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anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antibodies

HLA-DMA belongs to the HLA class II alpha chain paralogues. Additionally we are shipping Major Histocompatibility Complex, Class II, DM alpha Proteins (3) and Major Histocompatibility Complex, Class II, DM alpha Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID
HLA-DMA 294274
HLA-DMA 14998
HLA-DMA 3108
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Top anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HLA-DMA AntibodyTitration: 1.0 µg/mL  Positive Control: MCF7 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated WB HLA-DMA monoclonal antibody (M01), clone 3F12-F11 Western Blot analysis of HLA-DMA expression in U-2 OS on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hela 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using HLA-DMA, antibody at 1:250 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IP, WB HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in mouse kidney. HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in HeLa. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of HLA-DMA expression in transfected 293T cell line by HLA-DMA MaxPab polyclonal antibody.Lane 1: HLA-DMA transfected lysate(28.71 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to HLA-DMA on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 3 ug/ml] HLA-DMA monoclonal antibody (M01), clone 3F12-F11 Western Blot analysis of HLA-DMA expression in U-2 OS . 100 μg Log in to see 9 Days
$430.00
Details

HLA-DMA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Mouse (Murine)


Human ,
,
,
, , , , , , , , , , , , , , , , , , ,

Top referenced anti-Major Histocompatibility Complex, Class II, DM alpha Antibodies

  1. Human Polyclonal HLA-DMA Primary Antibody for WB - ABIN611597 : Nagamine, Kudoh, Kawasaki, Minoshima, Asakawa, Ito, Shimizu: Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 references for ABIN611597

More Antibodies against Major Histocompatibility Complex, Class II, DM alpha Interaction Partners

Human Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) interaction partners

  1. DMA*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans

  2. HLA DMA and DMB show no association with rheumatoid arthritis in US Caucasians.

  3. The results suggest that HLA-DMA*0104 may represent a novel allele of susceptibility to systemic lupus erythematosus.

  4. HLA-DMA may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.

  5. The absence of HLA-DR/DM interactions at the limiting membrane prevents local loading of MHC class II molecules in phagosomes

  6. glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta (show GPHb5 Antibodies), while DMbeta (show GPHb5 Antibodies) forms disulfide-linked homodimers without DMalpha

Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) Antigen Profile

Protein Summary

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Gene names and symbols associated with HLA-DMA

  • RT1 class II, locus DMa (RT1-DMa) antibody
  • SLA-DM alpha chain (SLA-DMA) antibody
  • major histocompatibility complex, class II, DM alpha (HLA-DMA) antibody
  • histocompatibility 2, class II, locus DMa (H2-DMa) antibody
  • D6S222E antibody
  • DMA antibody
  • H-2Ma antibody
  • H2-Ma antibody
  • HLA-DMA antibody
  • HLADM antibody
  • RING6 antibody
  • RT1.DMa antibody
  • RT1.Ma antibody

Protein level used designations for HLA-DMA

RT1 class II, DM alpha , MHC class II-like alpha chain , major histocompatibility complex, class II, DM alpha , H2-M alpha , class II histocompatibility antigen, M alpha chain , histocompatibility 2, class II, locus Ma , HLA class II histocompatibility antigen, DM alpha chain , MHC class II antigen DMA , really interesting new gene 6 protein

GENE ID SPECIES
294274 Rattus norvegicus
445528 Sus scrofa
481732 Canis lupus familiaris
14998 Mus musculus
3108 Homo sapiens
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