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MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) ELISA Kits

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Additionally we are shipping MAD2L1 Antibodies (114) and MAD2L1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse MAD2L1 MAD2L1 56150 Q9Z1B5
Anti-Human MAD2L1 MAD2L1 4085 Q13257
Anti-Rat MAD2L1 MAD2L1 297176  
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More ELISA Kits for MAD2L1 Interaction Partners

Mouse (Murine) MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (show MXI1 ELISA Kits)

  2. study shows that Mad2 (show MXI1 ELISA Kits) is a novel substrate for CCP6 (show AGBL4 ELISA Kits) in megakaryocytes; Mad2 (show MXI1 ELISA Kits) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis

  3. Exacerbating chromosome missegregation in CENP-E (show CENPE ELISA Kits)+/- mice by reducing levels of another mitotic checkpoint component (show BUB3 ELISA Kits), Mad2 (show MXI1 ELISA Kits), results in elevated cell death and decreased tumor formation compared with reduction of either protein alone.

  4. Mad2 (show MXI1 ELISA Kits) is also repressed by p53 (show TP53 ELISA Kits) and its upregulation is required for chromosome instability in a p53 (show TP53 ELISA Kits) mutant tumor model

  5. Data show that Mad2 (show MXI1 ELISA Kits) haploinsufficiency is protective in the presence of a cycle-specific DNA synthesis agent in vivo, and Ape1/Ref-1 (show APEX1 ELISA Kits) inhibitor in vitro.

  6. Pcid2 (show PCID2 ELISA Kits) is essential for B cell survival through the regulation of MAD2 (show MXI1 ELISA Kits) expression during B cell differentiation

  7. tumours that experience transient Mad2 (show MXI1 ELISA Kits) overexpression and consequent chromosome instability recur at markedly elevated rates

  8. a functional Mad2 (show MXI1 ELISA Kits)-dependent spindle checkpoint exists during the first meiotic division in mammalian oocytes

  9. Data show that the loss of Trrap (show TRRAP ELISA Kits) leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap (show TRRAP ELISA Kits)-mediated transcription of the mitotic checkpoint (show BUB3 ELISA Kits) proteins Mad1 (show MXD1 ELISA Kits) and Mad2 (show MXI1 ELISA Kits).

  10. that Brca1 (show BRCA1 ELISA Kits)(Delta11/Delta11) cells displayed decreased expression of a number of genes that are involved in the spindle checkpoint, including Mad2 (show MXI1 ELISA Kits)

Human MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) interaction partners

  1. Studied the folding/unfolding process of the open and closed conformers of human Mad2.

  2. MAD1L1 (show MAD1L1 ELISA Kits) Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer

  3. p31comet-induced cell death is mediated by interactions with Mad2

  4. MAD2L1 and BUB1 (show BUB1 ELISA Kits) may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

  5. We also show that replication perturbations result in relocalization of MAD1 (show MXD1 ELISA Kits)/MAD2 in human cells, suggesting that the role of SAC (show ADCY10 ELISA Kits) in DNA repair is conserved.

  6. Data indicate the structure of the intermediate conformer of the multistate checkpoint protein mitotic arrest deficient 2 (Mad2) protein.

  7. WT1 (show WT1 ELISA Kits) has a role in interacting MAD2 and regulating mitotic checkpoint (show BUB3 ELISA Kits) function

  8. In conclusion, the results presented here suggest that Mad2 and BubR1 (show BUB1B ELISA Kits) could be used as prognostic markers of tumor progression and new pharmacological targets in the treatment for gastric cancer .

  9. Co-depletion of MAD2 and BUBR1 (show BUB1B ELISA Kits) causes cell cycle arrest and cell death in addition to aneuploidy.

  10. hMAD2 also binds to the hREV7 (show MAD2L2 ELISA Kits)-binding sequence in hREV3, whereas hMAD2 does not bind to a similar sequence in ADAM9 (show ADAM9 ELISA Kits) or ELK-1 (show ELK1 ELISA Kits) and hREV7 (show MAD2L2 ELISA Kits) does not bind to the hMAD2-binding sequence in hMAD1 or hCDC20.

MAD2L1 Antigen Profile

Antigen Summary

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Gene names and symbols associated with MAD2L1

  • MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1) antibody
  • MAD2 mitotic arrest deficient-like 1 (yeast) (mad2l1) antibody
  • MAD2 mitotic arrest deficient-like 1 (mad2l1) antibody
  • MAD2 mitotic arrest deficient-like 1 (MAD2L1) antibody
  • MAD2 mitotic arrest deficient-like 1 (yeast) (LOC100218172) antibody
  • MAD2 mitotic arrest deficient-like 1 (Mad2l1) antibody
  • MAD2 mitotic arrest deficient-like 1 (yeast) (Mad2l1) antibody
  • AA673185 antibody
  • cb408 antibody
  • HSMAD2 antibody
  • MAD2 antibody
  • MAD2L1 antibody
  • XMad2 antibody
  • zgc:112133 antibody

Protein level used designations for MAD2L1

MAD2-like 1 , mitotic spindle assembly checkpoint protein MAD2A , spindle assembly checkpoint protein Mad2 , MAD2 mitotic arrest deficient-like 1 (yeast) , MAD2 mitotic arrest deficient-like 1 , MAD2 (mitotic arrest deficient, homolog)-like 1 , MAD2-like protein 1 , mitotic arrest deficient 2-like protein 1 , MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 , mitotic arrest deficient, yeast, homolog-like 1

GENE ID SPECIES
461661 Pan troglodytes
550434 Danio rerio
708574 Macaca mulatta
787996 Bos taurus
100125170 Xenopus (Silurana) tropicalis
100137358 Papio anubis
100218172 Taeniopygia guttata
56150 Mus musculus
380433 Xenopus laevis
4085 Homo sapiens
422675 Gallus gallus
476070 Canis lupus familiaris
337870 Bos taurus
297176 Rattus norvegicus
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