Lysocardiolipin Acyltransferase 1 (LCLAT1) ELISA Kits

Acyl-CoA:lysocardiolipin acyltransferase. Additionally we are shipping Lysocardiolipin Acyltransferase 1 Antibodies (18) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human LCLAT1 LCLAT1 253558 Q6UWP7
Anti-Mouse LCLAT1 LCLAT1 225010 Q3UN02
Anti-Rat LCLAT1 LCLAT1 362702  
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More ELISA Kits for Lysocardiolipin Acyltransferase 1 Interaction Partners

Zebrafish Lysocardiolipin Acyltransferase 1 (LCLAT1) interaction partners

  1. Data indicate that lycat is the earliest known player in the generation of both endothelial and hematopoietic lineages.

Human Lysocardiolipin Acyltransferase 1 (LCLAT1) interaction partners

  1. LYCAT expression was significantly altered in PBMCs and lung tissues from patients with idiopathic pulmonary fibrosis.

  2. Data show that ALCAT1 possesses acyltransferase activities toward lysophosphatidylinositol and lysophosphatidylglycerol, and identify critical amino acids that are potentially involved in lysophospholipid substrate binding.

Mouse (Murine) Lysocardiolipin Acyltransferase 1 (LCLAT1) interaction partners

  1. Alcat1 is destabilized in epithelia by lipopolysaccharide (LPS (show TLR4 ELISA Kits)) impairing mitochondrial function.

  2. Differential reduction in cardiac and liver monolysocardiolipin acyltransferase-1 and reduction in cardiac and liver tetralinoleoyl-cardiolipin in the alpha-subunit (show POLG ELISA Kits) of trifunctional protein heterozygous knockout mice

  3. pathological cardiolipin remodeling by ALCAT1 linked to the pathogenesis of nonalcoholic fatty liver diseases

  4. LYCAT expression was altered in peripheral blood mononuclear cells and outcome in pulmonary fibrosis.

  5. findings implicate a key role of ALCAT1 as the missing link between oxidative stress and mitochondrial dysfunction in the etiology of age-related heart diseases

  6. overexpression of ALCAT1 causes mitochondrial fragmentation through oxidative stress and depletion of mitofusin mitofusin (show MFN2 ELISA Kits) 2 (MFN2 (show MFN2 ELISA Kits)) expression

  7. Data indicate that LYCAT is a determinant of PI molecular species and its function is conserved in C. elegans and mammals.

  8. ALCAT1 deficiency prevented the onset of DIO and significantly improved mitochondrial complex I activity, lipid oxidation, and insulin (show INS ELISA Kits) signaling.

  9. Expression of Lclat1 gene in the mouse cardiovascular system is reported.

  10. identification and characterization of a gene that encodes an acyl-CoA:lysocardiolipin acyltransferase 1

Lysocardiolipin Acyltransferase 1 (LCLAT1) Antigen Profile

Antigen Summary

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.

Gene names and symbols associated with LCLAT1

  • lysocardiolipin acyltransferase 1 (lclat1) antibody
  • lysocardiolipin acyltransferase 1 (LCLAT1) antibody
  • lysocardiolipin acyltransferase 1 (Lclat1) antibody
  • 1AGPAT8 antibody
  • Agpat8 antibody
  • AGPATP8 antibody
  • AI181996 antibody
  • Alcat1 antibody
  • Gm91 antibody
  • HSRG1849 antibody
  • lclat1 antibody
  • Lycat antibody
  • RGD1565906 antibody
  • UNQ1849 antibody
  • wu:fj17g04 antibody
  • zgc:77380 antibody

Protein level used designations for LCLAT1

lysocardiolipin acyltransferase 1 , 1-acylglycerol-3-phosphate O-acyltransferase 8 , 1-AGP acyltransferase 8 , 1-AGPAT 8 , acyl-CoA:lysocardiolipin acyltransferase 1

406554 Danio rerio
459129 Pan troglodytes
483023 Canis lupus familiaris
520912 Bos taurus
704859 Macaca mulatta
100031432 Monodelphis domestica
100070805 Equus caballus
100079134 Ornithorhynchus anatinus
100216057 Xenopus (Silurana) tropicalis
100217396 Sus scrofa
100345148 Oryctolagus cuniculus
100412652 Callithrix jacchus
100476509 Ailuropoda melanoleuca
100594929 Nomascus leucogenys
253558 Homo sapiens
225010 Mus musculus
362702 Rattus norvegicus
421303 Gallus gallus
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