MAD2L1 Binding Protein (MAD2L1BP) ELISA Kits

The protein encoded by MAD2L1BP was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). Additionally we are shipping MAD2L1BP Antibodies (67) and MAD2L1BP Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat MAD2L1BP MAD2L1BP 316237  
Anti-Human MAD2L1BP MAD2L1BP 9587 Q15013
Anti-Mouse MAD2L1BP MAD2L1BP 66591 Q9DCX1
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More ELISA Kits for MAD2L1BP Interaction Partners

Human MAD2L1 Binding Protein (MAD2L1BP) interaction partners

  1. Thes authors show that p31 (show ATP6V1E1 ELISA Kits)(comet) binding to the TRIP13 (show TRIP13 ELISA Kits) N-terminal domain positions the disordered MAD2 (show MAD2L1 ELISA Kits) N-terminus for engagement by the TRIP13 (show TRIP13 ELISA Kits) "pore loops", which then unfold MAD2 (show MAD2L1 ELISA Kits) in the presence of ATP.

  2. p31comet-induced cell death is mediated by interactions with Mad2 (show MAD2L1 ELISA Kits)

  3. the oligomeric form of TRIP13 binds both p31(comet) and MCC

  4. joint action of TRIP13 (show TRIP13 ELISA Kits) and p31 (show ATP6V1E1 ELISA Kits)(comet) also promotes the release of Mad2 (show MAD2L1 ELISA Kits) from MCC, participates in the complete disassembly of MCC and abrogates checkpoint inhibition of APC (show APC ELISA Kits)/C

  5. Altered p31 (show ATP6V1E1 ELISA Kits)(Comet):Mad2 (show MAD2L1 ELISA Kits) expression ratios may provide new insight into altered spindle assembly checkpoint function and the generation of chromosomal instability in tumors.

  6. attenuating the affinity of p31 (show ATP6V1E1 ELISA Kits)(Comet) for Mad2 (show MAD2L1 ELISA Kits) by phosphorylation promotes SAC (show ADCY10 ELISA Kits) activity in mitosis. Specifically, phosphorylation of Ser (show SIGLEC1 ELISA Kits)-102 weakens p31 (show ATP6V1E1 ELISA Kits)(Comet)-Mad2 (show MAD2L1 ELISA Kits) binding and enhances p31 (show ATP6V1E1 ELISA Kits)(Comet)-mediated bypass of the SAC (show ADCY10 ELISA Kits).

  7. study found p31 (show ATP6V1E1 ELISA Kits)(comet) traffics on and off kinetochores and also present in the cytosol; Cells depleted of p31 (show ATP6V1E1 ELISA Kits)(comet) arrest in metaphase with mature bipolar kinetochore-microtubule attachments; propose that p31 (show ATP6V1E1 ELISA Kits)(comet) is an essential component of machinery that silences the checkpoint during each cell cycle

  8. the importance of p31 (show ATP6V1E1 ELISA Kits)(comet) in checkpoint silencing and its potential as a target for antimitotic therapies.

  9. The binding of p31 (show ATP6V1E1 ELISA Kits)(comet) to Mad2 (show MAD2L1 ELISA Kits) in mitotic checkpoint (show BUB3 ELISA Kits) complex may trigger a conformational change in Cdc20 (show CDC20 ELISA Kits) that facilitates its phosphorylation by Cdk (show CDK4 ELISA Kits), and that the latter process may promote its dissociation from BubR1 (show BUB1B ELISA Kits).

  10. both p31 (show ATP6V1E1 ELISA Kits)(comet) and ubiquitination of Cdc20 (show CDC20 ELISA Kits) are critical mechanisms of checkpoint inactivation. They act redundantly to promote Mad2 (show MAD2L1 ELISA Kits) dissociation from Cdc20 (show CDC20 ELISA Kits)

Mouse (Murine) MAD2L1 Binding Protein (MAD2L1BP) interaction partners

  1. p31comet-induced cell death is mediated by interactions with Mad2 (show MXI1 ELISA Kits)

MAD2L1BP Antigen Profile

Antigen Summary

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with MAD2L1BP

  • MAD2L1 binding protein (Mad2l1bp) antibody
  • MAD2L1 binding protein (MAD2L1BP) antibody
  • 0610009D16Rik antibody
  • 2510031P20Rik antibody
  • AU018945 antibody
  • AW550977 antibody
  • C76045 antibody
  • CMT2 antibody
  • CMT2A antibody
  • CMT2B antibody
  • MAD2L1BP antibody
  • Mad2lbp antibody
  • mKIAA0110 antibody
  • RP1-261G23.6 antibody

Protein level used designations for MAD2L1BP

MAD2L1-binding protein , MAD2L1 binding protein , caught by MAD2 protein

316237 Rattus norvegicus
421448 Gallus gallus
462721 Pan troglodytes
474916 Canis lupus familiaris
615542 Bos taurus
701099 Macaca mulatta
9587 Homo sapiens
66591 Mus musculus
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