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anti-Lysyl Oxidase (LOX) Antibodies

The protein encoded by LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. Additionally we are shipping LOX Kits (40) and LOX Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LOX 4015 P28300
LOX 16948 P28301
LOX 24914 P16636
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Top anti-LOX Antibodies at antibodies-online.com

Showing 10 out of 184 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of 293 cells using  Lysyl oxidase Antibody (Center) Cat.-No AP52513PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of  Lysyl oxidase Antibody (Center) in MDA-MB468 cell line lysates (35ug/lane). LOX (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB LOX Antibody (Center)(Ascites) (ABIN1882261) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the LOX antibody detected the LOX protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB LOX Antibody (Center) (ABIN1882262) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the LOX antibody detected the LOX protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, ICC, IF, IP, SimWes, WB Flow Cytometry: LOX propeptide Antibody [NBP1-30327] - Staining of NTERA-2 cells using NP1-30327 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary antibody. Immunocytochemistry/Immunofluorescence: LOX propeptide Antibody [NBP1-30327] - Staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Cow Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Immunohistochemistry: LOX Antibody [ABIN250966] - Human placental villi, 40X. Staining of placental trophoblasts using ABIN250966 at 10 ug/ml. Detection of LOX in mouse kidney lysate using ABIN250966 (1:1,000). ECL detection was 15 sec. 0.05 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, WB Staining of LOX in mouse spleen using ABIN258622. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Staining of LOPP in mouse intestine using ABIN258371. Western Blot: LOX propeptide Antibody [ABIN2583718] - Detection of LOPP in MC3T3-E1 cell lysate. 0.1 mL Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, SimWes, WB Simple Western: LOX propeptide Antibody [NBP1-30012] - Simple Western lane view shows a specific band for LOX propeptide in 0.05 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Western Blot: LOX propeptide Antibody [NBP1-30012] - Western blot on cytoplasmic (c) and nuclear (n) extracts of NIH 3T3, ras-transformed (RS 485), PMEF and TGM-1 mouse fibroblast cells. 0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: LOX Antibody [ABIN4331347] - Analysis of LOX in human kidney Immunocytochemistry/Immunofluorescence: LOX Antibody [ABIN4331347] - LOX antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 7 to 9 Days
$408.19
Details

LOX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-LOX Antibodies

  1. Cow (Bovine) Polyclonal LOX Primary Antibody for ICC, IF - ABIN250966 : Wilhelmus, Bol, van Duinen, Drukarch: Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type. in Experimental gerontology 2013 (PubMed)
    Show all 10 references for ABIN250966

  2. Human Polyclonal LOX Primary Antibody for ICC, IHC (fro) - ABIN258622 : Jeay, Pianetti, Kagan, Sonenshein: Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. in Molecular and cellular biology 2003 (PubMed)
    Show all 7 references for ABIN258622

  3. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN258371 : Palamakumbura, Jeay, Guo, Pischon, Sommer, Sonenshein, Trackman: The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN258371

  4. Human Polyclonal LOX Primary Antibody for FACS, ICC - ABIN447477 : Sato, Trackman, Mäki, Myllyharju, Kirsch, Sonenshein: The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. in Molecular and cellular biology 2011 (PubMed)
    Show all 4 references for ABIN447477

  5. Human Monoclonal LOX Primary Antibody for WB - ABIN1882261 : Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN1882261

  6. Human Monoclonal LOX Primary Antibody for WB - ABIN1882262 : Santhanam, Baker, Hegamyer, Kirschmann, Colburn: Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. in Oncogene 2010 (PubMed)
    Show all 3 references for ABIN1882262

  7. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN440592 : Di Stefano, Torsello, Bianchi, Cifola, Mangano, Bovo, Cassina, De Marco, Corti, Meregalli, Bombelli, Viganò, Battaglia, Strada, Perego: Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures. in The American journal of pathology 2016 (PubMed)
    Show all 2 references for ABIN440592

  8. Human Polyclonal LOX Primary Antibody for EIA, FACS - ABIN953265 : Mariani, Trackman, Kagan, Eddy, Shows, Boyd, Deak: The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene). in Matrix (Stuttgart, Germany) 1992 (PubMed)

  9. Human Polyclonal LOX Primary Antibody for ICC, IF - ABIN4331347 : Contente, Yeh, Friedman: Tumor suppressive effect of lysyl oxidase proenzyme. in Biochimica et biophysica acta 2009 (PubMed)

More Antibodies against LOX Interaction Partners

Zebrafish Lysyl Oxidase (LOX) interaction partners

  1. Partial knockdown of lysyl oxidase genes sensitizes the developing embryo to dithiocarbamate exposure.

  2. Data reveal a role for lysyl oxidase in early morphogenesis, especially in muscle development and neurogenesis, and resume some aspects of physiopathology of copper metabolism.

Human Lysyl Oxidase (LOX) interaction partners

  1. LOX G473A polymorphism apparently elevated human sensitivity to cigarette smoking carcinogens for eliciting cancers in the lung and colon only. Thus, LOX G473A polymorphism positively correlates with carcinogenesis and it may be used as an ideal intrinsic biomarker for prediction or diagnosis of carcinogenesis in humans.

