anti-Lysine (K)-Specific Demethylase 4B (KDM4B) Antibodies

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
KDM4B 23030 O94953
KDM4B 193796 Q91VY5
KDM4B    
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Top anti-KDM4B Antibodies at antibodies-online.com

Showing 10 out of 145 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-JMJD2B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human kidney WB Suggested Anti-JMJD2B <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Human kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB <b>WB Suggested Anti-JMJD2B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB JMJD2B Antibody (N-term) (ABIN655890) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the JMJD2B antibody detected the JMJD2B protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of Phospho-JMJD2B-pT305 (ABIN653576) in MDA-MB435 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. Western blot analysis of Phospho-JMJD2B-pT305 (ABIN653576) in NIH-3T3 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of JMJD2B Antibody (N-term) (ABIN653341) in K562 cell line lysates (35 µg/lane). JMJD2B (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of JMJD2B Antibody (N-term) in A375 cell line lysates (35ug/lane). This demonstrates the JMJD2B antibody detected the JMJD2B protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Phospho-JMJD2B-pT305 in MDA-MB435 cell line lysates (35ug/lane). JMJD2B (arrow) was detected using the purified Pab. Western blot analysis of Phospho-JMJD2B-pT305 in NIH-3T3 cell line lysates (35ug/lane). JMJD2B (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of K562 cells using JMJD2B Antibody (N-term) Cat.-No AP52269PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human Testis tissue reacted with JMJD2B Antibody (N-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IP, WB Western Blot: JMJD2B Antibody [ABIN2616825] - Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Dilution used for WB at 0.5 ug/ml. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 20 Days
$375.38
Details

KDM4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-KDM4B Antibodies

  1. Human Polyclonal KDM4B Primary Antibody for IP, WB - ABIN261682 : Beyer, Kristensen, Jensen, Johansen, Staller: The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. in The Journal of biological chemistry 2008 (PubMed)
    Show all 3 Pubmed References

  2. Chicken Polyclonal KDM4B Primary Antibody for ChIP, IP - ABIN261681 : Uribe, Buzzi, Bronner, Strobl-Mazzulla: Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression. in The Journal of cell biology 2015 (PubMed)

  3. Human Polyclonal KDM4B Primary Antibody for EIA, WB - ABIN952974 : Pollard, Loenarz, Mole, McDonough, Gleadle, Schofield, Ratcliffe: Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. in The Biochemical journal 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal KDM4B Primary Antibody for EIA, FACS - ABIN952973 : Katoh, Katoh: Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells. in International journal of molecular medicine 2007 (PubMed)
    Show all 5 Pubmed References

More Antibodies against KDM4B Interaction Partners

Human Lysine (K)-Specific Demethylase 4B (KDM4B) interaction partners

  1. This is the first demonstration that a Jumonji (show JARID2 Antibodies)-domain histone demethylase (show MBD2 Antibodies) regulates cellular processes required for peritoneal dissemination of cancer cells, one of the predominant factors affecting prognosis of EOC. The pathways regulated by KDM4B may present novel opportunities to develop combinatorial therapies to improve existing therapies for EOC patients.

  2. identification of JMJD2B/KDM4B as a p53 (show TP53 Antibodies)-inducible gene in response to DNA damage.

  3. KDM4B and KDM4D (show KDM4D Antibodies) expression may associate with an aggressive subtype of classical Hodgkin lymphoma and be linked with radioresistance

  4. KDM4B is a key mediator in epithelial-mesenchymal transition process, and may serve as an important prognostic marker and therapeutic target for the metastatic progression of human pancreatic cancer

  5. The overall survival (OS) of the 50 JMJD2B-positive patients after surgery was significantly inferior to that of the JMJD2B-negative patients (five-year survival=56.7% vs. 92.6%; log-rank: p=0.01). Multivariate analysis showed that JMJD2B positivity was an independent prognostic factor. CONCLUSION: JMJD2B may be a novel prognostic factor for resected lung adenocarcinoma

  6. upon TGF-beta (show TGFB1 Antibodies) stimulation, KDM4B was recruited to the SOX9 (show SOX9 Antibodies) promoter, removed the silencing H3K9me3 marks, and activated the transcription of SOX9 (show SOX9 Antibodies).

