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Mahogunin, Ring Finger 1 Proteins (MGRN1)

Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.[supplied by OMIM, Apr 2004].. Additionally we are shipping Mahogunin RING Finger Protein 1 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MGRN1 23295 O60291
Rat MGRN1 MGRN1 302938 Q5XIQ4
MGRN1 17237 Q9D074
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Top Mahogunin RING Finger Protein 1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MGRN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Mahogunin, Ring Finger 1 (MGRN1) Interaction Partners

Human Mahogunin, Ring Finger 1 (MGRN1) interaction partners

  1. Mahogunin-mediated alpha-tubulin (show TUBA4A Proteins) ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation.

  2. data suggest that MGRN1 selectively targets misfolded proteins for degradation and may exhibit viable therapeutic potential for the treatment of spongiform neurodegeneration

  3. It therefore seems probable that the role of MGRN1 in the adrenal relates to the trafficking and/or degradation of the melanocortin 2 receptor.

  4. a role for Mahogunin in a proteasome-independent ubiquitylation pathway: TSG101 (show TSG101 Proteins) is a specific Mahogunin substrate

  5. Study shows that both (Ctm)PrP and cyPrP can interact with and disrupt the function of Mahogunin (Mgrn), a cytosolic ubiquitin ligase whose loss causes spongiform neurodegeneration.

Mouse (Murine) Mahogunin, Ring Finger 1 (MGRN1) interaction partners

  1. Findings suggest that mahogunin ring finger-1 contributes to the clearance of toxic mutant copper-zinc superoxide dismutase (show SOD1 Proteins) inclusions likely through autophagic pathway.

  2. Mahogunin-mediated alpha-tubulin (show TUBA4A Proteins) ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation.

  3. ATRN (show ATRN Proteins) also has no effect on prion (show PRNP Proteins) disease onset or progression and discuss possible mechanisms that could cause vacuolation of the central nervous system in Mgrn1 and Atrn (show ATRN Proteins) null mutant mice

  4. pigment-type switching likely requires MGRN1's ubiquitin ligase activity but not its ability to bind TSG101 or NEDD4.

  5. Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase (show MUL1 Proteins) do not influence prion (show PRNP Proteins) disease.

  6. the md and mg mutations rescue the A(y) phenotypes by a primarily cAMP-independent mechanism promoting trafficking of MC4R and likely MC1R away from the lysosome toward the cell surface.

  7. positional cloning of mahoganoid, encoding a novel 494-amino acid protein containing a C3HC4 RING (really interesting new gene) domain that may function as an E3 ubiquitin ligase (show MUL1 Proteins)

  8. a null mutation for mahoganoid causes a similar age-dependent neuropathology that includes many features of prion (show PRNP Proteins) diseases but without accumulation of protease-resistant prion protein (show PRNP Proteins)

  9. Mahoganoid mutation (Mgrn1md) on insulin (show INS Proteins) sensitivity suggests that Mgrn1md may be increasing insulin (show INS Proteins) sensitivity via the hypothalamic melanocortin-3 receptor (show MC3R Proteins) pathway.

  10. Mgrn1 mutant embryos show abnormal expression of asymmetrically expressed genes involved in LR patterning.

Mahogunin RING Finger Protein 1 (MGRN1) Protein Profile

Protein Summary

Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.

Gene names and symbols associated with MGRN1

  • mahogunin ring finger 1, E3 ubiquitin protein ligase (MGRN1)
  • mahogunin ring finger 1, E3 ubiquitin protein ligase (mgrn1)
  • mahogunin, ring finger 1b (mgrn1b)
  • mahogunin, ring finger 1 (LOC100342669)
  • mahogunin, ring finger 1 (MGRN1)
  • mahogunin ring finger 1, E3 ubiquitin protein ligase (Mgrn1)
  • mahogunin, ring finger 1 (Mgrn1)
  • mahogunin, ring finger 1a (mgrn1a)
  • 2610042J20Rik protein
  • md protein
  • mgrn1 protein
  • mKIAA0544 protein
  • nc protein
  • RGD1311862 protein
  • RNF156 protein
  • wu:fi38c03 protein
  • zgc:55978 protein

Protein level used designations for MGRN1

mahogunin, ring finger 1 , probable E3 ubiquitin-protein ligase MGRN1 , E3 ubiquitin-protein ligase MGRN1 , RING finger protein 156 , mahogunin RING finger protein 1 , mahogunin ring finger protein 1 , mahoganoid

GENE ID SPECIES
453884 Pan troglodytes
479863 Canis lupus familiaris
549665 Xenopus (Silurana) tropicalis
553327 Danio rerio
100342669 Oryctolagus cuniculus
100471785 Ailuropoda melanoleuca
100541624 Meleagris gallopavo
100601520 Nomascus leucogenys
398990 Xenopus laevis
23295 Homo sapiens
100049682 Sus scrofa
616130 Bos taurus
302938 Rattus norvegicus
416660 Gallus gallus
17237 Mus musculus
793939 Danio rerio
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