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The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. Additionally we are shipping MLF1IP Kits (17) and MLF1IP Proteins (7) and many more products for this protein.
Showing 10 out of 77 products:
Chimpanzee Polyclonal MLF1IP Primary Antibody for EIA, WB - ABIN401440
Pan, Zhang, Wang, Deng, Zhou, Gao: Identification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus. in Journal of virology 2003
Show all 4 references for ABIN401440
Cow (Bovine) Polyclonal MLF1IP Primary Antibody for EIA, WB - ABIN401336
Hanissian, Teng, Akbar, Janjetovic, Zhou, Duntsch, Robertson: Regulation of myeloid leukemia factor-1 interacting protein (MLF1IP) expression in glioblastoma. in Brain research 2005
Show all 4 references for ABIN401336
Chimpanzee Polyclonal MLF1IP Primary Antibody for EIA, WB - ABIN401442
Hanissian, Akbar, Teng, Janjetovic, Hoffmann, Hitzler, Iscove, Hamre, Du, Tong, Mukatira, Robertson, Morris: cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP. in Oncogene 2004
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MLF1IP significantly promotes prostate cancer cell proliferation and colony formation and significantly inhibits apoptosis without affecting cell cycle phase arrest in prostate cancer cell lines
Plk1 (show PLK1 Antibodies) regulates the timing of the delocalization and ultimate destruction of the PBIP1.CENP-Q (show CENPQ Antibodies) complex.
Data propose that CENP-P (show CENPP Antibodies)/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.
Mammalian polo-like kinase 1 (show PLK1 Antibodies)-dependent regulation of the PBIP1-CENP-Q (show CENPQ Antibodies) complex at kinetochores.
CENP-U is a novel microtubule binding protein and plays an important role in kinetochore-microtubule attachment through its interaction with Hec1
a possible role for MLF1IP deregulation in the genesis of erythroleukemias
MLF1IP was found in glioblastomas where it was co-localized with MLF1 (show MLF1 Antibodies) and nestin (show NES Antibodies). Moreover, it was elevated in the contralateral brain where no tumor cells occurred, suggesting a role in glioma pathogenesis and potentially in other types of malignancies.
Plk1 (show PLK1 Antibodies) self-regulates the Plk1 (show PLK1 Antibodies)-PBIP1 interaction to timely localize to the kinetochores and promote proper chromosome segregation.
Deletion mutants of MLF1IP revealed that the N-terminal bipartite nuclear localization signal (NLS (show ALDH1A2 Antibodies)) was responsible for nucleolar targeting.
MLF1 (show MLF1 Antibodies)-IP expression at about 50% of its normal level is sufficient to sustain mice life and the development of their immune system without apparent abnormalities.
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006
MLF1 interacting protein
, centromere protein U-like
, KSHV latent nuclear antigen interacting protein 1
, KSHV latent nuclear antigen-interacting protein 1
, MLF1-interacting protein
, centromere protein U
, centromere protein of 50 kDa
, interphase centromere complex protein 24
, polo-box-interacting protein 1
, myeloid leukemia factor 1 interacting protein
, centromere protein p50