  7. High KDM4B expression is associated with endometrial cancer progression.

  8. JMJD2B and JMJD2C (show KDM4C Antibodies) play an important role in the pathology of osteosarcoma via the up-regulation of FGF2 (show FGF2 Antibodies).

  9. results reveal that JMJD2B is dramatically upregulated in hepatocellular carcinoma, making it a potential diagnostic marker for the further development of HCC (show FAM126A Antibodies) treatment therapies

  10. Functional studies demonstrated that KDM4B regulates the Myc (show MYC Antibodies) pathway. N-Myc (show MYCN Antibodies) was found to physically interact with and recruit KDM4B. KDM4B was found to regulate neuroblastoma (show ARHGEF16 Antibodies) cell proliferation and differentiation in vitro and xenograft growth in vivo.

Mouse (Murine) Lysine (K)-Specific Demethylase 4B (KDM4B) interaction partners

  1. results indicate that JMJD2B regulates PPARgamma (show PPARG Antibodies) and C/EBPalpha (show CEBPA Antibodies) during adipogenesis

  2. JMJD2B-deficient mice exhibited hyperactive behavior, sustained hyperactivity in a novel environment, deficits in working memory and spontaneous epileptic-like seizures.

  3. KDM4B histone demethylase (show MBD2 Antibodies) regulates expression of myogenic regulators such as MyoD (show MYOD1 Antibodies) and thereby controls myogenic differentiation of C2C12 myoblast cells.

  4. Jmjd2b unique, Jmjd2c (show KDM4C Antibodies) unique, and Jmjd2b-Jmjd2c (show KDM4C Antibodies) common target sites belong to functionally separable Core, Polycomb (show CBX2 Antibodies) repressive complex (PRC (show PPRC1 Antibodies)), and Myc (show MYC Antibodies) regulatory modules, respectively.

  5. This study establishes novel Jmjd2b targets that potentiate a biological rationale involving Jmjd2b in NSC inflammation.

  6. The promoter of Kdm4b is bound and activated by C/EBPbeta (show CEBPB Antibodies)

  7. Induction of Jmjd2b in the embryonic stem cells decreased total levels of histone-3 lysine-9 trimethylation (H3K9me3) by 63%.

  8. Data indicate that Myst4 (show KAT6B Antibodies), Jmjd2b, Aof1 (show KDM1B Antibodies) genes are regulated by H3K9me under hyperinsulinemia/hyperglycemia.

  9. A subgroup of murine Jmjd2 (show KDM4A Antibodies) proteins antagonize H3K9me3 at pericentric heterochromatin.

KDM4B Antigen Profile

Protein Summary

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Gene names and symbols associated with KDM4B

  • lysine (K)-specific demethylase 4B (KDM4B) antibody
  • lysine (K)-specific demethylase 4B (kdm4b) antibody
  • lysine (K)-specific demethylase 4B (Kdm4b) antibody
  • 4732474L06Rik antibody
  • Jmjd2b antibody
  • KDM4B antibody
  • mKIAA0876 antibody
  • si:ch211-124a3.4 antibody
  • TDRD14B antibody

Protein level used designations for KDM4B

lysine (K)-specific demethylase 4B , jumonji domain containing 2B , lysine-specific demethylase 4B , lysine-specific demethylase 4B-like , jmjC domain-containing histone demethylation protein 3B , jumonji domain-containing protein 2B , tudor domain containing 14B

GENE ID SPECIES
455614 Pan troglodytes
556504 Danio rerio
100023921 Monodelphis domestica
100511181 Sus scrofa
100541123 Meleagris gallopavo
100563051 Anolis carolinensis
100582140 Nomascus leucogenys
23030 Homo sapiens
193796 Mus musculus
476741 Canis lupus familiaris
508141 Bos taurus
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