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anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) Antibodies

Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Additionally we are shipping and Kdm6b Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Kdm6b 216850 Q5NCY0
Kdm6b 23135 O15054
Kdm6b 363630  
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Top anti-Kdm6b Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-JMJD3 C-term Pab (ABIN387863) in untransfected 293 cells (left) and transfected 293 cells (right). The detection of a prominent band at 180kDa is observed on transfected 293 cells but not on the untransfected 293 cells. Data kindly provided by Dr.Gioacchino Natoli of European Institute of Oncology. Formalin-fixed and paraffin-embedded human Skeletal Muscle tissue reacted with JMJD3 Antibody(C-term)(ABIN387863), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of anti-JMJD3 N-term Pab (ABIN387862) in Hela cell line lysates. JMJD3 N-term(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with JMJD3 N-term (ABIN387862), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-JMJD3 Center Pab (ABIN387864) in Hela cell line lysates. JMJD3 Center(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of JMJD3 in K562 cells with JMJD3 antibody at 2.5 ug/mL. Western blot analysis of JMJD3 in K562 cell lysate with JMJD3 Antibody  at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Mouse Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-JMJD3 Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate Host: Rabbit  Target Name: JMJD3  Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 2.5 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration:.%-18 % 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

Kdm6b Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)


Top referenced anti-Kdm6b Antibodies

  1. Human Polyclonal Kdm6b Primary Antibody for IF, IHC (p) - ABIN387862 : Lu, Lu, Liao, Yu, Chung, Kao, Wu: Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 13 references for ABIN387862

  2. Mouse (Murine) Polyclonal Kdm6b Primary Antibody for IHC (p), WB - ABIN387863 : Das, Jung, Chai: The role of NF-kappaB and H3K27me3 demethylase, Jmjd3, on the anthrax lethal toxin tolerance of RAW 264.7 cells. in PLoS ONE 2010 (PubMed)
    Show all 5 references for ABIN387863

  3. Human Polyclonal Kdm6b Primary Antibody for EIA, IF - ABIN1450111 : De Santa, Totaro, Prosperini, Notarbartolo, Testa, Natoli: The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. in Cell 2007 (PubMed)
    Show all 3 references for ABIN1450111

  4. Human Polyclonal Kdm6b Primary Antibody for WB - ABIN387864 : Shaw, Martin: Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes. in EMBO reports 2009 (PubMed)

  5. Dog (Canine) Polyclonal Kdm6b Primary Antibody for WB - ABIN2778610 : Hong, Cho, Yu, Yu, Veenstra, Ge: Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against Kdm6b Interaction Partners

Zebrafish Lysine (K)-Specific Demethylase 6B (Kdm6b) interaction partners

  1. Data demonstrate that histone modifications silence promoters of numerous genes involved in zebrafish caudal (show CAD Antibodies) fin regeneration, and that Kdm6b.1 may be the histone demethylase (show MBD2 Antibodies) required during regeneration.

Mouse (Murine) Lysine (K)-Specific Demethylase 6B (Kdm6b) interaction partners

  1. JMJD3 up-regulation and NF-kappaB (show NFKB1 Antibodies) activation occur in the region of the wound edge during keratinocyte wound healing

  2. these studies established a critical role of Jmjd3-mediated H3K27 demethylation in Th17 cell differentiation and suggest that Jmjd3 can be a novel therapeutic target for suppressing autoimmune responses.

  3. These results strongly demonstrated that JMJD3 is required for osteoblast differentiation and bone formation in mice.

  4. APN (show ANPEP Antibodies) can help to reduce periodontitis-related bone loss, modulate JMJD3 and IRF4 (show IRF4 Antibodies) expression, and macrophage infiltration.

  5. JMJD3 is an epigenetic regulator in development and disease. (Review)

  6. Jmjd3 is required for T-cell development.

  7. Jmjd3-catalyzed erasure of H3K27me3 is required for brown fat gene expression and browning of white fat.

  8. Utx (show KDM6A Antibodies) and Jmjd3 mutant mouse embryonic fibroblasts (MEFs) demonstrate dramatic loss of H3K27me3 from promoters of several Hox (show MSH2 Antibodies) genes and transcription factors.

  9. Jmjd3 is an epigenetic factor in T-cell differentiation via changes in histone methylation and target gene expression.

  10. JMJD3 is a key epigenetic regulator in the process of cartilage maturation during endochondral bone formation.

Human Lysine (K)-Specific Demethylase 6B (Kdm6b) interaction partners

  1. Low JMJD3 expression is associated with Colorectal Cancer.

  2. JMJD3 up-regulation and NF-kappaB (show NFKB1 Antibodies) activation occur in the region of the wound edge during keratinocyte wound healing

  3. JMJD3 promotes SAHF formation by demethylating RB at K810, which reduce the level of phosphorylation of RB protein at S807/811, and this interplay promotes the formation of senescence-associated heterochromatin foci in senescent WI38 cells.

  4. We demonstrate that KDM6B plays a key role in clear cell renal cell carcinoma (show MOK Antibodies)

  5. Jmjd3 regulates osteoblast apoptosis through targeting Bcl-2 (show BCL2 Antibodies) expression and Bim (show BCL2L11 Antibodies) phosphorylation.

  6. Findings reveal a novel epigenetic mechanism by which JMJD3 promotes melanoma progression and metastasis.

  7. JMJD3 is an epigenetic regulator in development and disease. (Review)

  8. KDM6B may act in a pro-apoptotic role in NSCLC.

  9. Demethylation of IGFBP5 (show IGFBP5 Antibodies) by Histone Demethylase (show MBD2 Antibodies) KDM6B Promotes Mesenchymal Stem Cell-Mediated Periodontal Tissue Regeneration by Enhancing Osteogenic Differentiation and Anti-Inflammation Potentials.

  10. Data indicate a reverse correlation between the mRNA levels of histone H3 (show HIST3H3 Antibodies) lysine-27 demethylase (show MBD2 Antibodies) (JMJD3) and global histone h3 (show HIST3H3 Antibodies) lysine 27 methylation (H3K27me3).

Kdm6b Antigen Profile

Protein Summary

Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

Gene names and symbols associated with Kdm6b

  • jumonji domain containing 3 (jmjd3) antibody
  • lysine (K)-specific demethylase 6B (KDM6B) antibody
  • lysine (K)-specific demethylase 6B, b (kdm6bb) antibody
  • lysine (K)-specific demethylase 6B (LOC100140276) antibody
  • lysine (K)-specific demethylase 6B (LOC100343083) antibody
  • KDM1 lysine (K)-specific demethylase 6B (Kdm6b) antibody
  • lysine (K)-specific demethylase 6B (Kdm6b) antibody
  • 1700064E03Rik antibody
  • BC038313 antibody
  • JMJD3 antibody
  • kdm6b antibody
  • mKIAA0346 antibody
  • si:ch211-237l4.7 antibody

Protein level used designations for Kdm6b

jumonji domain containing 3 , lysine (K)-specific demethylase 6B , jumonji domain containing 3, histone lysine demethylase , lysine-specific demethylase 6B-like , jmjC domain-containing protein 3 , jumonji domain-containing protein 3 , lysine-specific demethylase 6B , lysine demethylase 6B , jumonji domain-containing 3

GENE ID SPECIES
779446 Xenopus (Silurana) tropicalis
468438 Pan troglodytes
563644 Danio rerio
716348 Macaca mulatta
100414637 Callithrix jacchus
100140276 Bos taurus
100343083 Oryctolagus cuniculus
216850 Mus musculus
23135 Homo sapiens
489481 Canis lupus familiaris
363630 Rattus norvegicus
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