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MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Kits (18) and Macrophage Scavenger Receptor 1 Proteins (15) and many more products for this protein.
Showing 10 out of 205 products:
Mouse (Murine) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for EIA, FACS - ABIN181780
de Villiers, Fraser, Hughes, Doyle, Gordon: Macrophage-colony-stimulating factor selectively enhances macrophage scavenger receptor expression and function. in The Journal of experimental medicine 1994
Show all 11 references for ABIN181780
Mouse (Murine) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN319577
Hughes, Fraser, Gordon: Murine macrophage scavenger receptor: in vivo expression and function as receptor for macrophage adhesion in lymphoid and non-lymphoid organs. in European journal of immunology 1995
Show all 10 references for ABIN319577
Mouse (Murine) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN181777
Bell, Lopez-Gonzalez, Lawson, Hughes, Fraser, Gordon, Perry: Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS. in Journal of neurocytology 1995
Show all 6 references for ABIN181777
Mouse (Murine) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for EIA, Func - ABIN181779
Daugherty, Whitman, Block, Rateri: Polymorphism of class A scavenger receptors in C57BL/6 mice. in Journal of lipid research 2001
Show all 6 references for ABIN181779
Mouse (Murine) Monoclonal Macrophage Scavenger Receptor 1 Primary Antibody for FACS - ABIN181781
Fraser, Hughes, Gordon: Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. in Nature 1993
Show all 6 references for ABIN181781
Human Polyclonal Macrophage Scavenger Receptor 1 Primary Antibody for ICC, IHC (fro) - ABIN314198
Piccolo, Vetrini, Mithbaokar, Grove, Bertin, Palmer, Ng, Brunetti-Pierri: SR-A and SREC-I are Kupffer and endothelial cell receptors for helper-dependent adenoviral vectors. in Molecular therapy : the journal of the American Society of Gene Therapy 2013
Show all 2 references for ABIN314198
Human Polyclonal Macrophage Scavenger Receptor 1 Primary Antibody for WB - ABIN1537159
Chen, Li, Zhu: AMP-activated protein kinase attenuates oxLDL uptake in macrophages through PP2A/NF-?B/LOX-1 pathway. in Vascular pharmacology 2015
We also demonstrate that across the human genome, the presence of MSR1 repeats in the promoters or first introns of genes is associated with greater population variability in gene expression indicating that copy number variation of MSR1s is a generic controller of gene expression and promises to provide new insights into our understanding of gene expression regulation
Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (show MARCO Antibodies).
The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.
Cyr61 (show CYR61 Antibodies) promotes CD204 expression and the migration of macrophages via MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies) pathway in esophageal squamous cell carcinoma
miR (show MLXIP Antibodies)-29a promotes scavenger receptor A expression by targeting QKI (show QKI Antibodies) during monocyte-macrophage differentiation.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP Antibodies) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP Antibodies) oligomer in microglia.
The truncating variant Arg293X in the gene encoding SRA (show SRA1 Antibodies)-I/II was associated with reduced lung function and with increased risk of COPD (show ARCN1 Antibodies) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (show SOD1 Antibodies)-3 E1I1 heterozygotes.
monomeric collagen type I via CD204 induces phospho-Akt (show AKT1 Antibodies) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.
There was a significant negative correlation between the number of CD163 (show CD163 Antibodies)(+), CD204(+) or CD206 (show MRC1 Antibodies)(+) alveolar macrophages.
rs6966 (3' UTR of PPP1R13L, chr 19q13.32, P = 4.55 x 10(-9)) and rs414580 (intron 2 of MSR1, chr 8p22, P = 6.09 x 10(-8)) were significantly associated with ALL.
Our findings demonstrated that ClC-3 (show CLCN3 Antibodies) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 Antibodies)/p38 MAPK (show MAPK14 Antibodies) dependent SR-A expression and foam cell formation
FAP (show FAP Antibodies)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.
Macrophages regulate FX plasma levels in an SR-AI-dependent manner.
The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.
these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.
Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP Antibodies) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP Antibodies) oligomer in an immortalized microglia cell line.
SR-A does not induce cytokine production, but mediates inhibition of LPS (show TLR4 Antibodies)-stimulated production of IL-6 (show IL6 Antibodies) and IL-12 (show IL12A Antibodies)
The antagonism between SR-A and RAGE (show AGER Antibodies) contributes to the pathogenesis of diabetic retinopathy by nurturing a disease-prone macrophage phenotype.
our data indicate that SR-A localizes in LRs (show LARS Antibodies) and that LRs (show LARS Antibodies) are required to couple SR-A to PLA2 (show PLA2G2A Antibodies) activation during SRA-mediated macrophage attachment.
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
macrophage scavenger receptor 1
, macrophage scavenger receptor types I and II-like
, macrophage acetylated LDL receptor I and II
, macrophage scavenger receptor type III
, macrophage scavenger receptor types I and II
, scavenger receptor class A member 1
, scavenger receptor class A, member 1
, scavenger receptor type A
, macrophage scavenger receptor type I