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MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. Additionally we are shipping Macrophage Scavenger Receptor 1 Antibodies (198) and Macrophage Scavenger Receptor 1 Proteins (15) and many more products for this protein.
Showing 9 out of 20 products:
Human Macrophage Scavenger Receptor 1 ELISA Kit for Sandwich ELISA - ABIN417678
Zuo, Yu, Guo, Wang, Qian, Yi, Lu, Lv, Subjeck, Zhou, Sanyal, Chen, Wang: Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. in Hepatology (Baltimore, Md.) 2013
Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (show MARCO ELISA Kits).
The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.
Cyr61 (show CYR61 ELISA Kits) promotes CD204 expression and the migration of macrophages via MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway in esophageal squamous cell carcinoma
miR (show MLXIP ELISA Kits)-29a promotes scavenger receptor A expression by targeting QKI (show QKI ELISA Kits) during monocyte-macrophage differentiation.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP ELISA Kits) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP ELISA Kits) oligomer in microglia.
The truncating variant Arg293X in the gene encoding SRA (show SRA1 ELISA Kits)-I/II was associated with reduced lung function and with increased risk of COPD (show ARCN1 ELISA Kits) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (show SOD1 ELISA Kits)-3 E1I1 heterozygotes.
monomeric collagen type I via CD204 induces phospho-Akt (show AKT1 ELISA Kits) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.
There was a significant negative correlation between the number of CD163 (show CD163 ELISA Kits)(+), CD204(+) or CD206 (show MRC1 ELISA Kits)(+) alveolar macrophages.
rs6966 (3' UTR of PPP1R13L, chr 19q13.32, P = 4.55 x 10(-9)) and rs414580 (intron 2 of MSR1, chr 8p22, P = 6.09 x 10(-8)) were significantly associated with ALL.
Our data suggest that inefficient folding of SR-AI variants with truncated SRCR domain was recognized by the endoplasmic reticulum associated degradation which leads to the immature N- glycosylation and intracellular retention
Our findings demonstrated that ClC-3 (show CLCN3 ELISA Kits) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (show MAPK8 ELISA Kits)/p38 MAPK (show MAPK14 ELISA Kits) dependent SR-A expression and foam cell formation
FAP (show FAP ELISA Kits)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.
Macrophages regulate FX plasma levels in an SR-AI-dependent manner.
The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.
these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.
Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (show APP ELISA Kits) to SR-A, thereby promoting glial phagocytosis of Abeta (show APP ELISA Kits) oligomer in an immortalized microglia cell line.
SR-A does not induce cytokine production, but mediates inhibition of LPS (show TLR4 ELISA Kits)-stimulated production of IL-6 (show IL6 ELISA Kits) and IL-12 (show IL12A ELISA Kits)
The antagonism between SR-A and RAGE (show AGER ELISA Kits) contributes to the pathogenesis of diabetic retinopathy by nurturing a disease-prone macrophage phenotype.
our data indicate that SR-A localizes in LRs (show LARS ELISA Kits) and that LRs (show LARS ELISA Kits) are required to couple SR-A to PLA2 (show PLA2G2A ELISA Kits) activation during SRA-mediated macrophage attachment.
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
macrophage scavenger receptor 1
, macrophage scavenger receptor types I and II-like
, macrophage acetylated LDL receptor I and II
, macrophage scavenger receptor type III
, macrophage scavenger receptor types I and II
, scavenger receptor class A member 1
, scavenger receptor class A, member 1
, scavenger receptor type A
, macrophage scavenger receptor type I