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MIF encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. Additionally we are shipping MIF Antibodies (207) and MIF Kits (69) and many more products for this protein.
Showing 10 out of 57 products:
Human MIF Protein expressed in Escherichia coli (E. coli) - ABIN2667555
Calandra, Bernhagen, Metz, Spiegel, Bacher, Donnelly, Cerami, Bucala: MIF as a glucocorticoid-induced modulator of cytokine production. in Nature 1995
Show all 6 references for ABIN2667555
Mouse (Murine) MIF Protein expressed in Escherichia coli (E. coli) - ABIN2667556
Calandra, Froidevaux, Martin, Roger: Macrophage migration inhibitory factor and host innate immune defenses against bacterial sepsis. in The Journal of infectious diseases 2003
Show all 6 references for ABIN2667556
Human MIF Protein expressed in Escherichia coli (E. coli) - ABIN666683
Bucala: MIF rediscovered: cytokine, pituitary hormone, and glucocorticoid-induced regulator of the immune response. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997
Show all 3 references for ABIN666683
Mouse (Murine) MIF Protein expressed in Human Cells - ABIN2007258
Hoi, Iskander, Morand: Macrophage migration inhibitory factor: a therapeutic target across inflammatory diseases. in Inflammation & allergy drug targets 2007
Show all 3 references for ABIN2007258
Mouse (Murine) MIF Protein expressed in Escherichia coli (E. coli) - ABIN2007260
Bach, Deuster, Balzer-Geldsetzer, Meyer, Dodel, Bacher: The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors. in Cancer 2009
Show all 3 references for ABIN2007260
Human MIF Protein expressed in Human Cells - ABIN2002425
Rendon, Willer, Zundel, Mitchell: Mechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation. in Experimental and molecular pathology 2009
Show all 2 references for ABIN2002425
Human MIF Protein expressed in Escherichia coli (E. coli) - ABIN1047347
Weiser, Temple, Witek-Giannotti, Remold, Clark, David: Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor. in Proceedings of the National Academy of Sciences of the United States of America 1989
Show all 2 references for ABIN1047347
Human MIF Protein expressed in Escherichia coli (E. coli) - ABIN2667558
Babu, Chetal, Kumar: Macrophage migration inhibitory factor: a potential marker for cancer diagnosis and therapy. in Asian Pacific journal of cancer prevention : APJCP 2012
Show all 2 references for ABIN2667558
MIF was found to be essential for axis formation and neural development of Xenopus embryos.
Data show that the mif pathway is required for both sensory hair cell (HC) and sensory neuronal cell survival in the ear, for HC differentiation, semicircular canal formation, statoacoustic ganglion (SAG (show SAG Proteins)) development, and lateral line HC differentiation.
MIF inhibits the myoblast differentiation by affecting the cell cycle progression, but does not affect proliferation.
this paper shows that the detrimental effect of MIF knockout was associated with accentuated loss in cardiac autophagy with aging
our results suggest that MIF promotes mCSC (show SLC25A25 Proteins) survival, proliferation and endothelial differentiation through the activation of the PI3K/Akt (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) and AMPK (show PRKAA1 Proteins) signaling pathways.
Posttranslational modification of MIF by S-nitrosation results in intracellular accumulation and protection from myocardial ischemia reperfusion injury.
Data show that the siRNA-induced macrophage migration inhibitory factor (MIF) reduction in murine mammary cancer line 4T1 and human breast cancer line MDA-MB-231 resulted in significant reduction of cell proliferation and increase of apoptosis.
High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates.
The deletion of the MIF gene led to reduced behavioural despair in mice of both sexes and IFN-gamma (show IFNG Proteins) mRNA levels were reduced in the hippocampus of the MIF KO mice.
In D-galactosamine-sensitized mice CP+Cu(II) increased the LPS (show TLR4 Proteins)-induced lethality from 54 to 100%, while administration of antibodies against MIF prevented the lethal effect. The enhancement by CP+Cu(II) of the pro-inflammatory signal of MIF is discussed.
data suggest that the MIF-Notch (show NOTCH1 Proteins) axis may play an important role in the pathogenesis of experimental autoimmune uveitis
The functional role of MIF in cell recruitment was investigated by a chemotaxis assay and by flow cytometry of labeled macrophages that were injected into Mif-/-and wildtype mice
'low' serum Lipoprotein(a), mediating autoimmune activation, is a major determinant of metabolic disease risk and death. Damaged MIF (show AMH Proteins) protein and more complex autoimmune activation in women may be responsible from lack of relationship to Metbolic syndrome/mortality.
Study revealed that TNF (show TNF Proteins) gene -308G[A polymorphism is strongly associated with a susceptibility to dysmenorrhea in Turkish population; however, no relation was found for MIF (show AMH Proteins) gene -173G[C polymorphism.
structural modeling predicts a new MIF (show AMH Proteins)(CD74 (show CD74 Proteins))3 dodecamer that may provide the basis for increased MIF (show AMH Proteins) potency and the requirement for ~3-fold excess RTL1000 to achieve full antagonism
High MIF (show AMH Proteins) levels and MIF (show AMH Proteins) -173G/C gene polymorphism are powerful predictors of the severity of sepsis and its outcome.
miR (show MLXIP Proteins)-608 overexpression inhibits the malignant behavior of glioma stem cells by downregulating MIF (show AMH Proteins).
macrophage migration inhibitory factor (MIF) was regulated directly by miR451 and was a critical mediator of the biological effects of miR451 in neuroblastoma (show ARHGEF16 Proteins).
MIF (show AMH Proteins) gene -173 G/C single nucleotide polymorphisms implicate in genetic susceptibility to TB, and GC+CC of MIF (show AMH Proteins) -173 site increases the risk of TB. We also found that no correlation between -173 G/C single nucleotide polymorphism and retreatment cases of TB in Yunnan Province population of China.
Significant differences exist in plasma MIF (show AMH Proteins) levels between obese and non-obese women with and without polycystic ovary syndrome.
Genetic polymorphism of rs755622 in MIF is associated with increased risk of gestational diabetes and insulin resistance in Han Chinese women.
miR (show MLXIP Proteins)-451 was down-regulated in renal cell carcinoma (show MOK Proteins) and correlated with histological grade and lymphatic metastasis. MIF (show AMH Proteins) was identified as a target of miR (show MLXIP Proteins)-451, and down-regulation of MIF (show AMH Proteins) could mimic the suppressive functions of miR (show MLXIP Proteins)-451.
The objective of the present study was to determine if SNPs in 5' region of bovine MIF affects its promoter activity.
MIF plays a role in early embryo development, and further characterization of MIF expression and its regulation in the endometrium will add significantly to our understanding of early embryo-uterine interactions
The diverse actions of MIF within the immuno-neuroendocrine system may be a result of its occurrence in different isoforms and oligomerization states.
The purification of macrophage migration inhibitory factor (MIF) from bovine brain cytosol and its partial characterization are reported.
Transcription of MIF is induced by activation of PPARgamma2 (show PPARG Proteins) and inhibited by excessive resistin (show RETN Proteins).
The high activity of MIF in the maternal and fetal tissues throughout placentation and its expression in the nonpregnant uterus indicate a regulatory role for MIF during embryo receptivity and epitheliochorial placentation
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
, L-dopachrome tautomerase
, Phenylpyruvate tautomerase
, macrophage migration inhibitory factor
, phenylpyruvate tautomerase
, Macrophage migration inhibitory factor
, delayed early response protein 6
, glycosylation-inhibiting factor
, glutathione-binding 13 kDa protein