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Lysyl Oxidase-Like 2 Proteins (LOXL2)

LOXL2 encodes a member of the lysyl oxidase gene family. Additionally we are shipping Lysyl Oxidase-Like 2 Antibodies (99) and Lysyl Oxidase-Like 2 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
LOXL2 4017 Q9Y4K0
LOXL2 94352 P58022
LOXL2 290350 B5DF27
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Top Lysyl Oxidase-Like 2 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$1,009.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$811.80
Details

LOXL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) , ,

Rat (Rattus)

More Proteins for Lysyl Oxidase-Like 2 (LOXL2) Interaction Partners

Fruit Fly (Drosophila melanogaster) Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. Dmloxl-1 and Dmloxl-2 are differentially expressed; active DmLOXL-1 influences gene expression and development

Human Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. Loss of tumor-suppressive miR29s enhanced cancer cell invasion in lung SCC (show CYP11A1 Proteins) through direct regulation of oncogenic LOXL2.

  2. LOXL2 promotes tumor progression.

  3. We identified LOXL2 to be associated with the outcome of colon cancer patients. Furthermore, it can be used to stratify patients at stages II and III for further therapeutic decisions.

  4. Data suggest that restoration of MIRN29 (microRNA 29) synthesis silences expression of LOXL2 (lysyl oxidase-like 2) and inhibits cell proliferation, migration, and invasiveness of renal cell carcinoma (show MOK Proteins) cells.

  5. Lysine oxidation of the transcription factor TAF10 (show TAF10 Proteins) by LOXL2 is a controlled protein modification and demonstrates a role for protein oxidation in regulating pluripotency genes.

  6. Results show that LOXL2 is highly expressed and involved in clear cell renal cell carcinoma (show MOK Proteins) progression by regulating the levels of integrins a5 and b1.

  7. identified novel alternative splicing isoform, LOXL2 Deltae13; data suggest it modulates effects of cancer cell migration and invasion through a different mechanism from full-length LOXL2 and may play an important role in tumor carcinogenesis and progression

  8. The structure and functions of human lysyl oxidase-like 2 (LOXL2) are reviewed. [review]

  9. LOXL2 is a direct repressor of NOTCH1 (show NOTCH1 Proteins).There is an exclusive expression pattern between LOXL2 and members of the canonical NOTCH1 (show NOTCH1 Proteins) pathway in human head and neck squamous cell carcinoma.

  10. Data indicate potential roles of LOXL2 (lysyl oxidase-like 2) splice variants with large scale data.

Mouse (Murine) Lysyl Oxidase-Like 2 (LOXL2) interaction partners

  1. LOX (show LOX Proteins) and LOXL2 (show LOXL3 Proteins) may play an important role in the pathogenesis of AMD (show AMD1 Proteins). Targeting LOXL2 (show LOXL3 Proteins) could have a broader efficacy than targeting LOX (show LOX Proteins), by reducing angiogenesis and inflammation, as well as fibrosis.

  2. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (show LOXL3 Proteins) and E47 (show TCF3 Proteins) in tumor growth and their requirement for lung metastasis.

  3. Findings reveal new insight into the mechanisms of fibroblast activation, a novel function of LOXL2 (show LOXL3 Proteins), and further highlight the importance of generating LOXL2 (show LOXL3 Proteins)-targeted therapies for the prevention of tumor progression and metastasis.

  4. The Snail1 (show SNAI1 Proteins) transcription factor represses mouse pericentromeric transcription, acting through the H3K4 deaminase LOXL2 (show LOXL3 Proteins).

  5. The enzymatic activity of lysyl oxidas-like-2 (LOXL2 (show LOXL3 Proteins)) is not required for LOXL2 (show LOXL3 Proteins)-induced inhibition of keratinocyte differentiation.

  6. This study provides the first evidence for the role of LOXL2 (show LOXL3 Proteins) in regulating angiogenesis through collagen IV (show COL4 Proteins) scaffolding.

  7. LOXL2 (show LOXL3 Proteins) promotes chondrocyte differentiation by mechanisms that are likely to include roles as both a regulator and an effector of chondrocyte differentiation

  8. The efficacy and safety of LOXL2 (show LOXL3 Proteins)-specific monoclonal antibody represents a new therapeutic approach with broad applicability in oncologic and fibrotic diseases.

  9. LoxL2 (show LOXL3 Proteins) is not expressed in MC3T3-E1 cells.

Lysyl Oxidase-Like 2 (LOXL2) Protein Profile

Protein Summary

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Gene names and symbols associated with Lysyl Oxidase-Like 2 Proteins (LOXL2)

  • lysyl oxidase-like 2 (lox2)
  • lysyl oxidase-like 2 (LOXL2)
  • lysyl oxidase-like 2 (loxl2)
  • lysyl oxidase-like 2 (Loxl2)
  • 1110004B06Rik protein
  • 4930526G11Rik protein
  • 9430067E15Rik protein
  • CG4402 protein
  • Dmel\\CG4402 protein
  • dmlox-2 protein
  • Dmloxl-2 protein
  • GB13360 protein
  • LOR2 protein
  • lox2-like protein
  • loxl-2 protein
  • LOXL2 protein
  • WS9-14 protein

Protein level used designations for Lysyl Oxidase-Like 2 Proteins (LOXL2)

CG4402-PA , lox2-PA , lysyl oxidase-like 2 , Lysyl oxidase-like protein 2 , lysyl oxidase homolog 2 , lysyl oxidase homolog 2-like , lysyl oxidase related 2 , lysyl oxidase-like protein 2 , lysyl oxidase-related protein 2 , lysyl oxidase-related protein WS9-14 , Lysyl oxidase homolog 2

GENE ID SPECIES
37485 Drosophila melanogaster
408544 Apis mellifera
585092 Strongylocentrotus purpuratus
100158339 Xenopus laevis
100216062 Xenopus (Silurana) tropicalis
100413360 Callithrix jacchus
464053 Pan troglodytes
710151 Macaca mulatta
100543026 Meleagris gallopavo
4017 Homo sapiens
419533 Gallus gallus
486118 Canis lupus familiaris
532684 Bos taurus
94352 Mus musculus
290350 Rattus norvegicus
100171427 Pongo abelii
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