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MLX Interacting Protein-Like Proteins (MLXIPL)

MLXIPL encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. Additionally we are shipping MLXIPL Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MLXIPL 51085 Q9NP71
MLXIPL 58805 Q99MZ3
Rat MLXIPL MLXIPL 171078 Q8VIP2
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Top MLXIPL Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

MLXIPL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for MLX Interacting Protein-Like (MLXIPL) Interaction Partners

Human MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. High glucose-mediated induction of PDGF-C (show PDGFC Proteins) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. Evaluation of the conservation of ChREBP and MondoA (show MLXIP Proteins) sequences demonstrate that MondoA (show MLXIP Proteins) is better conserved and potentially mediates more ancient function in glucose metabolism.

  3. Metformin down-regulates high-glucose-induced TXNIP (show TXNIP Proteins) transcription by inactivating ChREBP and FOXO1 (show FOXO1 Proteins) in endothelial cells, partially through AMP-activated protein kinase (show PRKAA2 Proteins) activation

  4. Polymorphisms in lipid level modifier MLXIPL, GCKR (show GCKR Proteins), GALNT2 (show GALNT2 Proteins), CILP2, ANGPTL3 (show ANGPTL3 Proteins) and TRIB1 (show TRIB1 Proteins) genes are highly associated with plasma lipid level changes.

  5. Single-nucleotide polymorphisms alleles near MLXIPL that were associated with higher coffee consumption.

  6. A major function of Mio in mitosis is to regulate the activation/deactivation of Plk1 and Aurora A (show AURKA Proteins).

  7. the single nucleotide polymorphism of MLXIPL is significantly associated with Non-alcoholic Fatty Liver Disease.

  8. results demonstrate that AGEs-RAGE (show AGER Proteins) signaling enhances cancer cell proliferation in which AGEs-mediated ChREBP induction plays an important role.

  9. Significant linkage disequilibria were noted among ZNF259 (show znf259 Proteins), BUD13 and MLXIPL SNPs and serum lipid levels.

  10. demonstrates that Chrebp interacts with AR and regulates its transcriptional activity

Mouse (Murine) MLX Interacting Protein-Like (MLXIPL) interaction partners

  1. High glucose-mediated induction of PDGF-C (show PDGFC Proteins) via ChREBP in mesangial cells contributes to the development of glomerular mesangial expansion in diabetes.

  2. Adipose tissue mTORC2 (show CRTC2 Proteins) regulates via Rictor ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.

  3. Targeted deletion of ChREBP in bone marrow cells resulted in accelerated atherosclerosis progression in Ldlr (show LDLR Proteins)-/- mice with increased monocytosis, lesional macrophage accumulation, and plaque necrosis.

  4. Evaluation of the conservation of ChREBP and MondoA (show MLXIP Proteins) sequences demonstrate that MondoA (show MLXIP Proteins) is better conserved and potentially mediates more ancient function in glucose metabolism.

  5. Data show that carbohydrate-response element-binding protein (ChREBP) activation induces peroxisome proliferator-activated receptor (PPARgamma (show PPARG Proteins)) activity and ChREBP inhibition impairs differentiation.

  6. hyperinsulinemia may cause glycolipid metabolic disorders by up-regulating the expression of ChREBP

  7. LXRs act as nutrient and glucose metabolic sensors upstream of ChREBP

  8. The effects of ethanol on AMPK (show PRKAA1 Proteins) and PP2A (show PPP2R2B Proteins) may result in activation of ChREBP, providing another potential mechanism for ethanol-induced hepatic steatosis.

  9. Depletion of ChREBP decreased glucose-stimulated proliferation in beta-cells isolated from ChREBP(-/-) mice, in INS-1-derived 832/13 cells, and in primary rat and human beta-cells

  10. Data indicate that ChREBP is a key transcription factor that mediates many of the hyperglycaemia-induced activations in a gene expression programme that underlies beta cell glucotoxicity at the molecular, cellular and whole animal levels.

MLXIPL Protein Profile

Protein Summary

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Gene names and symbols associated with MLXIPL

  • MLX interacting protein-like (MLXIPL)
  • MLX interacting protein-like (Mlxipl)
  • bHLHd14 protein
  • CHREBP protein
  • MIO protein
  • MLXIPL protein
  • MONDOB protein
  • Wbscr14 protein
  • WS-bHLH protein

Protein level used designations for MLXIPL

MLX interacting protein-like , carbohydrate response element binding protein variant 1 , carbohydrate response element binding protein variant 2 , Williams-Beuren syndrome chromosomal region 14 protein homolog , carbohydrate responsive element binding protein , williams-Beuren syndrome chromosomal region 14 protein homolog , MLX-interacting protein-like , Mlx interactor , WS basic-helix-loop-helix leucine zipper protein , Williams Beuren syndrome chromosome region 14 , Williams-Beuren syndrome chromosome region 14 protein 1 , Williams-Beuren syndrome chromosome region 14 protein 2 , carbohydrate response element binding protein , carbohydrate-responsive element-binding protein , class D basic helix-loop-helix protein 14 , williams-Beuren syndrome chromosomal region 14 protein , MLX interacting protein-like beta , MLX interactor , Williams-Beuren syndrome chromosome region 14 homolog , putative hepatic transcription factor , WBSCR14 protein-like , Williams-Beuren syndrome chromosomal region 14 protein

GENE ID SPECIES
425603 Gallus gallus
489807 Canis lupus familiaris
100059888 Equus caballus
100170769 Sus scrofa
100438130 Pongo abelii
51085 Homo sapiens
58805 Mus musculus
788534 Bos taurus
171078 Rattus norvegicus
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