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anti-MLX Interacting Protein-Like (MLXIPL) Antibodies

MLXIPL encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. Additionally we are shipping MLXIPL Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MLXIPL 51085 Q9NP71
MLXIPL 58805 Q99MZ3
MLXIPL 171078 Q8VIP2
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Top anti-MLXIPL Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with MLXIPL Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of MLXIPL Antibody (C-term) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the MLXIPL antibody detected the MLXIPL protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, IHC (p), IP, IHC, WB Detection of ChREBP in 20 ug of human hepatocyte lysate using ABIN152902. 5-10 second film exposure. Immunofluorescent staining of a human hepatocyte using ABIN152902.  Overlay staining of ChREBP (rhodamine red) and DAPI nuclear staining (blue). 0.025 mL Log in to see 5 to 7 Days
$203.44
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-MLXIPL Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ICC, ELISA, WB 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (p), WB MLXIPL Antibody (C-term) (ABIN656493) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IF, WB Immunofluorescent staining of a human hepatocyte using ABIN152903.  Overlay staining of ChREBP (rhodamine red) and DAPI nuclear staining (blue). 0.1 mL Log in to see 5 to 7 Days
$391.13
Details
Mouse Rabbit Un-conjugated ChIP, ICC, IF, IHC (p), IP, WB 100 μL Log in to see 5 to 6 Days
$506.80
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

MLXIPL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MLXIPL Antibodies

  1. Human Polyclonal MLXIPL Primary Antibody for EIA, IHC (p) - ABIN953464 : Johansen, Wang, Lanktree, Cao, McIntyre, Ban, Martins, Kennedy, Hassell, Visser, Schwartz, Voight, Elosua, Salomaa, ODonnell, Dallinga-Thie, Anand, Yusuf, Huff, Kathiresan, Hegele: Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. in Nature genetics 2010 (PubMed)
    Show all 4 references for ABIN953464

  2. Human Monoclonal MLXIPL Primary Antibody for ICC, ELISA - ABIN1724913 : Hurtado del Pozo, Vesperinas-García, Rubio, Corripio-Sánchez, Torres-García, Obregon, Calvo: ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 2 references for ABIN1724913

  3. Cow (Bovine) Polyclonal MLXIPL Primary Antibody for IHC, WB - ABIN2778415 : Cairo, Merla, Urbinati, Ballabio, Reymond: WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network. in Human molecular genetics 2001 (PubMed)

More Antibodies against MLXIPL Interaction Partners

Human MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. High glucose-mediated induction of PDGF-C (show PDGFC Antibodies) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. Evaluation of the conservation of ChREBP and MondoA (show MLXIP Antibodies) sequences demonstrate that MondoA (show MLXIP Antibodies) is better conserved and potentially mediates more ancient function in glucose metabolism.

  3. Metformin down-regulates high-glucose-induced TXNIP (show TXNIP Antibodies) transcription by inactivating ChREBP and FOXO1 (show FOXO1 Antibodies) in endothelial cells, partially through AMP-activated protein kinase (show PRKAA2 Antibodies) activation

  4. Polymorphisms in lipid level modifier MLXIPL, GCKR (show GCKR Antibodies), GALNT2 (show GALNT2 Antibodies), CILP2 (show Cilp2 Antibodies), ANGPTL3 (show ANGPTL3 Antibodies) and TRIB1 (show TRIB1 Antibodies) genes are highly associated with plasma lipid level changes.

  5. Single-nucleotide polymorphisms alleles near MLXIPL that were associated with higher coffee consumption.

  6. A major function of Mio in mitosis is to regulate the activation/deactivation of Plk1 (show PLK1 Antibodies) and Aurora A (show AURKA Antibodies).

  7. the single nucleotide polymorphism of MLXIPL is significantly associated with Non-alcoholic Fatty Liver Disease.

