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MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) ELISA Kits

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Additionally we are shipping MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Antibodies (30) and MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human MOBKL1B MOBKL1B 55233 Q9H8S9
Anti-Mouse MOBKL1B MOBKL1B 232157 Q921Y0
Anti-Rat MOBKL1B MOBKL1B 297387 Q3T1J9
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More ELISA Kits for MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Interaction Partners

Xenopus laevis MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. Data report the solution structure of the Mob1 protein from Xenopus laevis solved by heteronuclear multidimensional NMR.

Zebrafish MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. mats1 plays a critical role in regulating cell proliferation and apoptosis during early development in zebrafish[mats1]

Human MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. No relationship has been found between the MOBKL1B-NS5A interaction and hepatitis C virus replication.

  2. The RING ligase praja2 ubiquitylates and degrades Mob, a core component of NDR/LATS kinase and a positive regulator of the tumour-suppressor Hippo cascade.

  3. Mob1A and Mob1B are needed for cell abscission and centriole re-joining after telophase and cytokinesis.

  4. Results suggest that Mob1 (show MOBKL3 ELISA Kits) and the other mammalian orthologues of the mitotic exit network regulate mitotic progression by facilitating the timely mobilization of the chromosomal passenger complex to the spindle midzone.

  5. hMOB1A and hMOB1B are 2 LATS-binding proteins that may function as tumor suppressors in human cancer cells.

  6. Mats1 can rescue the lethality associated with loss of Mats function in Drosophila; As Mats1 is mutated in human tumors, Mats-mediated growth inhibition and tumor suppression is likely conserved in humans

  7. MATS1 mRNA expression is suppressed in tumor tissue and its low expression is associated with tumor growth, invasion and metastasis of colorectal cancer

Mouse (Murine) MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. MOB1A and MOB1B have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway.

MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Antigen Profile

Antigen Summary

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 (By similarity).

Gene names and symbols associated with MOBKL1B

  • MOB1, Mps One Binder kinase activator-like 1B (mobkl1b) antibody
  • MOB1, Mps One Binder kinase activator-like 1B (yeast) (MOBKL1B) antibody
  • MOB kinase activator 1A (mob1a) antibody
  • MOB kinase activator 1A (MOB1A) antibody
  • MOB kinase activator 1A (Mob1a) antibody
  • 4022402H07Rik antibody
  • C2orf6 antibody
  • MATS1 antibody
  • MOB1 antibody
  • MOB1A antibody
  • MOB4B antibody
  • Mobk1b antibody
  • Mobkl1b antibody
  • wu:fv69d04 antibody
  • zgc:56189 antibody

Protein level used designations for MOBKL1B

MOB1, Mps One Binder kinase activator-like 1B , Mob4B protein , mps one binder kinase activator-like 1B , MOB1, Mps One Binder kinase activator-like 1B (yeast) , mats1 , mobk1b , Mps one binder kinase activator-like 1B , mob1 homolog 1B , MOB1 Mps One Binder homolog A , mob1 alpha

GENE ID SPECIES
398675 Xenopus laevis
459544 Pan troglodytes
549780 Xenopus (Silurana) tropicalis
612924 Canis lupus familiaris
614611 Bos taurus
712156 Macaca mulatta
100005014 Danio rerio
100172677 Pongo abelii
55233 Homo sapiens
232157 Mus musculus
297387 Rattus norvegicus
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