3K27 methylation; by contrast, UTX functions as a tumour suppressor and is frequently genetically inactivated in T-ALL

KDM6A Antigen Profile

Protein Summary

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3.

Gene names and symbols associated with KDM6A

  • lysine (K)-specific demethylase 6A (KDM6A) antibody
  • lysine (K)-specific demethylase 6A (Kdm6a) antibody
  • bA386N14.2 antibody
  • KABUK2 antibody
  • RGD1565481 antibody
  • Utx antibody
  • Uty antibody

Protein level used designations for KDM6A

lysine (K)-specific demethylase 6A , bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)) , histone demethylase UTX , lysine-specific demethylase 6A , ubiquitously transcribed tetratricopeptide repeat protein X-linked , ubiquitously-transcribed TPR gene on the X chromosome , ubiquitously-transcribed TPR protein on the X chromosome , ubiquitously transcribed tetratricopeptide repeat, X chromosome , 4lysine (K)-specific demethylase 6A , ubiquitously transcribed TPR protein on the X chromosome , ubiquitously transcribed X chromosome tetratricopeptide repeat protein , ubiquitously transcribed tetratricopeptide repeat gene, X chromosome , ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome

GENE ID SPECIES
100081798 Ornithorhynchus anatinus
100539898 Meleagris gallopavo
100592229 Nomascus leucogenys
7403 Homo sapiens
491845 Canis lupus familiaris
22289 Mus musculus
100310845 Rattus norvegicus
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