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MYC Associated Factor X Proteins (MAX)

The protein encoded by MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. Additionally we are shipping MAX Antibodies (92) and MAX Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MAX 17187  
MAX 4149 P61244
MAX 60661 P52164
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Top MAX Proteins at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,357.67
Details
Yeast Cat His tag   1 mg Log in to see 56 to 66 Days
$2,357.67
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,361.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,377.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details

MAX Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
, , ,
Rat (Rattus)

Top referenced MAX Proteins

  1. Human MAX Protein expressed in Escherichia coli (E. coli) - ABIN666983 : Burbano, Hodges, Green, Briggs, Krause, Meyer, Good, Maricic, Johnson, Xuan, Rooks, Bhattacharjee, Brizuela, Albert, de la Rasilla, Fortea, Rosas, Lachmann, Hannon, Pääbo: Targeted investigation of the Neandertal genome by array-based sequence capture. in Science (New York, N.Y.) 2010 (PubMed)

  2. Human MAX Protein expressed in Baculovirus infected Insect Cells - ABIN2005345 : Mac Partlin, Homer, Robinson, McCormick, Crouch, Durant, Matheson, Hall, Gillespie, Brown: Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX. in Oncogene 2003 (PubMed)

More Proteins for MYC Associated Factor X (MAX) Interaction Partners

Fruit Fly (Drosophila melanogaster) MYC Associated Factor X (MAX) interaction partners

  1. We find that many biological activities of Myc (show MYC Proteins) do not, or only partly, require the association with Max--

Mouse (Murine) MYC Associated Factor X (MAX) interaction partners

  1. Myc (show MYC Proteins) represses C/EBPdelta (show CEBPD Proteins) expression by associating with the C/EBPdelta (show CEBPD Proteins) proximal promoter as a transient component of a repressive complex that includes Max and Miz1 (show PIAS2 Proteins)

  2. The switch from Mnt-Max to Myc (show MYC Proteins)-Max during bile duct ligation (cholestasis) and in hepatocytes treated with lithocholic acid is responsible for the induction in p53 (show TP53 Proteins) and cyclin D1 (show CCND1 Proteins) expression and contributes to apoptosis.

  3. the c-Myc (show MYC Proteins)-Max complex exerts its transcriptional regulatory role and hnRNP U (show HNRNPU Proteins) may be a coactivator of this transcriptional activator complex.

Human MYC Associated Factor X (MAX) interaction partners

  1. The introduction of wild-type MAX cDNA into PC12 cells significantly decreased MYC's ability to bind to canonical E-boxes, while pathogenic MAX proteins were not able to fully repress MYC (show MYC Proteins) activity. Further clinical and molecular evaluation of variant carriers corroborated the results obtained with the functional assessment.

  2. Celastrol and some of its quinone methidecontaining analogs directly inhibit c-Myc (show MYC Proteins)-Max heterodimers in tumor cells.

  3. We confirmed that these dimeric inhibitors directly bind to Myc (show MYC Proteins) blocking its interaction with Max and affect transcription of MYC (show MYC Proteins) dependent genes.

  4. MYC (show MYC Proteins) is part of a network of bHLHLZ proteins centered on the MYC (show MYC Proteins) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX (show MLX Proteins).

  5. Myc (show MYC Proteins) and its obligate heterodimeric partner, Max, are integral to the coordinated recruitment and post-translational modification of components of the core transcriptional machinery.

  6. Here we review the activities of MYC (show MYC Proteins), MNT (show MNT Proteins) and other MAX interacting proteins in the setting of T and B cell activation (show BLNK Proteins) and oncogenesis

  7. Delta Max, but not full-length Max, rescues Myc (show MYC Proteins)-dependent glycolytic gene expression upon induced EGFRvIII loss, and correlates with hnRNPA1 (show HNRNPA1 Proteins) expression and downstream Myc (show MYC Proteins)-dependent gene transcription in patients.

  8. Data show that Sirt1 (show SIRT1 Proteins), p53 (show TP53 Proteins), and p38(MAPK (show MAPK14 Proteins)) are involved in the detrimental phenotype of Max-null ESCs (show NR2E3 Proteins). Analyses revealed these proteins are involved at varying levels to one another in the hierarchy of the pathway leading to cell death in Max-null ESCs (show NR2E3 Proteins).

  9. New structural determinants for c-Myc specific heterodimerization with Max and development of a novel homodimeric c-Myc b-HLH-LZ.

  10. Max b-HLH-LZ can transduce into cells and inhibit c-Myc (show MYC Proteins) transcriptional activities

MAX Protein Profile

Protein Summary

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MYC Associated Factor X Proteins (MAX)

  • CG9648 gene product from transcript CG9648-RA (Max)
  • MYC associated factor X (max-a)
  • MYC associated factor X (MAX)
  • MYC associated factor X (max)
  • Max protein (Max)
  • MYC associated factor X (max-b)
  • MYC associated factor X (Max)
  • myc-associated factor X (max)
  • AA960152 protein
  • AI875693 protein
  • bHLHd4 protein
  • bHLHd5 protein
  • bHLHd6 protein
  • bHLHd7 protein
  • bHLHd8 protein
  • bHLHd9 protein
  • CG9648 protein
  • dmax protein
  • Dmel\\CG9648 protein
  • fa92b04 protein
  • fb52a04 protein
  • fb95h11 protein
  • max protein
  • wu:fa92b04 protein
  • wu:fb52a04 protein
  • wu:fb95h11 protein
  • xmax protein
  • xmax2 protein
  • xmax4 protein
  • zmax protein

Protein level used designations for MYC Associated Factor X Proteins (MAX)

CG9648-PA , CG9648-PC , Max-PA , Max-PC , Max homologue 2 , Myc binding protein Xmax4 , myc-associated factor X , protein max , xMAX , MYC associated factor X , myc-binding novel HLH/LZ protein , protein myn , class D basic helix-loop-helix protein 4 , Myc binding protein Xmax2

GENE ID SPECIES
40095 Drosophila melanogaster
373652 Xenopus laevis
452972 Pan troglodytes
493570 Xenopus (Silurana) tropicalis
100215471 Hydra magnipapillata
17187 Mus musculus
4149 Homo sapiens
504192 Xenopus laevis
100858676 Gallus gallus
609969 Canis lupus familiaris
540616 Bos taurus
60661 Rattus norvegicus
493947 Felis catus
30467 Danio rerio
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