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MMS19 Nucleotide Excision Repair Homolog (S. Cerevisiae) Proteins (MMS19)

May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER- transcription factor TFIIH. Additionally we are shipping MMS19 Antibodies (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MMS19 111647  
MMS19 64210 Q96T76
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Top MMS19 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

MMS19 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for MMS19 Nucleotide Excision Repair Homolog (S. Cerevisiae) (MMS19) Interaction Partners

Mouse (Murine) MMS19 Nucleotide Excision Repair Homolog (S. Cerevisiae) (MMS19) interaction partners

  1. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

  2. in the absence of MMS19, a failure to transfer Fe-S clusters to target proteins (show NCOA5 Proteins)is associated wi (show CIAO1 Proteins)th Fe- (show NARFL Proteins)S protein (show FAM96B Proteins)instability and preimplantation death of mice in which Mms19 has been knocked out; propose that MMS19 functions as a platform to facilitate Fe-S cluster transfer to proteins critical for DNA replication and repair

  3. Cloning of the mouse MMS19 genes and functional complementation in Saccharomyces cerevisiae

  4. Mms19 has distinct and separable functions in nucleotide excision repair and cell growth

Human MMS19 Nucleotide Excision Repair Homolog (S. Cerevisiae) (MMS19) interaction partners

  1. Suggest that MMS19 may be a potential new predictor of metastasis and chemoradiotherapy response in esophageal squamous cell carcinoma.

  2. MMS19L polymorphisms are associated with response to chemotherapy in osteosarcoma.

  3. Single nucleotide polymorphisms in the MMS19L gene is associated with bone malignant tumors.

  4. Polymorphisms in ERCC1 (show ERCC1 Proteins), codon-118 and MMS19 genes are not associated with clinical response to platinum or survival.

  5. MMS19 interacts with target proteins. MIP18 (show FAM96B Proteins) has a role to bridge MMS19 and CIAO1 (show CIAO1 Proteins). CIAO1 (show CIAO1 Proteins) also binds IOP1 (show NARFL Proteins).

  6. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

  7. study demonstrates MMS19 forms a complex with the cytoplasmic Fe-S assembly (CIA (show ASF1A Proteins)) proteins CIAO1 (show CIAO1 Proteins), IOP1 (show NARFL Proteins) and MIP18 (show FAM96B Proteins); cytoplasmic MMS19 also binds to multiple nuclear Fe-S proteins involved in DNA metabolism; propose that MMS19 functions as a platform to facilitate Fe-S cluster transfer to proteins critical for DNA replication and repair

  8. identified MMS19 as a member of the cytosolic iron-sulfur protein assembly (CIA (show ASF1A Proteins)) machinery; MMS19 functions as part of the CIA (show ASF1A Proteins) targeting complex that interacts with and facilitates iron-sulfur cluster insertion into apoproteins involved in methionine biosynthesis, DNA replication, DNA repair, and telomere maintenance

  9. Results indicate that the MMS19-XPD (show ERCC2 Proteins) protein complex is required for proper chromosome segregation, an abnormality of which could contribute to the pathogenesis in some cases of xeroderma pigmentosum.

  10. Cloning of the human MMS19 genes and functional complementation in Saccharomyces cerevisiae

MMS19 Protein Profile

Protein Summary

May play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER- transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. As part of the mitotic spindle- associated MMXD complex it plays a role in chromosome segregation.

Gene names and symbols associated with MMS19

  • minisatellites detected by probe MMS19 (Ms19)
  • MMS19 nucleotide excision repair homolog (S. cerevisiae) (MMS19)
  • MMS19 (MET18 S. cerevisiae) (Mms19)
  • 2410001K24Rik protein
  • 2610042O15Rik protein
  • AI316855 protein
  • C79368 protein
  • C86341 protein
  • hMMS19 protein
  • MET18 protein
  • MMS19 protein
  • Mms19l protein

Protein level used designations for MMS19

MMS19-like (MET18 homolog, S. cerevisiae) , MET18 homolog , MMS19 nucleotide excision repair protein homolog , MMS19-like protein , homolog of yeast MMS19

GENE ID SPECIES
111647 Mus musculus
477788 Canis lupus familiaris
100070717 Equus caballus
100157608 Sus scrofa
72199 Mus musculus
64210 Homo sapiens
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