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Meningioma 1 (MN1) contains two sets of CAG repeats. Additionally we are shipping MN1 Antibodies (37) and and many more products for this protein.
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MN1 deletion is associated with Craniofacial Abnormalities.
Chromosome 22q12.1 microdeletions involving the MN1 gene confirm it as a candidate gene for cleft palate.
MLL1 and DOT1L (show DOT1L Proteins) cooperate with meningioma-1 to induce acute myeloid leukemia (show BCL11A Proteins).
genotype-phenotype correlation among our patients and those previously reported with overlapping 22q12 deletions, we identified a 560 kb critical region containing the MN1 gene that is implicated in human cleft palate formation
these results suggest that deregulated MN1 expression contributes to the pathogenesis of pediatric B-ALL.
identified potential driver mutations in NF2 (neurofibromatosis type 2) and MN1 (meningioma 1).
cotransduction of an activated HOX (show MSH2 Proteins) gene (NUP98HOXD13) with MN1 induces a serially transplantable acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)).
MN1 overexpression independently predicts bad clinical outcome in CN-AML (show RUNX1 Proteins) patients
High MN1 expression confers worse prognosis in Chinese adult patients with de novo acute myeloid leukemia (show BCL11A Proteins).
Overexpression of MN1 confers resistance to chemotherapy, accelerates leukemia onset, and suppresses p53 (show TP53 Proteins) and Bim (show BCL2L11 Proteins) induction
Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4\\;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis.
meningioma (translocation balanced)
, meningioma chromosome region 1
, probable tumor suppressor protein MN1