You are viewing an incomplete version of our website. Please click to reload the website as full version.

MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteins (MOBKL1B)

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. Additionally we are shipping MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Antibodies (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MOBKL1B 55233 Q9H8S9
MOBKL1B 232157 Q921Y0
MOBKL1B 297387 Q3T1J9
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,531.83
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
Yeast Human Un-conjugated   100 μg Log in to see 9 to 14 Days
$369.79
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MOBKL1B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteins

  1. Human MOBKL1B Protein expressed in Escherichia coli (E. coli) - ABIN667320 : Lai, Wei, Shimizu, Ramos, Rohrbaugh, Nikolaidis, Ho, Li: Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. in Cell 2005 (PubMed)
    Show all 2 references for ABIN667320

More Proteins for MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Interaction Partners

Xenopus laevis MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. Data report the solution structure of the Mob1 protein from Xenopus laevis solved by heteronuclear multidimensional NMR.

Zebrafish MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. mats1 plays a critical role in regulating cell proliferation and apoptosis during early development in zebrafish[mats1]

Human MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. No relationship has been found between the MOBKL1B-NS5A interaction and hepatitis C virus replication.

  2. The RING ligase praja2 ubiquitylates and degrades Mob, a core component of NDR/LATS kinase and a positive regulator of the tumour-suppressor Hippo cascade.

  3. Mob1A and Mob1B (show MOB1B Proteins) are needed for cell abscission and centriole re-joining after telophase and cytokinesis.

  4. Results suggest that Mob1 (show MOBKL3 Proteins) and the other mammalian orthologues of the mitotic exit network regulate mitotic progression by facilitating the timely mobilization of the chromosomal passenger complex to the spindle midzone.

  5. hMOB1A and hMOB1B are 2 LATS-binding proteins that may function as tumor suppressors in human cancer cells.

  6. Mats1 can rescue the lethality associated with loss of Mats function in Drosophila; As Mats1 is mutated in human tumors, Mats-mediated growth inhibition and tumor suppression is likely conserved in humans

  7. MATS1 mRNA expression is suppressed in tumor tissue and its low expression is associated with tumor growth, invasion and metastasis of colorectal cancer

Mouse (Murine) MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) interaction partners

  1. MOB1A and MOB1B (show MOB1B Proteins) have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway.

MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) (MOBKL1B) Protein Profile

Protein Summary

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38 (By similarity).

Gene names and symbols associated with MOBKL1B

  • MOB1, Mps One Binder kinase activator-like 1B (mobkl1b)
  • MOB1, Mps One Binder kinase activator-like 1B (yeast) (MOBKL1B)
  • MOB kinase activator 1A (mob1a)
  • MOB kinase activator 1A (MOB1A)
  • MOB kinase activator 1A (Mob1a)
  • 4022402H07Rik protein
  • C2orf6 protein
  • MATS1 protein
  • MOB1 protein
  • MOB1A protein
  • MOB4B protein
  • Mobk1b protein
  • Mobkl1b protein
  • wu:fv69d04 protein
  • zgc:56189 protein

Protein level used designations for MOBKL1B

MOB1, Mps One Binder kinase activator-like 1B , Mob4B protein , mps one binder kinase activator-like 1B , MOB1, Mps One Binder kinase activator-like 1B (yeast) , mats1 , mobk1b , Mps one binder kinase activator-like 1B , mob1 homolog 1B , MOB1 Mps One Binder homolog A , mob1 alpha

GENE ID SPECIES
398675 Xenopus laevis
459544 Pan troglodytes
549780 Xenopus (Silurana) tropicalis
612924 Canis lupus familiaris
614611 Bos taurus
712156 Macaca mulatta
100005014 Danio rerio
100172677 Pongo abelii
55233 Homo sapiens
232157 Mus musculus
297387 Rattus norvegicus
Selected quality suppliers for MOB1, Mps One Binder Kinase Activator-Like 1B (Yeast) Proteins (MOBKL1B)
Did you look for something else?