  2. increased cortisol and 11beta-HSD1 (show HSD11B1 Antibodies) abundance and decreased LOX abundance were observed in human amnion tissue after the labor-initiated spontaneous rupture of membranes

  3. endogenous LOX is overexpressed in clear cell renal cell carcinoma (show MOK Antibodies), is involved in a positive-regulative loop with HIF-1alpha (show HIF1A Antibodies), and has a major action on clear cell renal cell carcinoma (show MOK Antibodies) progression through cellular adhesion, migration, and collagen matrix stiffness increment

  4. colorectal carcinoma perilesional extracellular matrix has increased content of lysyl oxidase

  5. LOX affects the epithelial-mesenchymal transition of gastric cancer cells in hypoxic conditions.

  6. High expression of LOX is associated with nasopharyngeal carcinoma.

  7. Here we show that orthotopic implantation of rat prostate AT-1 tumour cells increased LOX and LOXLs mRNA expressions in the tumour and in the surrounding non-malignant prostate tissue

  8. Results show that LOX expression regulation by FoxF1 (show FOXF1 Antibodies) increases invasiveness of breast cancer cells.

  9. LOX gene expression was approximately 2.5-fold higher in fetal membranes from preterm prelabor rupture of membranes (pPROM (show SERPINH1 Antibodies)) compared to preterm and term birth.

  10. The data suggest a fibromodulin (show FMOD Antibodies)-modulated collagen cross-linking mechanism where fibromodulin (show FMOD Antibodies) binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites.

Pig (Porcine) Lysyl Oxidase (LOX) interaction partners

  1. Statins normalize vascular lysyl oxidase (LOX) down-regulation induced by proatherogenic risk factors.

Cow (Bovine) Lysyl Oxidase (LOX) interaction partners

  1. These results indicate that proLOX could be processed by two different mechanisms producing two forms of active LOX.

  2. Lysyl oxidase enhances elastin (show ELN Antibodies) synthesis and matrix formation by vascular smooth muscle cells

  3. Lysyl oxidase has a role in oxidizing basic fibroblast growth factor (show FGF2 Antibodies) and inactivating its mitogenic potential

  4. In cases of vascular calcification, the decreased expression of LOX may be partially responsible for decreased vascular elasticity and also for the decreased formation of new elastic fibers.

  5. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.

Mouse (Murine) Lysyl Oxidase (LOX) interaction partners

  1. LOX family members contribute significantly to the detrimental effects of cardiac remodelling, highlighting LOX inhibition as a potential therapeutic strategy for post-infarction recovery

  2. Findings suggest that the lysyl oxidase (LOX)-mediated organization of collagen fibers in the extracellular matrix is an important regulator of osteoblastogenesis.

  3. The data suggest a fibromodulin (show FMOD Antibodies)-modulated collagen cross-linking mechanism where fibromodulin (show FMOD Antibodies) binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites.

  4. Data suggest of pharmacologic targeting of lysyl oxidase (LOX) pathway to inhibit liver fibrosis and promote its resolution.

  5. Cu chaperone function of Atox1 (show ATOX1 Antibodies) mediated through Cu transporter ATP7A (show ATP7A Antibodies) is required for VEGF (show VEGFA Antibodies)-induced angiogenesis via activation of Cu enzyme lysyl oxidase.

  6. CTR1 (show SLC31A1 Antibodies), ATP7A (show ATP7A Antibodies), and lysyl oxidase were upregulated in the lung tissues and pulmonary arteries of mice with hypoxia-induced pulmonary hypertension and pulmonary arterial smooth muscle cells.

  7. Inhibition of tissue transglutaminase (show TGM2 Antibodies) resulted in a reduced rate of compaction compared to controls during early remodeling (up to 2 days). In contrast, inhibition of lysyl oxidase did not alter the early compaction.

  8. decreased expression of cross-linking enzymes (LOXs) and increased expression of ECM (show MMRN1 Antibodies)-degrading proteinases (MMP-1 (show MMP1 Antibodies), 2, 3) might be of great contribution to poor healing ability of PCL (show PKD2L1 Antibodies) ligament

  9. LOX is indispensable for the progression of BLM-induced experimental lung fibrosis by aggravating the inflammatory response and subsequent fibrosis process after lung injury.

  10. LOX and LOXL2 (show LOXL3 Antibodies) may play an important role in the pathogenesis of AMD (show AMD1 Antibodies). Targeting LOXL2 (show LOXL3 Antibodies) could have a broader efficacy than targeting LOX, by reducing angiogenesis and inflammation, as well as fibrosis.

LOX Antigen Profile

Protein Summary

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Lysyl Oxidase (LOX) Antibodies

  • lysyl oxidase (LOX) antibody
  • lysyl oxidase (lox) antibody
  • lysyl oxidase (Lox) antibody
  • lysyl oxidase (LOC100357045) antibody
  • AI893619 antibody
  • H-rev142 antibody
  • lox antibody
  • MGC146507 antibody
  • Rrg1 antibody
  • TSC-160 antibody
  • Xlox antibody
  • zgc:77447 antibody

Protein level used designations for anti-Lysyl Oxidase (LOX) Antibodies

lysyl oxidase , protein-lysine 6-oxidase-like , protein-lysine 6-oxidase , ras excision protein , ras recision gene (rrg) , Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)

GENE ID SPECIES
471614 Pan troglodytes
699997 Macaca mulatta
780067 Xenopus (Silurana) tropicalis
100189621 Oncorhynchus mykiss
100457685 Pongo abelii
404621 Danio rerio
734204 Xenopus laevis
4015 Homo sapiens
100525278 Sus scrofa
280841 Bos taurus
16948 Mus musculus
24914 Rattus norvegicus
396474 Gallus gallus
481478 Canis lupus familiaris
100720740 Cavia porcellus
100357045 Oryctolagus cuniculus
101112220 Ovis aries
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