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MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) ELISA Kits

MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases. Additionally we are shipping MAP/microtubule Affinity-Regulating Kinase 2 Antibodies (89) and MAP/microtubule Affinity-Regulating Kinase 2 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MARK2 MARK2 2011 Q7KZI7
Anti-Mouse MARK2 MARK2 13728 Q05512
Anti-Rat MARK2 MARK2 60328 O08679
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More ELISA Kits for MAP/microtubule Affinity-Regulating Kinase 2 Interaction Partners

Human MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) interaction partners

  1. MARK2 plays a role in promoting malignant phenotypes of lung cancer.

  2. Phosphorylation of RNF41 (show RNF41 ELISA Kits) by Par-1b regulates basolateral membrane targeting of laminin-111 receptors.

  3. induces asymmetric inheritance of plasma membrane domains via LGN (show GPSM2 ELISA Kits)-dependent mitotic spindle orientation in proliferating hepatocytes

  4. Perturbation of PAR1b and SHP2 (show PTPN11 ELISA Kits) by CagA (show S100A8 ELISA Kits) underlies the oncogenic potential of CagA (show S100A8 ELISA Kits).

  5. The MARK2 binds to the N-terminal tail of Tau and selectively phosphorylates three major and five minor serine residues in the repeat domain and C-terminal tail.

  6. Hepatocyte Par1b defines lumen position in concert with the position of the astral microtubule anchoring complex LGN (show GPSM2 ELISA Kits)-NuMA (show NUMA1 ELISA Kits) to yield the distinct epithelial division phenotypes.

  7. automated image analysis of MT assembly dynamics identified MARK2 as a target regulated downstream of Rac1 that promotes oriented MT growth in the leading edge to mediate directed cell migration.

  8. The scaffolding adaptor GAB1 interacts with two polarity proteins, PAR1 and PAR3 (show F2RL2 ELISA Kits).

  9. The results identify MARK2 as an upstream regulator of PINK1 and DeltaN-PINK1 and provide insights into the regulation of mitochondrial trafficking in neurons and neurodegeneration in PD.

  10. Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1 (show ARHGEF2 ELISA Kits)) to regulate RhoA (show RHOA ELISA Kits)-dependent actin cytoskeletal reorganization.

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) interaction partners

  1. a model whereby MARK2 negatively regulates insulin (show INS ELISA Kits) sensitivity in peripheral tissue through inhibition of KSR1 (show KSR1 ELISA Kits)

  2. ROCK1 (show ROCK1 ELISA Kits)/PAR-1b-dependent regulation of basement membrane placement is required for the coordination of tissue polarity and the elaboration of tissue structure in the developing submandibular salivary gland.

  3. PAR1b plays a novel role in the maintenance of mature dendritic spine morphology by regulating microtubule growth and the accumulation of p140Cap (show SRCIN1 ELISA Kits) in dendritic spines.

  4. Par-1b is a regulator of glucose metabolism and adiposity in the whole animal

  5. Interaction of MARK2 with CaMKI (show CAMK1 ELISA Kits) results in a novel, calcium-dependent pathway that plays an important role in neuronal differentiation.

  6. Akt (show AKT1 ELISA Kits) enhances the activity of PAR1 (show F2R ELISA Kits) to promote tau hyperphosphorylation at S262/S356, a tau species that is not recognized by the CHIP/Hsp90 (show HSP90 ELISA Kits) complex

  7. Coreduction of MARK2 and DCX (show DCX ELISA Kits) resulted in a partial restoration of the normal neuronal migration phenotype in vivo. The kinetic behavior of the centrosomes reflected the different molecular mechanisms activated when either protein was reduced.

MAP/microtubule Affinity-Regulating Kinase 2 (MARK2) Antigen Profile

Antigen Summary

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MARK2

  • MAP/microtubule affinity-regulating kinase 2 (MARK2) antibody
  • MAP/microtubule affinity-regulating kinase 2 (Mark2) antibody
  • AU024026 antibody
  • Emk antibody
  • EMK-1 antibody
  • EMK1 antibody
  • mKIAA4207 antibody
  • Par-1 antibody
  • Par-1b antibody
  • Par1b antibody

Protein level used designations for MARK2

ELKL motif kinase 1 , PAR1 homolog b , Ser/Thr protein kinase PAR-1B , serine/threonine protein kinase EMK , serine/threonine-protein kinase MARK2 , EMK-1 , EMK1 , serine/threonine kinase

GENE ID SPECIES
100049882 Equus caballus
2011 Homo sapiens
13728 Mus musculus
483769 Canis lupus familiaris
535197 Bos taurus
60328 Rattus norvegicus
100737238 Sus scrofa
100731733 Cavia porcellus
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