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anti-Major Histocompatibility Complex, Class I-Related (MR1) Antibodies

non-MHC-linked class I-related gene [RGD, Feb 2006].. Additionally we are shipping MR1 Proteins (9) and MR1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MR1 3140 Q95460
MR1 15064 Q8HWB0
MR1 25119 O19477
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Top anti-MR1 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$320.68
Details
Human Mouse PE FACS 100 Tests Log in to see 10 to 12 Days
$320.68
Details
Human Mouse APC FACS, ICFC 100 Tests Log in to see 10 to 12 Days
$331.55
Details
Human Mouse Un-conjugated FACS, IHC 100 μg Log in to see 10 to 12 Days
$271.76
Details
Human Rabbit Un-conjugated WB MR1 Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the MR1 antibody detected the MR1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MR1 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$383.17
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . Immunofluorescence of monoclonal antibody to MR1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MR1 is approximately 1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details

MR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-MR1 Antibodies

  1. Human Monoclonal MR1 Primary Antibody for FACS - ABIN2665876 : Gold, Eid, Smyk-Pearson, Eberling, Swarbrick, Langley, Streeter, Lewinsohn, Lewinsohn: Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress. in Mucosal immunology 2012 (PubMed)
    Show all 11 references for ABIN2665876

  2. Human Monoclonal MR1 Primary Antibody for FACS, ICFC - ABIN2658367 : Meierovics, Yankelevich, Cowley: MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 11 references for ABIN2658367

  3. Human Monoclonal MR1 Primary Antibody for FACS, IHC - ABIN2665278 : Gold, Lewinsohn: Co-dependents: MR1-restricted MAIT cells and their antimicrobial function. in Nature reviews. Microbiology 2012 (PubMed)
    Show all 11 references for ABIN2665278

  4. Human Monoclonal MR1 Primary Antibody for FACS - ABIN2662807 : Young, Gapin: Mucosal associated invariant T cells: don't forget your vitamins. in Cell research 2013 (PubMed)
    Show all 11 references for ABIN2662807

More Antibodies against MR1 Interaction Partners

Human Major Histocompatibility Complex, Class I-Related (MR1) interaction partners

  1. Data show that the major histocompatibility complex, class I-related protein (MR1) antigen presentation is characterized by a rapid 'off-on-off' mechanism that is strictly dependent on antigen availability.

  2. endosome-mediated trafficking of MR1 allows for selective sampling of the intracellular environment

  3. Studies indicate that the antigen-presenting molecules CD1 (show CD1A Antibodies) and MHC class I-related protein (MR1) display lipids and small molecules to T cells.

  4. Data indicate that high expression of CD26 (show DPP4 Antibodies) ia a specific markers to define major histocompatibility complex, class I-like sequence protein MR1-restricted mucosa-associated invariant T (MAIT) cells.

  5. Mucosal-associated invariant T cell adaptation was a direct consequence of exposure to various exogenous MR1-restricted epitopes.

  6. [review] Mucosal-associated invariant T-cell (MAIT) T-cell antigen receptor recognizes riboflavin and folic acid metabolites bound by MR1 in a conserved docking mode and thus acts like a pattern recognition receptor.

  7. MR1 tetramers allow precise phenotypic characterization of human and mouse mucosal-associated invariant T cells.

  8. Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress.

  9. metabolites of vitamin B represent a class of antigen that are presented by MR1 for MAIT-cell immunosurveillance; as many vitamin biosynthetic pathways are unique to bacteria and yeast, data suggest that MAIT cells use these metabolites to detect microbial infection

  10. Mutagenesis of MR1 showed that only two residues, which were centrally positioned and on opposing sides of the antigen-binding cleft of MR1, were essential for MAIT cell activation

Mouse (Murine) Major Histocompatibility Complex, Class I-Related (MR1) interaction partners

  1. MR1 tetramers allow precise phenotypic characterization of human and mouse mucosal-associated invariant T cells.

  2. differential contribution of particular amino acids to the MAIT TCR-MR1 interaction based upon the presence of bacteria

  3. Data suggest that constitutive expression of MR1 may be detrimental for maintenance of immune homeostasis in the gut (show GUSB Antibodies) and/or detection of pathogenic bacteria in mucosal tissues.

  4. fact that MR1 seems mainly intracellular might offer clues as to the process, given the precedence in other class I molecules

  5. Gene silencing of myofibrillogenesis regulator-1 by adenovirus-delivered small interfering RNA suppresses cardiac hypertrophy induced by angiotensin II in mice.

  6. MR1 protein can associate with beta(2)-microglobulin (show B2M Antibodies)

  7. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

  8. Analysis of murine MR1 expressed in a murine cell line reveals that MR1 associates with the peptide-loading complex, indicating that MR1 uses the same cellular assembly machinery as do classical class I molecules.

  9. MR1 has an antigen presentation function

  10. HA peptides are expressed by EGCs and recognized by CD8 T cells that express a T-cell receptor (TCR) specific for Kd:HA512-520 (CL4) or CD4 T cells that express a TCR specific for IEd:HA107-119 (6.5), respectively.

MR1 Antigen Profile

Protein Summary

non-MHC-linked class I-related gene

Gene names and symbols associated with MR1

  • major histocompatibility complex, class I-related MR1 (MR1) antibody
  • major histocompatibility complex, class I-related (MR1) antibody
  • major histocompatibility complex, class I-related (mr1) antibody
  • major histocompatibility complex, class I-related (Mr1) antibody
  • DKFZp468C1823 antibody
  • H2ls antibody
  • Hlals antibody
  • MGC154362 antibody
  • MR1 antibody
  • YFV antibody

Protein level used designations for MR1

MHC Rfp-Y class I alpha chain , MHC class I-related protein , major histocompatibility complex class I-related gene protein , major histocompatibility complex class I-related protein variant 550 , major histocompatibility complex, class I-related , Major histocompatibility complex class I-related gene protein , MHC class I-like antigen MR-1 , MHC class I-related gene protein , MHC class-I related-gene protein , class I histocompatibility antigen-like protein , major histocompatibility complex, class I-like sequence , MCH class I , histocompatibility-2 complex class 1-like sequence , MHC class I-like sequence , MHC class I related protein, MR1B1 isoform

GENE ID SPECIES
427746 Gallus gallus
506206 Bos taurus
779227 Xenopus laevis
100145005 Xenopus (Silurana) tropicalis
100172054 Pongo abelii
3140 Homo sapiens
15064 Mus musculus
25119 Rattus norvegicus
457562 Pan troglodytes
Selected quality suppliers for anti-MR1 (MR1) Antibodies
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