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The protein encoded by LPAR6 belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. Additionally we are shipping LPAR6 Antibodies (40) and many more products for this protein.
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LPA2 mRNA levels were associated with poorer differentiation, and higher LPA6 levels were associated with microvascular invasion in HCC; both became a risk factor for recurrence after surgical treatment when combined with increased serum ATX levels
LPAR6 has a role in tumorigenicity of hepatocellular carcinoma
These results suggest that the diverse roles of LPA4 (show LPAR4 Proteins), LPA5 (show LPAR5 Proteins) and LPA6 are involved in the activation of tumor progression in pancreatic cancer cells.
Missense mutations in LPAR6 reveal abnormal phospholipid signaling pathways leading to hypotrichosis.
We have identified a novel deletion mutation in LPAR6, which was responsible for autosomal woolly hair syndrome with hypotrichosis in a consanguineous Chinese family.
study extends the spectrum of mutations in LPAR6/P2RY5 gene and underscores those mutations in LPAR6/P2RY5 and LIPH (show LIPC Proteins) result in similar phenotypes
LPA2 (show LPAR2 Proteins) and LPA6 receptor subtypes are predominant in both HPAECs and HMVECs
These findings extend the spectrum of known LPAR6 mutations and suggest a founder effect of the p.G146R mutation in the Pakistani population
homozygous loss of the entire LPAR6 gene in a Turkish family with hypotrichosis and woolly hair
Mutations identified in the present study extend the body of evidence implicating LPAR6 and LIPH (show LIPC Proteins) genes in pathogenesis of human hereditary hair loss.
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants.
G-protein coupled purinergic receptor P2Y5
, purinergic receptor P2Y, G-protein coupled, 5
, lysophosphatidic acid receptor 6
, LPA receptor 6
, P2Y purinoceptor 5
, RB intron encoded G-protein coupled receptor
, oleoyl-L-alpha-lysophosphatidic acid receptor
, purinergic receptor 5
, purinergic receptor P2Y G protein-coupled protein 5
, purinergic receptor (family A group 5)
, G protein-coupled receptor