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Major Histocompatibility Complex, Class I-Related Proteins (MR1)

non-MHC-linked class I-related gene [RGD, Feb 2006].. Additionally we are shipping MR1 Antibodies (33) and MR1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MR1 3140 Q95460
MR1 15064 Q8HWB0
MR1 25119 O19477
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Top MR1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,735.33
Details
Yeast Pongo pygmaeus His tag   1 mg Log in to see 56 to 66 Days
$2,735.33
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,735.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

More Proteins for Major Histocompatibility Complex, Class I-Related (MR1) Interaction Partners

Human Major Histocompatibility Complex, Class I-Related (MR1) interaction partners

  1. results suggest that high expression of MR-1 is involved in hepatocellular carcinoma progression

  2. Data show that the major histocompatibility complex, class I-related protein (MR1) antigen presentation is characterized by a rapid 'off-on-off' mechanism that is strictly dependent on antigen availability.

  3. endosome-mediated trafficking of MR1 allows for selective sampling of the intracellular environment

  4. Studies indicate that the antigen-presenting molecules CD1 (show CD1A Proteins) and MHC class I-related protein (MR1) display lipids and small molecules to T cells.

  5. Data indicate that high expression of CD26 (show DPP4 Proteins) ia a specific markers to define major histocompatibility complex, class I-like sequence protein MR1-restricted mucosa-associated invariant T (MAIT) cells.

  6. Mucosal-associated invariant T cell adaptation was a direct consequence of exposure to various exogenous MR1-restricted epitopes.

  7. [review] Mucosal-associated invariant T-cell (MAIT) T-cell antigen receptor recognizes riboflavin and folic acid metabolites bound by MR1 in a conserved docking mode and thus acts like a pattern recognition receptor.

  8. MR1 tetramers allow precise phenotypic characterization of human and mouse mucosal-associated invariant T cells.

  9. Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress.

  10. metabolites of vitamin B represent a class of antigen that are presented by MR1 for MAIT-cell immunosurveillance; as many vitamin biosynthetic pathways are unique to bacteria and yeast, data suggest that MAIT cells use these metabolites to detect microbial infection

Mouse (Murine) Major Histocompatibility Complex, Class I-Related (MR1) interaction partners

  1. MR1 tetramers allow precise phenotypic characterization of human and mouse mucosal-associated invariant T cells.

  2. differential contribution of particular amino acids to the MAIT TCR-MR1 interaction based upon the presence of bacteria

  3. Data suggest that constitutive expression of MR1 may be detrimental for maintenance of immune homeostasis in the gut (show GUSB Proteins) and/or detection of pathogenic bacteria in mucosal tissues.

  4. fact that MR1 seems mainly intracellular might offer clues as to the process, given the precedence in other class I molecules

  5. Gene silencing of myofibrillogenesis regulator-1 by adenovirus-delivered small interfering RNA suppresses cardiac hypertrophy induced by angiotensin II in mice.

  6. MR1 protein can associate with beta(2)-microglobulin (show B2M Proteins)

  7. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

  8. Analysis of murine MR1 expressed in a murine cell line reveals that MR1 associates with the peptide-loading complex, indicating that MR1 uses the same cellular assembly machinery as do classical class I molecules.

  9. MR1 has an antigen presentation function

  10. HA peptides are expressed by EGCs and recognized by CD8 T cells that express a T-cell receptor (TCR) specific for Kd:HA512-520 (CL4) or CD4 T cells that express a TCR specific for IEd:HA107-119 (6.5), respectively.

MR1 Protein Profile

Protein Summary

non-MHC-linked class I-related gene

Gene names and symbols associated with MR1

  • major histocompatibility complex, class I-related MR1 (MR1)
  • major histocompatibility complex, class I-related (MR1)
  • major histocompatibility complex, class I-related (mr1)
  • major histocompatibility complex, class I-related (Mr1)
  • DKFZp468C1823 protein
  • H2ls protein
  • Hlals protein
  • MGC154362 protein
  • MR1 protein
  • YFV protein

Protein level used designations for MR1

MHC Rfp-Y class I alpha chain , MHC class I-related protein , major histocompatibility complex class I-related gene protein , major histocompatibility complex class I-related protein variant 550 , major histocompatibility complex, class I-related , Major histocompatibility complex class I-related gene protein , MHC class I-like antigen MR-1 , MHC class I-related gene protein , MHC class-I related-gene protein , class I histocompatibility antigen-like protein , major histocompatibility complex, class I-like sequence , MCH class I , histocompatibility-2 complex class 1-like sequence , MHC class I-like sequence , MHC class I related protein, MR1B1 isoform

GENE ID SPECIES
427746 Gallus gallus
506206 Bos taurus
779227 Xenopus laevis
100145005 Xenopus (Silurana) tropicalis
100172054 Pongo abelii
3140 Homo sapiens
15064 Mus musculus
25119 Rattus norvegicus
457562 Pan troglodytes
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