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Lysophosphatidic Acid Receptor 3 Proteins (LPAR3)

LPAR3 encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. Additionally we are shipping LPAR3 Antibodies (81) and LPAR3 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LPAR3 23566 Q9UBY5
LPAR3 65086 Q9EQ31
Rat LPAR3 LPAR3 66025 Q8K5E0
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Top LPAR3 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details

LPAR3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Lysophosphatidic Acid Receptor 3 (LPAR3) Interaction Partners

Pig (Porcine) Lysophosphatidic Acid Receptor 3 (LPAR3) interaction partners

  1. EDG4 (show LPAR2 Proteins) and EDG7 map to q2.1 of pig chromosome 2 (SSC2 (show ELOVL2 Proteins)) and q2.6-3.2 of pig chromosome6 (SSC6), respectively

  2. EDG7 was regulated by pregnancy stage and status. EDG7 expression was highest on d 12 pregnancy, and localized to the luminal and glandular epithelium, and EDG7 mRNA levels were elevated by estrogen in the endometrium.

Human Lysophosphatidic Acid Receptor 3 (LPAR3) interaction partners

  1. These data indicated that the expression of LPA receptor 3 was increased in human triple-negative breast cancers and is associated with tumor metastatic ability.

  2. Suggest that LPA2 (show LPAR2 Proteins) and LPA3 may function as a molecular switch and play opposing roles during megakaryopoiesis of K562 cells.

  3. The results demonstrate LPA (show APOA Proteins)-stimulated migration in oral carcinoma cells through LPAR3, mediated further by PKC (show PRRT2 Proteins), which acts either in concert with or independently of EGFR (show EGFR Proteins) transactivation

  4. Findings indicate lysophosphatidic acid (LPA (show APOA Proteins))-lysophosphatidic acid receptor-Galpha13 (show GNA13 Proteins) signaling node as a therapeutic target for pancreatic cancer treatment and control.

  5. LPA3 mRNA is clearly expressed in human PANC-1 tumor cells.

  6. Lysophosphatidic acid (LPA) increased hepatocellular carcinoma cells cell invasion, which was LPA-receptor dependent.

  7. in the normal human menstrual cycle, lysophosphatidic acid receptor 3 messenger RNA and protein expression change, indicating that this gene may be related to the function of the endometrium.

  8. The results indicated that LPA(3) acts as a positive regulator of cell motility and invasion in sarcoma cells, suggesting that LPA (show APOA Proteins) signaling pathway via LPA(3) may be involved in the progression of sarcoma cells.

  9. High LPAR3 expression is associated with aggressiveness of breast carcinoma.

  10. LPA3 Receptor act as a negative regulator on cell motile and invasive abilities of colon cancer.

Mouse (Murine) Lysophosphatidic Acid Receptor 3 (LPAR3) interaction partners

  1. Lpar3(-/-) female mice had delayed embryo implantation.

  2. These results suggest that LPA3 receptor-mediated amplification of spinal LPA production is required for the development of paclitaxel-induced neuropathic pain.

  3. These results suggest that LPA signaling through LPA3 may inhibit angiogenesis and fibroblast activation in mouse lung cancer cells

  4. The thromboxane A(2) receptor agonist 11-deoxy PGF (show PTGFR Proteins)(2alpha) can partially alleviate embryo crowding in the Lpar3((-/-)) females and embryo crowding likely contributes to reduced litter size in the Lpar3((-/-)) females.

  5. Lysophosphatidic acid, via LPA(1 (show LPAR1 Proteins)) and LPA(3) receptors, may play a significant role in inducing and/or sustaining the massive infiltration of leukocytes during inflammation

  6. Luminal epithelium localization and up-regulation by progesterone differentiate LPA3 from the other nine LP receptors and may underlie its essential role in embryo implantation.

  7. LPA(1 (show LPAR1 Proteins)-3) are differentially expressed in the central nervous system and their expression is upregulated in response to injury.

  8. Lysophosphatidic acid receptors LPA3 and LPA1 (show LPAR1 Proteins) promote CXCL12 (show CXCL12 Proteins)-mediated smooth muscle progenitor cell recruitment.

  9. LPA3 receptor-mediated signalling has an influence on embryo implantation, and there is a linkage between LPA signalling and prostaglandin biosynthesis.

  10. Progesterone and estrogen cooperatively regulate LPA(3) expression, thereby contributing to the receptivity of uteri during early pregnancy.

LPAR3 Protein Profile

Protein Summary

This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.

Gene names and symbols associated with LPAR3

  • lysophosphatidic acid receptor 3 (LPAR3)
  • lysophosphatidic acid receptor 3 (LOC100038016)
  • lysophosphatidic acid receptor 3 (Lpar3)
  • Edg-7 protein
  • Edg7 protein
  • GPCR protein
  • HOFNH30 protein
  • LP-A3 protein
  • lpA3 protein
  • RP4-678I3 protein

Protein level used designations for LPAR3

endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7 , lysophosphatidic acid receptor 3 , LPA receptor 3 , LPA receptor EDG7 , LPA-3 , calcium-mobilizing lysophosphatidic acid receptor LP-A3 , endothelial cell differentiation gene 7 , lysophosphatidic acid receptor Edg-7 , endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 7 , putative G protein-coupled receptor snGPCR32 , snGPCR32

GENE ID SPECIES
532829 Bos taurus
490187 Canis lupus familiaris
710828 Macaca mulatta
736110 Pan troglodytes
771215 Gallus gallus
100038016 Sus scrofa
100113360 Sus scrofa
100448001 Pongo abelii
23566 Homo sapiens
65086 Mus musculus
66025 Rattus norvegicus
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