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Macrophage Receptor with Collagenous Structure Proteins (MARCO)

The protein encoded by MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. Additionally we are shipping MARCO Antibodies (83) and MARCO Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MARCO 17167 Q60754
MARCO 8685 Q9UEW3
Rat MARCO MARCO 367391  
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Top MARCO Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$3,151.50
Details

MARCO Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
,
Human ,
,

Top referenced MARCO Proteins

  1. Mouse (Murine) MARCO Protein expressed in Human Cells - ABIN2007616 : Arredouani, Kobzik: The structure and function of marco, a macrophage class a scavenger receptor. in Cellular and molecular biology (Noisy-le-Grand, France) 2005 (PubMed)

More Proteins for Macrophage Receptor with Collagenous Structure (MARCO) Interaction Partners

Mouse (Murine) Macrophage Receptor with Collagenous Structure (MARCO) interaction partners

  1. MARCO Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway

  2. our data demonstrate that MARCO differentially affects TLR-induced DC activation and suggest targeting of MARCO could lead to different outcomes that depend on the inflammatory context encountered by dendritic cells.

  3. Vaccinia virus bound directly to MARCO, and overexpression of MARCO increased susceptibility to vaccinia infection.

  4. MARCO-/- dendritic cells demonstrated enhanced migratory capacity in response to CCL-21 (show CCL21 Proteins) in vitro.

  5. herpes simplex virus type 1 binds to MARCO to enhance its capacity for disease.

  6. results indicate that accumulation of SQSTM1 (show SQSTM1 Proteins) leads to increased activation of NFE2L2 (show NFE2L2 Proteins) and the subsequent increase in MARCO and MSR1 (show MSR1 Proteins)

  7. this study, we confirm that tolerized mouse bone marrow-derived macrophages selectively increase expression of MARCO and increase phagocytosis

  8. MARCO is an important component of anti-Streptococcus pneumoniae responses in murine nasopharyngeal macrophages during bacterial colonization.

  9. Fetuin-A (show AHSG Proteins)-containing calciprotein particles facilitate the clearance of mineral debris by macrophages via SR-A (show MSR1 Proteins).

  10. These results indicate that MARCO suppresses a protective early inflammatory response to influenza, which modulates viral clearance and delays recovery.

Human Macrophage Receptor with Collagenous Structure (MARCO) interaction partners

  1. Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI (show MSR1 Proteins) and MARCO.

  2. None of the nonsynonymous variants discovered by resequencing of the structurally similar MARCO were associated with lung function or risk of COPD (show ARCN1 Proteins).

  3. Vaccinia virus bound directly to MARCO, and overexpression of MARCO increased susceptibility to vaccinia infection.

  4. Significant associations of four SNPs and haplotypes with antibody response to cholera vaccine in three genes, MARCO, TNFAIP3 (show TNFAIP3 Proteins) and CXCL12 (show CXCL12 Proteins).

  5. herpes simplex virus type 1 binds to MARCO to enhance its capacity for disease.

  6. We identified 9 non-synonymous variants in the MARCO gene and showed that these variants are not major risk factors for COPD (show ARCN1 Proteins) or lung infection. H101Q heterozygotes had increased sepsis risk.

  7. Polymorphisms within the human class A scavenger receptor MARCO correlate with susceptibility/resistance to tuberculosis in a Gambian population.

  8. In this review, we showed that SR-A (show MSR1 Proteins) and MARCO trigger intracellular signaling, modulating pro-inflammatory and microbicidal activities of macrophages.

  9. This review demonstrated that class A SR and MARCO are major pattern recognition receptors mediating opsonin-independent phagocytosis.

  10. genetic variants in MARCO gene were associated with pulmonary tuberculosis susceptibility in Chinese Han population

MARCO Protein Profile

Protein Summary

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Gene names and symbols associated with MARCO

  • macrophage receptor with collagenous structure (MARCO)
  • macrophage receptor with collagenous structure (Marco)
  • AI323439 protein
  • Ly112 protein
  • SCARA2 protein

Protein level used designations for MARCO

macrophage receptor MARCO , scavenger receptor class A member 2 , scavenger receptor class A, member 2 , putative scavenger receptor MARCO

GENE ID SPECIES
100516298 Sus scrofa
17167 Mus musculus
8685 Homo sapiens
367391 Rattus norvegicus
395488 Gallus gallus
476117 Canis lupus familiaris
100716503 Cavia porcellus
505632 Bos taurus
101834359 Mesocricetus auratus
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