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MLF1 Interacting Protein Proteins (MLF1IP)

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. Additionally we are shipping MLF1IP Antibodies (74) and MLF1IP Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MLF1IP 79682 Q71F23
MLF1IP 306464 Q4V8G7
MLF1IP 71876 Q8C4M7
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Top MLF1IP Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,937.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,131.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,138.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details

MLF1IP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for MLF1 Interacting Protein (MLF1IP) Interaction Partners

Human MLF1 Interacting Protein (MLF1IP) interaction partners

  1. MLF1IP significantly promotes prostate cancer cell proliferation and colony formation and significantly inhibits apoptosis without affecting cell cycle phase arrest in prostate cancer cell lines

  2. Plk1 regulates the timing of the delocalization and ultimate destruction of the PBIP1.CENP-Q (show CENPQ Proteins) complex.

  3. Data propose that CENP-P (show CENPP Proteins)/O/R/Q/U self-assembles on kinetochores with varying stoichiometry and undergoes a pre-mitotic maturation step that could be important for kinetochores switching into the correct conformation for microtubule-attachment.

  4. Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q (show CENPQ Proteins) complex at kinetochores.

  5. CENP-U is a novel microtubule binding protein and plays an important role in kinetochore-microtubule attachment through its interaction with Hec1

  6. a possible role for MLF1IP deregulation in the genesis of erythroleukemias

  7. MLF1IP was found in glioblastomas where it was co-localized with MLF1 (show MLF1 Proteins) and nestin (show NES Proteins). Moreover, it was elevated in the contralateral brain where no tumor cells occurred, suggesting a role in glioma pathogenesis and potentially in other types of malignancies.

  8. Plk1 self-regulates the Plk1-PBIP1 interaction to timely localize to the kinetochores and promote proper chromosome segregation.

  9. Deletion mutants of MLF1IP revealed that the N-terminal bipartite nuclear localization signal (NLS (show ALDH1A2 Proteins)) was responsible for nucleolar targeting.

Mouse (Murine) MLF1 Interacting Protein (MLF1IP) interaction partners

  1. MLF1 (show MLF1 Proteins)-IP expression at about 50% of its normal level is sufficient to sustain mice life and the development of their immune system without apparent abnormalities.

MLF1IP Protein Profile

Protein Summary

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006

Gene names and symbols associated with MLF1IP

  • MLF1 interacting protein (mlf1ip)
  • MLF1 interacting protein (MLF1IP)
  • MLF1 interacting protein (Mlf1ip)
  • myeloid leukemia factor 1 interacting protein (Mlf1ip)
  • 1700029A22Rik protein
  • CENP-50 protein
  • CENP-U protein
  • CENP50 protein
  • CENPU protein
  • CENPU50 protein
  • KLIP1 protein
  • MGC147270 protein
  • PBIP1 protein

Protein level used designations for MLF1IP

MLF1 interacting protein , CENP-U , centromere protein U-like , KSHV latent nuclear antigen interacting protein 1 , KSHV latent nuclear antigen-interacting protein 1 , MLF1-interacting protein , centromere protein U , centromere protein of 50 kDa , interphase centromere complex protein 24 , polo-box-interacting protein 1 , myeloid leukemia factor 1 interacting protein , centromere protein p50

GENE ID SPECIES
780000 Xenopus (Silurana) tropicalis
100499428 Meleagris gallopavo
100435854 Pongo abelii
100586173 Nomascus leucogenys
79682 Homo sapiens
607799 Canis lupus familiaris
617866 Bos taurus
306464 Rattus norvegicus
461630 Pan troglodytes
422548 Gallus gallus
71876 Mus musculus
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