  8. results demonstrate that AGEs-RAGE (show AGER Antibodies) signaling enhances cancer cell proliferation in which AGEs-mediated ChREBP induction plays an important role.

  9. Significant linkage disequilibria were noted among ZNF259 (show znf259 Antibodies), BUD13 and MLXIPL SNPs and serum lipid levels.

  10. demonstrates that Chrebp interacts with AR and regulates its transcriptional activity

Mouse (Murine) MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. High glucose-mediated induction of PDGF-C (show PDGFC Antibodies) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. Adipose tissue mTORC2 (show CRTC2 Antibodies) regulates via Rictor (show RICTOR Antibodies) ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.

  3. Targeted deletion of ChREBP in bone marrow cells resulted in accelerated atherosclerosis progression in Ldlr (show LDLR Antibodies)-/- mice with increased monocytosis, lesional macrophage accumulation, and plaque necrosis.

  4. Evaluation of the conservation of ChREBP and MondoA (show MLXIP Antibodies) sequences demonstrate that MondoA (show MLXIP Antibodies) is better conserved and potentially mediates more ancient function in glucose metabolism.

  5. Data show that carbohydrate-response element-binding protein (ChREBP) activation induces peroxisome proliferator-activated receptor (PPARgamma (show PPARG Antibodies)) activity and ChREBP inhibition impairs differentiation.

  6. hyperinsulinemia may cause glycolipid metabolic disorders by up-regulating the expression of ChREBP

  7. LXRs act as nutrient and glucose metabolic sensors upstream of ChREBP

  8. The effects of ethanol on AMPK (show PRKAA1 Antibodies) and PP2A (show PPP2R2B Antibodies) may result in activation of ChREBP, providing another potential mechanism for ethanol-induced hepatic steatosis.

  9. Depletion of ChREBP decreased glucose-stimulated proliferation in beta-cells isolated from ChREBP(-/-) mice, in INS-1-derived 832/13 cells, and in primary rat and human beta-cells

  10. Data indicate that ChREBP is a key transcription factor that mediates many of the hyperglycaemia-induced activations in a gene expression programme that underlies beta cell glucotoxicity at the molecular, cellular and whole animal levels.

MLXIPL Antigen Profile

Protein Summary

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Gene names and symbols associated with MLXIPL

  • MLX interacting protein-like (MLXIPL) antibody
  • MLX interacting protein-like (Mlxipl) antibody
  • bHLHd14 antibody
  • CHREBP antibody
  • MIO antibody
  • MLXIPL antibody
  • MONDOB antibody
  • Wbscr14 antibody
  • WS-bHLH antibody

Protein level used designations for MLXIPL

MLX interacting protein-like , carbohydrate response element binding protein variant 1 , carbohydrate response element binding protein variant 2 , Williams-Beuren syndrome chromosomal region 14 protein homolog , carbohydrate responsive element binding protein , williams-Beuren syndrome chromosomal region 14 protein homolog , MLX-interacting protein-like , Mlx interactor , WS basic-helix-loop-helix leucine zipper protein , Williams Beuren syndrome chromosome region 14 , Williams-Beuren syndrome chromosome region 14 protein 1 , Williams-Beuren syndrome chromosome region 14 protein 2 , carbohydrate response element binding protein , carbohydrate-responsive element-binding protein , class D basic helix-loop-helix protein 14 , williams-Beuren syndrome chromosomal region 14 protein , MLX interacting protein-like beta , MLX interactor , Williams-Beuren syndrome chromosome region 14 homolog , putative hepatic transcription factor , WBSCR14 protein-like , Williams-Beuren syndrome chromosomal region 14 protein

GENE ID SPECIES
425603 Gallus gallus
489807 Canis lupus familiaris
100059888 Equus caballus
100170769 Sus scrofa
100438130 Pongo abelii
51085 Homo sapiens
58805 Mus musculus
788534 Bos taurus
171078 Rattus norvegicus
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