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Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Additionally we are shipping KDM3B Antibodies (100) and many more products for this protein.
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findings indicate that Kdm3b is required for normal spermatogenesis and sexual behaviors in male mice
These results demonstrate that Kdm3b-mediated H3K9 demethylation plays essential roles in maintenance of the circulating IGF-1 (show IGF1 Proteins), postnatal somatic growth, circulating 17beta-estradiol, and female reproductive function.
H3K9 demethylase (show MBD2 Proteins) KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1 (show ANGPT1 Proteins).
High expression of KDM3B and KDM5A (show KDM5A Proteins) is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients.
evidence that the H3K9-me1 (show ME1 Proteins)/2 demethylase (show MBD2 Proteins) KDM3B might play a role in leukemogenesis via activation of lmo2 (show LMO2 Proteins) through interdependent actions with the histone acetyltransferase complex containing CBP (show CREBBP Proteins)
A novel nuclear protein (show RDBP Proteins), 5qNCA is a candidate for the myeloid leukemia (show BCL11A Proteins) tumor suppressor gene on chromosome 5 band q31.
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
lysine (K)-specific demethylase 3B
, jumonji domain containing 1B
, lysine-specific demethylase 3B-like
, jmjC domain-containing histone demethylation protein 2B
, jumonji domain-containing protein 1B
, lysine-specific demethylase 3B
, nuclear protein 5qNCA